105  740 intron phase = 00 1 2 ALL INTRON BOUNDARIES ARE MARKED

CYP325H1   ---------- ---------- ---------- --MIVLVFIG VFALVYYVNF

CYP325E1   ---------- ---------- ---------- -----MITLL LLGFGALSLY

CYP325K1   ---------- ---------- ---------- --MLPGLFVL AACLCAVTLS

CYP325D2   ---------- ---------- ---------- ----MFAIVL FLITACVCYY

CYP325C2   ---------- ---------- ---------- --MWWLWLVA LVLAALGLWQ

CYP325D1   ---------- ---------- ---------- ---MFAIVLF LIAACAFLYY

CYP325C1   ---------- ---------- ---------- --MWWLWLVA LVLAALGLWQ

CYP325C3   ---------- ---------- ---------- --MWWFWLVA LVLAALGLWQ

CYP325A3   ---------- ---------- ---------- -MFFIPALIL LLGLVLYWSK

CYP325A2   ---------- ---------- ---------- -MFFIPALIL LLGLVLYWSK

CYP325J1   ---------- ---------- ---------- -MFHTFVQCA LFCVTVYCCR

CYP325B1   ---------- ---------- ---------- ---MQLFLLT LVVIFGAVLY

CYP325A1   ---------- ---------- ---------- -MFFIPALIL LLGLVLYWSK

CYP325G1   ---------- ---------- --------MI DASVVFVLSI AISALCWTAW

CYP325F1   ---------- ---------- --------MT VQLVLVYVVL SLALAILLCL

CYP325F2   ---------- ---------- --------MA LQLVLLYISA ALALATLVCV

CYP4H15    ---------- ---------- ------MFLV LLTTLLGIAV TCMVVTIIRN

CYP4H25    ---------- ---------- ------MFLV LLTTFFGIAI TWLAVTIMRN

CYP4H26    ---------- ---------- -MAVSVLLLF LLATVLLLSA LYIALKVVRN

CYP4H27v1  ---------- ---------- ------MFLV LLSICLGTAF AWMIVTILRN

CYP4H30v2  ---------- ---------- ------MFLV LLAMCLGVVF VWMFFTICRN

CYP4H19    ---------- ---------- ---------- --MLVVVFLV TLLVLAVLRE

CYP4H24    ---------- ---------- ---------- -MSFVLFLLV ILIVYGLAQV

CYP4H14    ---------- ---------- ---------- --MILQALLI AGVVYLLISH

CYP4H16    ---------- ---------- ---------- -MFVLVAVFV VYLSYLLLKY

CYP4H18    ---------- ---------- ---------- -MFWLVTLLA VYVAYLLLKY

CYP4H17    ---------- ---------- ---------- -MMLLVAIVV VYLSYVLFKY

CYP4C26    --------ME NSFASDRIGT VRRGTAALVA VFSPPTLAML LLLALVLVVF

CYP4C37    MAYGDSVLLT SSIGAGSNSW TRQQFIESVP KTSVLLLLSF IFIVCCLAAY

CYP4C25    --------ME SLLGGSLLLS KLS---KVFT LFSPVTLLLL TTVSCAIYVY

CYP4C28    ---------- -----MSSIL WSDLVPNALQ LLSPTAWIVM LTVAASTVIF

CYP4K2     ---------- ---------- ---------- ---MFYWAVV LGVIATLLAA

CYP4AR1    ---------- ---------- ---------- ---MIVYALL IALCVLVLRF

CYP4D15    ---------- ---------- ---------- MWPIIVSGTA LLLSIAIWWT

CYP4D17    ---------- ---------- ---------- MVYSTLAVLL ALGSLAAVYL

CYP4D16    ---------- ---------- ---------- MFVATLTLLA LIASVAFYVY

CYP4D22    ---------- ---------- ---------- -MVVVVQIGL ALLVVILTIN

CYP4AA1    ---------- ---------- MTFFQALEKS SAVELYTYLT LILVCVLLYI

CYP4C35    ---------- ---------- ---------- ---MLLVVLV LLLLTPVLQW

CYP4C36    ---------- ---------- -----MLTGE TVLLVQIALV VIALVPLAKW

CYP4C27    ---------- ---------- -------MSE LSTIFHGVLV FVVFAIYLQW

CYP4G16    ---------- -MSATIAHTD GLNSSANIIS PINMFYFLLT PALLLWFFYW

CYP4G17    ---------- MGIETIPERM AMDETVPGSW VLSVTVATVL LLVAGTLFHL

CYP4J9     ---------- ---------- ---------- MDILTVVLLL VAFLLILYEL

CYP4J5     ---------- --------MA SDWNVVVQSP LVISTLSILL LLLLWFVWDV

CYP4J10    ---------- ---------- --------ML LAVLVCVLGS CIAILLVRDY

CYP304B1   ---------- ---------- ---------- MLATTTLLLW GVAISLLLYA

CYP304C1   ---------- ---------- ---------- ---MMELMLL VALVVLIVSC

CYP307A1  MAYTGLILAVL TIILSVVCYF KILYEWHRKV RIQTVRPSRL QKLATAATTL

CYP307B1   ---------- ----MLLPEL KQKVILRSEV LQALRQLIAS VGVTFGTHED

CYP306A1   ---------- ---------- ---------- -------MIM LMCLVILLLF

CYP15B1    ---------- ---------- ---------- ------MWNG ALIVIVLLSL

