Cytochrome P450 Homepage

This is a list of all known cytochrome P450 accession numbers from PIR 44 (4/12/95)

SwissProt 31 (3/20/95) and GenBank 89 (6/9/95).

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of the 477 sequences in the alignment, how many families, subfamilies, how many

plant familes, mammalian families etc.

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The distribution of P450s in each family between major biological classes (mammals,

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A European P450 WWW Server

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Kirill Degtiarenko has also set up a cytochrome P450 WWW server in Trieste, Italy.

This server has features not included here, such as hyperlinks to the database

entries for Genbank and SwissProt accession numbers. He has some bibliographic

information that is different from the file maintained here. Some additional types of

sequences are also included, such as NADPH cytochrome P450 reductases and

The larger files of the alignments, the bibliography and the accession number table

will be posted on Kirill Degtiarenko's server to help those having difficulty in down-

loading these files from the UK and Europe. I can see from the usage log that many

of you have not been able to get these larger files intact.

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A Protein Family Classification Server

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MIPS (Martinsreid Institute for Protein Sequences) has a server that has sorted families

and superfamilies of proteins. These families are listed with their member's PIR

accession numbers, and alignments made by pileup can be obtained for the families.

The superfamily number for P450s is 0027.0 and this can be connected directly by

The accession number table in my server has all the PIR accession numbers in the

MIPS server, but they are hyperlinked there, so you can get the sequence entry

directly. The URL for the more general section of this server is

http://www.mips.biochem.mpg.de/www/programs/classification.html

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