CYP305A4   ---------- ---------- ---------- -----MITLT LAALALILLV

CYP305A2   ---------- ---------- ---------- ------MFAI LLGLTVALLC

CYP305A3v1 ---------- ---------- ---------- -----MITLT LAALALILLV

CYP303A1   ---------- ---------- ---------- -------MWY FVALCVVLLL

CYP301A1   ---------- ---------- -------MVE ALNVGTDGAQ TTASSSSSAR

CYP49A1    ---------- ---------- --------MV GQRIANSLLK RSAFSSALNA

CYP12F4    ---------- -------MLK LTTANSLRFR PFGGAVRWRS ATAQPAADTS

CYP12F3    ---------- ---MLMRRCW LMKPIGCTRS GRWRNVQAQA QRNTATAEHV

CYP12F2    ---------- ----MNVLKS PLWQHWLRSS VLPYGTTSNR LLSAQAAVEH

CYP12F1    ---------- -------MAW RTLMQRSRGS TERLCAKRYV NTVAAATKQY

CYP314A1   ---------- ---------- ---------- ---------- ----------

CYP315A1   ---------- ---------- -------MLQ RLRGTGSRFR CTGGQQQRAG

CYP302A1   ---------- ---------- ---------- --MNLPRQIT KRLRGFSSVA

CYP6AK1    ---------- ---------- ---------- MSLEVVDLLY TVALLLLLYL

CYP6Z4     ---------- ---------- ---------- ----MFVYTL ALFAVVLYLA

CYP6Z3     ---------- ---------- ---------- ----MFVYTL ALVATVIFLV

CYP6Z2     ---------- ---------- ---------- ----MFVYTL ALVAAVIFLV

CYP6Z1     ---------- ---------- ---------- ----MILYTI GLIVTFVFLA

CYP6AF1    ---------- ---------- ---------- MALPIALYLC VSVVCLLVLW

CYP6AF2    ---------- ---------- ---------- MALPIALYLC VSVVCLLVLW

CYP6AH1    ---------- ---------- ---------- MLEFYVAVIV LAVCLYFKWS

CYP6AJ1    ---------- --------MF VSSLLLGGLF YHHPLVAVPL IALVALFYWL

CYP6AG2    ---------- ---------- ---------- -MLLILFGTV VAFVALVYIF

CYP6AG1    ---------- ---------- ---------- --MFVTVTLL VTAITFVYVY

CYP6S2     ---------- ---------- ---------- -MLIVAVFVA FFGIFWIYFH

CYP6S1     ---------- ---------- ---------- -MFVQFLLVV SLGWLWIYLH

CYP6R1     ---------- ---------- --------ML IVAWLLSAVL SLCFVLCVIH

CYP6N2     ---------- ---------- ---------- ----MLLYLL LLAVTAAIWY

CYP6Y2     ---------- ---------- -----MELVV TSVISLGVLL ATLCLCVYLL

CYP6Y1     ---------- ---------- ---------- -MFLQLVGVV LAIVLSCLAW

CYP6M1     ---------- ---------- --------MW FPTIEVLVAL LALLGGAVYF

CYP6N1v2   ---------- ---------- ---------- ----MWIHLL VITLLVAVYW

CYP6M2     ---------- ---------- ---------M FSLLDFTFLV AALAAGLYYY

CYP6M3     ---------- ---------- ---------- MEPLDILISV VMLCLAVYFL

CYP6M4     ---------- ---------- ---------- MEFYDVAVTV GMLCIIIYLL

CYP6AA1    ---------- ---------- ---------M GYVSVVLFLV VPALTLLYLY

CYP6AA2    ---------- ---------- ---------- --MTVWLLLV VVVATLLYYY

CYP6P3     ---------- ---------- ---------M ELINAVLAAF IFAVSIVYLF

CYP6P5     ---------- ---------- ---------M EPVTIVLTAF IFVVSIVYLF

CYP6P4     ---------- ---------- ---------M DLLSYVLTAF VFVVSIAYLY

CYP6P1     ---------- ---------- ---------M SLLGVLLLGV VLLLSLAYLF

CYP6P2     ---------- ---------- ---------M ELLTLTLSLL VALATGLYLF

CYP6AD1    ---------- ---------- -------MVA FTWVLVLCTI VLTGVAVRMF

CYP9J3     ---------- ---------- ---------M EISVVTLALL VGLCVAVYRY

CYP9J4     ---------- ---------- ---------- ------MAAI ATILALLYYY

CYP9L3     ---------- ---------- ---------- -MYLVYVGGI VSLLMVLYAY

CYP9L2     ---------- ---------- ---------M EIHLVYVIGI VSLLVALYVY

CYP9L1     ---------- ---------- ---------M EINLMYVIGI VSVLVALYVY

CYP9J5     ---------- ---------- ---------M EISLMVLVPL VAILGFIYHY

CYP9K1     ---------- ---------- ---MLGTLAS LLFSLEGVLL VALLALLYYY

CYP9M1     ---------- ---------- ---------- ---MFLLWAL PLALYLLYRW

CYP9M2     ---------- ---------- ---------- ---MFLLWAL PLALYLFYRW

CYP329A1   ---------- ---------- ------MNQE DLYWFTFILV TLLGFFTYKL

 

CYP325H1   RRTR------ -KRLYELAER IPGPF-DYPL IGSMLLTIGK SPL-------

CYP325E1   LYCK------ -IKFKFAEKI PCVEP-LHPI FGNGLEFAQK NSY-------

CYP325K1   WYWK------ -QRLRWADDI PRARP-THRW LGNVGDFLGK SPG-------

CYP325D2   YTCV------ -VRARFAQDV PCAQP-CYPL IENGLSFLEK SPV-------

CYP325C2   WWIV------ -QRHRFASHL PVMQP-YYPI IGNAQLFIGK SGV-------

CYP325D1   YTCV------ -VRARYAQDV PCAQP-CYPL IGNGLSFLEK SPV-------

CYP325C1   WWIV------ -QRHRFASHL PVMQP-YYPI IGNAQLFIGK SGV-------

CYP325C3   VWIV------ -QRHRFASHL PVVQP-YYPI IGNAQLFIGK SGV-------

CYP325A3   LSRK------ -TSAQLFGKD IPGPR-SYPL IGSAHLFLGS DE--------

CYP325A2   LSRK------ -TSAQLFGKD IPGPR-SYPL IGSAHLFLGS DE--------

CYP325J1   WWQM------ -RERWKLLSR LPGPR-CFPL IGAMYVIPGR DTS-------

CYP325B1   RKHQ------ -KMFKFAEKI EMLHS-YVPV FGHSLLLLGK LPE-------

CYP325A1   LSRK------ -TSAQLFAKD IPGPR-SYPL IGSAHLFLGS DE--------

CYP325G1   RLHK------ -WKHYKLSAD LPGPR-DFPL IGSAHLFFGK NTG-------

CYP325F1   RWKR------ -RKLYAAAAT MDGPP-CVPF LGHAYLLFGK QTG-------

CYP325F2   RWKR------ -RKLYAAAAT MDGPP-CLPL LGHVYLIFGK RCG-------

CYP4H15_   RATV------ -AKLKKQLHN FTVIP-AIPV LGSAYLFKDP TPE-------

CYP4H25_50 RATV------ -SKLKKQLPH FTVIP-AIPV LGSAYHFKDP TPE-------

CYP4H26_   RNRA------ -VALLKQLPN FRALP-SVPL LGSAHLFLDT TPD-------

CYP4H27v1  RVAV------ -LMLQKRLPN FKVVP-AIPV FGSTYHFKDL SAE-------

CYP4H30v2  RATV------ -LMLQKRLPN FKVIP-AIPV FGSMYHFKDP SAE-------

CYP4H19_   YRDR------ -KRLQHIASH FQGPK-PHWL LGYLPLFPVN DIP-------

CYP4H24_50 YRKR------ -RRLHRIAAH FDGAK-PHWL LGNVMEYPAN DIP-------

CYP4H14    LIER------ -KKLQKINKH FPGPK-PLPV VGNLLQFAWL DIP-------

CYP4H16    HQKR------ -QERLKLLRY FPGPQ-PEYI LGCSYLFYNK SIT-------

CYP4H18    HQQR------ -QKLLAIRAK FGGPE-SSYF LGTFYLFKDK SIP-------

CYP4H17    HQKR------ -QQLLEIAKY FKGPR-ADYF LGCFYLFRNK SVA-------

CYP4C26_   KARR------ -AKMVKLIDQ IPGPV-CMPL VGNGLQINVG CKD-------

CYP4C37    LERY------ -RRLVRHINC IPGPA-TLPI IGNALLINA- DRE-------

CYP4C25_   NRRR------ -AHIVRHIDK IPGPA-GLPI LGNTLHINV- DHD-------

CYP4C28    YRQR------ -AEVAKHINR IPGPP-ALPL LGNSLQWLVD RD--------

CYP4K2     LDWK------ -YKSY---EH LPGPR-RWPF IGNVVSFLGA GPV-------

CYP4AR1    VAFR------ -YKVYRTVGH LPGPP-VNFL LGNTLELVRY DTQ-------

CYP4D15    VANF------ -GSALRYAGK LGGPV-AYPL VGNGFLFINK TPA-------

CYP4D17_   YRRF------ -GEMLKHTGK LGGPP-AYPI LGNGLMFLNK SPA-------

CYP4D16_   VERF------ -SKILKHSGK LGGPR-AYPL IGNGLLFAGK TPA-------

CYP4D22    YLLV------ -RQNIKYGRH IPGPV-PLPI VGCFYLYINL KPE-------

CYP4AA1    FSDY------ -LKICALAFR LPGPK-SYPI IGNCLDIARK D---------

CYP4C35    LIRR------ -VQMSQIYDK IPGPK-AYPF VGTLYLLFGK KSH-------

CYP4C36    IKKR------ -LNLHDVINK IPGPK-AYPI IGTMYTFVGK KSE-------

CYP4C27    LMKR------ -WQLSQIFEK IPGPK-AYPI IGTMYSFIGK QRH-------

CYP4G16_   RLSR------ -RHMLELAER IPGPK-GLPL IGNALDLVGS SH--------

CYP4G17_   WMQT------ -RRYVQLGNL IPGPV-AYPL IGNANMLLGK THN-------

CYP4J9     RVQL------ -STHYRAGKR FPGPR-ALPL LGNAHNLLFN DQR-------

CYP4J5     FDKR------ -GPTYTALRQ FAGPP-VWPL IGTMYHTRRL DAA-------

CYP4J10    RSKQ------ -TDGYRAALR YPGGT-IVPV FGSLFELLFK NPV-------

CYP304B1   LVRP------ -LTARPGKNF PPGPPGRFPF LGDYGLLLLI N---------

CYP304C1   AIRY------ -ALHRPSERF PPGPP-RLPL LGSYPFLLAL N---------

CYP307A1   PQQS------ -TTELMTFPQ APGPV-PWPI LGSLAFLGQ- YD--------

CYP307B1   EPVG------ -AASHALEKP APGPK-NYPI IGALKELNG- YE--------

CYP306A1   CCIF------ -ITLLSRHKK PPGPY-GFPF IGCLTLIDP- ----------

CYP15B1    LYCC------ -WDARKPKRF PPGPY-WLPF IGSGLVMLKL VRSL------

CYP305A4   AFLV------ -KELWRPANY PPGPR-WLPI VGNTPLIRKM ASQH------

CYP305A2   AYLI------ -NEFRRPANY PPGPP-WLPI VGNTPYIRKL ARQY------

CYP305A3v1 AFLV------ -KELWRPANY PPGPR-WLPI VGNTPLIRKM ASQH------

CYP303A1   LWLH------ -LDNLKPLNF PPGPK-WYPI VGSALSIMNA RNKT------

CYP301A1   NTIR------ -LEDARPYSE VPGPK-PLPI LGNTWRVFPI IGQY------

CYP49A1    VNEQ------ -FSHARPYSD VPGPK-GLPM IGNSWRFAPI IGQY------

CYP12F4    VDPE------ -WENALPFEK IPAPS----L LGFLKEFGPF -GKY------

CYP12F3    IDPE------ -WASAKPYKS IPGPT----L WQLFRGFSKG -GCY------

CYP12F2    VDPE------ -WSTAKPYES IPTPS----F MEMTRMFGNK -GRY------

CYP12F1    IDPE------ -WSNAKPYKA IPSPK----L LAFAKEFKEG -GRY------

CYP314A1   ---------- -----RSIWD IPGPR-RLPL IGTKWRYFFG -RHR------

CYP315A1_  VAGD------ -SRGAKPFAE MPGPR-RIPL LGMLNDVMQL -GKP------

CYP302A1   NKPS------ -KRTVKSFDE IPGPR-GPLG LGNLYQYIPG IGRY------

CYP6AK1    GWRK------ -QTYWTRAGV PY-IP-EIPI IGNFATIFLQ RHS-------

CYP6Z3     LRYV------ -YSYWARQGF PH-LR-PEIP YGNLRALAEK RE--------

CYP6Z4     LRYI------ -YSHWERHEL PH-LK-PEIP YGNIRTVAEK KE--------

CYP6Z2     LRYI------ -YSHWERHGL PH-LK-PEIP YGNIRTVAEK KE--------

CYP6Z1     LKYV------ -YSYWDRQGL PN-LR-PEIP YGNLRILAQK KE--------

CYP6AF1    IRRR------ -RNYWSTRNV PT-IP-GHFL LGNFEGLRR- -Q--------

CYP6AF2    IRRQ------ -RNYWSTRNV PT-IP-GHFL LGNFEGLRR- -Q--------

CYP6AH1    CSY------- ---WTRQGGV AG-PK-PLPI FGNLFEQLTG QK--------

CYP6AJ1    VKHN------ -YKFWEIDGV PY-PK-PSLL TGNLGPSLAL KK--------

CYP6AG2    LTWE------ -FGFWEKYGV KG-PK-PKIL LGNIPYLLTK KR--------

CYP6AG1    LAWY------ -SNYWTKRGV PG-PA-PRLL FGNFPSFILR NR--------

CYP6S2     FRQR------ -YLFWLNRDV PY-LE-PTFP FGNMIDIFNP NI--------

CYP6S1     FKQR------ -YRFWAERQV PF-LE-PSFP AGNVPDTLKP TI--------

CYP6R1     IRKK------ -YSFWSERGV PF-VP-ARFP LGNIQ----- ----------

CYP6N2     VRRK------ -YTFWADRGV PY-VK-PRFP FGNIQGIGR- RM--------

CYP6Y2     VVRK------ -YSFWRSYHV PY-VE-PELP YGNFKEMGK- SI--------

CYP6Y1     IHRR------ -YHFWKDRSV AY-IK-PRFP FGNFATLGK- VE--------

CYP6M1     IVRK------ -QSYWKERGV PH-PK-PTFF FGSFKDAGT- KI--------

CYP6N1v2   VRQR------ -FAYWEKRGV PY-VP-PTFP QGNLAGVGK- KR--------

CYP6M2     LDRK------ -RSYWQDRGV PG-PK-GELL FGNFGSIGT- KE--------

CYP6M3     LDRR------ -FQYWTDRGV PQ-SK-PELV FGNVREVSR- TI--------

CYP6M4     LVRQ------ -FRYWTERNV PQ-LN-PHLL FGDVRDVNK- TH--------

CYP6AA1    LKQH------ -YRHWANRNL PQ-LE-ASFP LGNMKGVGS- EI--------

CYP6AA2    VWRR------ -YRYWRDRGI AE-LD-PSFP LGDMKGVGT- TR--------

CYP6P3     IRNK------ -HNYWKDNGF PYAPN-PHFL FGHAKGQAQ- TR--------

CYP6P5     VRSK------ -HRFWKDQGV PHAPK-PHLF YGHVKGQSR- TR--------

CYP6P4_    LRSR------ -HNYWRDRCF PYTRQ-KPHL LYGHMEQFQ- SK--------

CYP6P1_    LRSK------ -HNYWRSRGF PCKPS-PSLL YGQMQGNGT- TR--------

CYP6P2_    VRNR------ -YNYWSNRQF PTLPN-QKLL FGHVKGVNT- ER--------

CYP6AD1    LRRR------ -QTFWQRHGI PAARH-PHPL YGNVGGLVT- KH--------

CYP9J3     VTKN------ -YFYFADKPI PF-MK-PSFP FGNAGPILMK KV--------

CYP9J4     VRNR------ -YRYFLDKPY PH-LK-PTFL LGSSAPMMLR RR--------

CYP9L3     LTYN------ -NDFFKKYPI PC-LP-VEPL FGSCRRLMLK QI--------

CYP9L2     LTRN------ -NNFFKSFPI PC-ME-VEPL FGSHRKLLLK QI--------

CYP9L1     LTHN------ -NDFFKKYPI PC-LP-VEPL FGSSRQFLLK KI--------

CYP9J5     ITKG------ -NKYFHDKPI PS-LA-AEPL FGSTRRLMMK QT--------

CYP9K1_    VVVRS----- -TRFFADRGV PY-LP-PVPL LGNGADFITR KR--------

CYP9M1     SIAT------ -YDYFEKRNI PY-VK-PVPF FGQVWSFFTQ EK--------

CYP9M2     SIAT------ -YDYFEKRNI PY-VK-PVPF FGQVLSFFTQ GR--------

CYP329A1   LTRH------ -RSYFRLLRV PF-ER-PHFL YGNLDDVLSG KL--------

 

CYP325H1   ----ELV--- THLMELMHHL P--SPMRAWL GPFLLVVVDR -PEMVQDVLS

CYP325E1   ----EIF--- KSLTRAYKDN K--RIFKLCF GPIPVICPTH -PDLIQKIMT

CYP325K1   ----EVF--- LVLDRHFRQH D--RLFTLRF GSQLAIGLTH -PELVQKVLT

CYP325D2   ----KLF--- QNVVQPFNQF D--RWFKVWL GPQLMLCTSH -PVLAESVLS

CYP325C2   ----DLF--- NQLLQPFRQY D--GWFKIWL GPKLVLATSH -PDIMNAVLS

CYP325D1   ----KLF--- QNVVQPFNQF N--RWFKVWL GPQLMLCTSH -PVLAESVLS

CYP325C1   ----DLF--- NQLLQPFRQY D--GWFKAWL GPKLVLATSH -PDIMNAVLS

CYP325C3   ----DLF--- NQILQQFRQY D--GWFKAWL GPKLVLATSH -PDIMNAVLS

CYP325A3   ----RTF--- SVINELFRKY G--SFFKLSL GPKTFLCLSD -PDLIQQALT

CYP325A2   ----RTF--- SVINELFRKY G--SFFKLSL GPKTFLCLSD -PYLIQQALT

CYP325J1   ----RYL--- ETIIGLTGAY G--SPYCIWL G-SVPVVIVS -SADHATILT

CYP325B1   ----KVF--- QIFKSAYLQH D--RLFQLRL GLMLFVCSSH -PDIMHAVLD

CYP325A1   ----RTF--- SVINELFRKY G--SFFKLSL GPKTFLCLSD -PDLIQQALT

CYP325G1   ----EQF--- RCILDITKAH R--SPCRVWL GPKLFVFIDN -ADDLQTVLN

CYP325F1   ----EHII-- EVFDKYAPRY N--SPIGIWM GPKLIVAIKD NPEYFQKVMN

CYP325F2   ----EDIL-- QVLDRYAPRY K--SPIGIWM GPQLIVGIKD NPDYFQTVMN

CYP4H15_   ----GIF--- QTFTGFHRQF G--RNLITQS LFNFPSMQVC DPKVIEQIM-

CYP4H25_50 ----GIF--- NTFTGFHKQY G--RNLIAQG LFNVPSMQIT DPKVIEQIM-

CYP4H26_   ----GTL--- RTIVDCHQRY G--RNLLLQE LGNEFKLLTC DPRVIEQVL-

CYP4H27v1  ----GLF--- TTFIGLHKLY G--KTLITQS LFNLPSLHVS DAKVIGQIM-

CYP4H30v2  ----GIF--- NTFCDFDTQY G--KTLITQS LFNFPSIHVC DAKVIGQIM-

CYP4H19_   ----GIF--- ETMVKLHDRY G--QDLFNWG LLNDHMVVVT SAANVEKVV-

CYP4H24_50 ----GIF--- ETMVALHKRH G--KDLFNWG LLNDHMITVS SAANVEKVV-

CYP4H14    ----GVF--- EKVVELHQTH G--QDYMMWS LFNWTILMMT SRKNVEKVL-

CYP4H16    ----EIF--- DTIVDSHAQY G--KDICLIG AFNMLELEIA SAQNIEKVL-

CYP4H18    ----DIF--- DLVVGLHKRY G--QDVAIIG AFNDLVLDLS SSKNVEKIL-

CYP4H17    ----EIF--- DLLNDMHRKY G--HDVTMIG AFNDLVLDIS STQNVEKVL-

CYP4C26_   ----ELFDRI IASRKMFGRR Q--GISRVWN G-PIPYVLIS KAAAVEPILS

CYP4C37    ----ELFNRI IASRKLYGRR Q--GITRIWN G-MTPYVLIS QAQAVEKILS

CYP4C25_   ----EIFNRI IAIRKLYGRI Q--GFSRAWN G-PLPYVMIS KASAVERILG

CYP4C28    ----EMFSTI NGARLLYGRR Q--GFNRVWA G-LKPYILIS KATAAERILS

CYP4K2     ----EIF--- DQLIAFASTY G--KVYKLDF F-YDYTIIYS SPEAAEAILT

CYP4AR1    ----VFF--- EKLFEYFQRY G--MIVRLDM I-NKVWIIFS SPHDIEQIIS

CYP4D15    ----EFL--- QLLGRLIAQY G--KCLRVWL G-TQLIVLIT DPKDIEILLS

CYP4D17_   ----DFL--- RIIGELLQRY G--DCFRVWL G-TQLVIVMG DPKDIEVLLS

CYP4D16_   ----EFL--- QTVGRLIQQY G--KCFRIWL G-TQMLIVIT EPKDVEAILS

CYP4D22    ----DII--- DFVSDLRKRY G--NLFRVWI G-NRLALFCT NVKYNETVLS

CYP4AA1    ----LIT--- REMAQAYKNY G--PLARVWI F-VFPMFVVF DPNDLKMILS

CYP4C35    ----EIF--- TLIDQRTRQY D--GIHRIWV G-MTPEVRLS RAEYVEQIIG

CYP4C36    ----EIF--- YIIDKRTRDY P--EIHRIWN G-FVPEVRIN KAEYVEKLLS

CYP4C27    ----EIF--- YLLDERTRRY P--EIHRVWT G-LTPEVRIS KPEYVEQVIG

CYP4G16_   ----SVF--- RTIIEKGKEY N--EVIKIWI G-PKLIVFLV DPRDIELLLS

CYP4G17_   ----QIM--- EKAMELSYIY G--TVARGWL G-YHLVVFLT EPADVEIILN

CYP4J9     ----RTF--- QLPRGWAATY G--DTYRILV R-GILNLNAF QAKDVEPLLS

CYP4J5     ----KAF--- DAFRRWTSQY G--GSYKLWL NRYLFILNIT RCTEAEPFLS

CYP4J10    ----QTF--- AYARANATRY G--ASYRQWI D-GSVILNVT RVQEAEKILS

CYP304B1   --YRHLHKAA LVLGDYYRTK -----ILGIS LRDYPSIVVN DLTVAKEVLN

CYP304C1   --YHHLHRAA ARLSQLYRSK -----LVGLY LGPLPAVLVN DHETVRQVLQ

CYP307A1   -------VPF EGFTALAKKY G---DLYSIT LGSTRCLVVN NLDLIREVLN

CYP307B1   -------VPY QAFSDMGQRY G---PVTALR LGSVNAVVVN GFESIKEVLI

CYP306A1   ------LKPY ETFSRLARQY G---TTYGLW MGQVYTVVLT DPTLIRTILS

CYP15B1    ------HYFH LMWSKLCHQY G---PIVGVR FGQDRIIVVS GREAIRAMYA

CYP305A4   --GGLLANVF DKLSESYQSS -----VIGLK LGRERVVVGL GYAEMKDILC

CYP305A2   ---GGQHKVF ELLGKTYRSD -----VIGLK LGREYVVVAL NYPAVNEVHR

CYP305A3v1 --GGLLANVF DKLSESYQSS -----VIGLK LGRERVVVGL GYAEVKDILC

CYP303A1   ---GMLCKAV EHIAQDYPDH R---GVIGFK IGKDKAVMAI NAESLKEMMN

CYP301A1   ----KISDVA MISFLLHRDY GRIVRLGGLI GRPDLLFVYD CDEIEKVYRN

CYP49A1    ----KIEDLD KVMQDLHRQY GRIAKVNGLI GHPDLLFVFD ADLIRDTFKR

CYP12F4    ----KDGNLY DINKRLRELY GPILRMNGSF GREDLVMTFV PEDFEKVLRS

CYP12F3    ----DGLNLI ELHIRLRQEY GDIYRIPAAM GRADVVMSFA PEDFEKVFRT

CYP12F2    ----ANLDLV ELHSRMWEDY GDIIRFKGMF GRRDIIMTYS PPDIEKVFRN

CYP12F1    ----YELTGA DLFAQWREDY GDLIRIKGIF GRPDIVVTFQ PEDFAKVFRT

CYP314A1   -----YAKVH ETFMEMHRRY GPIMLDVDTV ---PIVNLFD RADMEKVLRY

CYP315A1_  ------AELH LRISKYHEQY G--DLVRLQI GTQNAVFVRD PSLMRKTFQL

CYP302A1   ----SFDELH RSGEDKYRQY G--SIVRETM VPGQDIVWLY DPDDVATVLD

CYP6AK1    -----SFEYI EHIYHHARTR T--SDFFGVN IFTRPALVLR SPELIKRLTC

CYP6Z3     ----SFGVAV NELYTRSTER ----LLGVYL FFR-PAILVR DAHLAKRILV

CYP6Z4     ----SFGIAI NNLYHKSSDR ----LLGIYL FFR-PAILIR DPHLAKRIMV

CYP6Z2     ----SFGTAI NNLYHKSSDR ----LLGIYL FFR-PAILIR DPHLAKRIMV

CYP6Z1     ----SFNVAI NDLYDRSSER ----LVGVYL FFR-PAILVR DAHLAKRIMV

CYP6AF1    ----SVADVS NELYRQVDRR ---ERFCGLS IMLQPTLMIT DLDLIKSVLI

CYP6AF2    ----SVADVS NELYRQVDRR ---ERFCGLS IMLQPTLMIT DLDLIKSVLI

CYP6AH1    ----HFGEIF EEMYRAFPQA S---WIGYYK ISNQPGIVVR DLELVKEVLT

CYP6AJ1    ----HISELA SDWYNAYPDK P---FVGYFK IFT-PAIMVK DPVLVKNILS

CYP6AG2    ----HTVYNY DQLYNDFKNE P---AVGFFS IRS-PQLMVR DPELIKEVLS

CYP6AG1    ----PFVDDF QDIYDKYRSK G--NVIGVFN GRQ-PAVLVM KPELIKDVLI

CYP6S2     ----HFAHLI QKLYRQLKDR G---DYVGLF FFRDPVLLVL SPEFARTVMV

CYP6S1     ----HFAYII EKLYKRLKSK G---DYVGIY FFRDPVLLVL SPEFARTVLV

CYP6R1     ----HASHLM LDLYRALKGK ---HPFGGIF QFTEPVAMIT DPEMIRNVLV

CYP6N2     ----HSSQLM TKFYNEMKTS G--RPFGGIY FFTNPVALAL ELDFVKNVLV

CYP6Y2     ----HPAHLS QRFYEQYKAV PGSPGFVGLY IFLNPVLLVT DLKLAKRILI

CYP6Y1     ----HIAPIT QRHYDHFKRQ --NVPYGGVF MLTSPLLYIF DTKLIKQLLV

CYP6M1     ----HFTEEV ERHYAIYKGK ---HPFIGVY MLTTPVVLPL DLELIKAIFV

CYP6N1v2   ----HMSEIL QSCYKQLKSS G--RPYGGIH FFINPVALLI DPDLIKTVLV

CYP6M2     ----HITVPF KRIYDDNKGK ---HPFAGMY QFVKPVALIT DLELLKCVFV

CYP6M3     ----HLADKF REIYNELKGK ---HPLVGVY LFFKPVALIT DLELLKCVFV

CYP6M4     ----HIGEKF RQLYNELKGK ---HPFGGIY MFTKPVALVT DLELVKNVFV

CYP6AA1    ----HFNDVL NEAYAKGKAQ S--APLVGLY FMLKPILIVT ELDMVKRILV

CYP6AA2    ----GFNDML DEAYGRVRGK S--AAVG-VY FLISPILIVA DLDLAKQILV

CYP6P3     ----HGADIH QELYRYFKQR G--ERYGGIS QFIVPSVLVI DPELAKTILV

CYP6P5     ----HGADIN QELYRYFKQR G--VPYGGIS LFIMPSLIVV DPELVKTILV

CYP6P4_    ----HASYIN EELYWEFKNR G--EPIGGMS MFFLPGLIVA DPELVKSILV

CYP6P1_    ----HAAYVT QEIYRYAQDR G--ERYMGYS FFFMPIVMVC DIELVKTVLV

CYP6P2_    ----HASYIS SEIYREFKKR G--DAFGGFN MFVIPAVMAI DPEFIKTILV

CYP6AD1    ----HTATVL QRLYREFRER K--LPAGGFN LYFSPVLLVV DRQLIERVLV

CYP9J3     ----TLFEHF KNLYDAFPNA R---IHGTFN MRQ-PVYIVR DPELVKQITV

CYP9J4     ----NMIQHI EALYYSHPDA K---VIGAYD LLT-PNVLLR DPDCVKQIGV

CYP9L3     ----SFNDFV RSNYDRFQGA K---IFGMFE VLT-PMFVIR DPELIKQITV

CYP9L2     ----SLHDFV RSCYERFPNA K---IFGLFE MIT-PMFVVR DPELIKQITV

CYP9L1     ----SFSEFV RSNYERFPNA K---MYGMFE MFT-PMFVIR DPELIKQITV

CYP9J5     ----SFHDFV ISIYNKYPLV K---VFGMID TML-PMFVVR DPELLKRIAV

CYP9K1_    ----LLTDVL SDMYHRFASH R---FFGYFD FLS-PIYVVR DLELVKQICI

CYP9M1     ----HAVDVA SEGYHMFPNT R---ISGVFT LRT-PAYLVH DPALFKEMAI

CYP9M2     ----HAVDVA SEGYHMFRNT R---ISGVFT LRT-PAYLVH DPTLYKQMAT

CYP329A1   ----TTMEKL EQFYRKFSNH G---LFGFFN YMT-PALYVR DPALIRQLLQ

 

CYP325H1   SPDCVQKPFM YDFFRLSKG- ---------- LFG-APADQW KRHRK----L

CYP325E1   EQASMDKPFV YDFMRVDHG- ---------- LLT-AQYDEW RVHRK----A

CYP325K1   HPDCQAKPDL YKVVRLPNG- ---------- LLA-AKYDVW KVHRK----T

CYP325D2   HPKCLDKPFF YSFVQLE*G- -----------ILT-RKYQNW KRYRK----V

CYP325C2   HPDCLEKPFF YDFVKLEHG- ---------- IFA-GHYHPW KTQRK----A

CYP325D1   HPKCLDKPFF YSFVQLEQG- ---------- ILT-RKYQNW KRYRK----V

CYP325C1   HPDCLEKPFF YDFVKLEHG- ---------- IFA-GHYHPW KTQRK----A

CYP325C3   HPDCLKKPFF YDFVKLEHA- ---------- IFA-GHYHLW KTQRK----A

CYP325A3   SSACQDKAFF YRFMELDYG- ---------- LIS-SRYTDW KLYRK----S

CYP325A2   SSACQDKAFF YRFMELDYG- ---------- LVS-SRYTDW KLYRK----S

CYP325J1   SPATVEKASF YRFT-PLQG- ---------- IFS-LPADKW RAHRK----L

CYP325B1   NPKSMNKPML YDFFKLDQG- ---------- LFA-TPYGLW KHQRK----T

CYP325A1   SSACQDKAFF YRFLELDYG- ---------- LIS-SRYTDW KLYRK----S

CYP325G1   AGQCLEKADV YRFFQCETG- ---------- LFS-APAPVW KVHRK----H

CYP325F1   SPHLLSKMDQ YNFFRAENG- ---------- LLT-APEHVW KTERK----L

CYP325F2   SPHMLNKMDQ YNFFRIVNG- ---------- LFA-APDHTW KNERK----L

CYP4H15_   QARTIEKTII YDFMVPWLG- --------TG LVV-STGTKW AQRRK----I

CYP4H25_50 QARTIEKTII YDFMIPWLG- --------TG LAI-STGAKW AQRRK----I

CYP4H26_   QAKTIVKSNF YRFLLPWIG- --------LS SVV-VSGHRW HNRRK----V

CYP4H27v1  QARTVEKTIV YDFMTPWLG- --------TG LIV-STGSKW TQHRK----I

CYP4H30v2  QARTIEKTII YDFMTPWLG- --------TG LIV-STGSKW TQRRK----I

CYP4H19_   MAKKTQKSQI YEFIEPWLG- --------QG LLI-SSGEKW FHRRK----I

CYP4H24_50 MAKRTEKSSV YEFIELWLG- --------QG LLI-SKGEKW FHRRK----I

CYP4H14    LAKQTEKALL YQFIEPWLG- --------TG LLI-ASGEKW FQRRK----I

CYP4H16    LAKTTKKSYQ YDFLEPWLG- --------TG LLL-SFGEKW FQRRK----I

CYP4H18    LAKTTKKSFV YDYLEPWLG- --------TG LLI-SFGEKW FQRRK----I

CYP4H17    LAKTTKKSFP YEFLEPWLG- --------TG LLL-SFGEKW FQRRR----I

CYP4C26_   NPKLVEKSND YEYMKAWLG- --------NG LLT-SPGYIW HPRRK----S

CYP4C37    STKNIEKGRD YEFLQPWLG- --------TG LLT-SPASKW QHRRK----I

CYP4C25_   SQKHIEKSHD YEFLKPWLG- --------TG LLT-SAGKKW HPRRK----I

CYP4C28    SSKNIEKGRD YDLLKPWIG- --------TG LLT-SHAAKW HQRRK----M

CYP4K2     SPAFTAKSQD YDKVSEWIG- --------NG LLI-SRDQKW FTHRK----V

CYP4AR1    SNEFNRKSMD YDILQEWLG- --------NG ILL-DYGNTW FSNRR----A

CYP4D15    SPKYIEKSSE YDFVRPWLG- --------EG LLI-SSGRKW QTHRK----I

CYP4D17_   SPKYIDKSTE YDFIRPWLG- --------EG LLT-SRGRKW HTHRK----V

CYP4D16_   SNKYIDKSIE YDFIRPWLG- --------EG LLT-STGRKW HTHRK----V

CYP4D22    SQKLIRKSEL YKFLIPWLG- --------DG LLL-STGQKW FGKRK----I

CYP4AA1    SKKHTNKSMF YKLLHNFLG- --------RG LIT-SSGHKW SSHRK----L

CYP4C35    ASKHTEKATL YRFLGDWLG- --------EG LLT-SKGERW FQHRK----L

CYP4C36    SSRNIEKSMT YKFTRDWLG- --------QG LLT-SKDDRW FQHRR----L

CYP4C27    SSKHIEKATM YRFLHDWLG- --------NG LLT-SKGERW HQHRK----L

CYP4G16_   SHVYIDKSPE YRFFKPWLG- --------NG LLI-STGHKW RQHRK----L

CYP4G17_   SYVHLEKSSE YRFFKPWLG- --------DG LLI-SSGDKW KSHRK----L

CYP4J9     SPKLIEKSMI YSLLHRFLG- --------IG LLN-STGSKW QHRRR----I

CYP4J5     GSRNTEKSLL YRFMYPFIG- --------VG LLN-SAGAKW LQRRR----I

CYP4J10    STQHTRKSIL YRFLHPLMG- --------DG LLC-SKGAKW QQRRR----I

CYP304B1   RK--VFDGRP DLYLARIRD- ----RDYNRR GIFFTDGPSW KEQRW-FILR

CYP304C1   RS--EFDGRP DLFLARLRD- ----ERYARR GIFFTDGDSW REQRK-FFLK

CYP307A1   QNGRYFGGRP DFLRFHKLF- ----GGDRNN SLALCDWSTL QQKRRNLARK

CYP307B1   NKGQHFDSRP NFRRYQLLF- ----SGNKEN SLAFCDWSEV QKARRDMLVP

CYP306A1   KDEATGRAPL FITHGIMGG- ---------H GIICAQGNLW RDQRR-LSID

CYP15B1    KD--QFDGRP DGYFFRMR-- ----SFGQRL GVALTDGSHW EVQRK-FAVR

CYP305A4   NE--AFQGRP DNFFIRLR-- ----TLGTRL GITCTDGSFW NEQRS-FVTR

CYP305A2   ND--VFTGRP DNFFIRLR-- ----TMGTRL GVTCTDGAFW AEHRN-FVTR

CYP305A3v1 NE--AFQGRP DNFFIRLR-- ----TLGTRL GITCTDGSFW NEQRS-FVTR

CYP303A1   NE--DFDGRP TGIFYETR-- ----TWGLRR GVLLTDEQFW QEQRR-FIVR

CYP301A1   EGPTPFRPSM PSLVKYKSEL RKDFFGDLPG VVG-VHGEPW REFRS----R

CYP49A1    EDVLPHRPAM PSLRNYKSKL RKDFFGDNMG LIG-VHGEKW DAFRA----Q

CYP12F4    EGPWPRRTGM DSFVYYRKQH RPEYFKGYGG LLA-EQGEDW HKMRT----I

CYP12F3    EGQYPVRRSF DTMTYYRQQV RPDIFGELGG LVT-SQGESW QKMRR----I

CYP12F2    EGQWPIRRGF DSFTYYRTHV RPDIFSETGG LVT-EHGEKW QKVRT----I

CYP12F1    EGAWPIRRSS ATLSYYREKV RPEVFGELSG LIT-TQGETW QQLRT----I

CYP314A1   PSRYPFRPPT EIVEVYRSS- RPDRFG-VTN LIN-AQGAKW HELRA----K

CYP315A1_  EGAYPRHPLP ESWTYFNKK- ----HDYQRG LFF-MDGKEW LQSRQ---IF

CYP302A1   DRTPGMYPSR RSHTALEKYR KDRPNVYRTA GLLPTNGAEW WKIRS----E

CYP6AK1    TDAQRFINRQ MCTDPFHDAI G------YFN LIM-IREPLW KQLRG----F

CYP6Z3     ADFQHFHDRG VFCDEHRDPM S-------AN LFA-LPGARW KRLRA----K

CYP6Z4     NDFQNFHDRG VYCNEEHDPF S-------AN LFA-LPGQRW KNLRA----K

CYP6Z2     NDFQNFHDRG VYCNEEHDPF S-------AN LFA-LPGQRW KNLRA----K

CYP6Z1     NDFQHFHDRG VYCNEHSDPM S-------AN LFA-LPGQRW KNLRA----K

CYP6AF1    KDFAHFTDHG VYHNERVDVL S-------CH LFC-LEGAKW KSIRS----K

CYP6AF2    KDFAHFTDHG VYHNERVDVL S-------CH LFC-LEGAKW KSIRS----K

CYP6AH1    SSFSSFNQND FIIDEKLDPL V------AFN PFV-QAGERW KERRG----Q

CYP6AJ1    RDFDCFANND FLLDVRQDPL L------SHD PFL-VTGERW KRSRS----L

CYP6AG2    KGFQNFAEND FSDTVDEKSD P----LLARN PFS-LSGERW KTRRA----E

CYP6AG1    KNFKQFQDNE FADSVSKDSD P----IFGRN PFM-LKGEEW KEKRA----E

CYP6S2     KDFNYFVDRG VYSNEEFDPL S-------AN LFF-MEGAKW RKLRS----K

CYP6S1     KDFNYFVDRG VYSNEEVDPL S-------AN LFF-LEGNRW RKLRS----K

CYP6R1     RDFRHFYNRG GYINRQHDPL S-------GH MLN-SGSERW SVLRH----A

CYP6N2     RDFAHFHDRG VYYNEKDDPI S-------GH LFN-IEGTKW TNLRK----K

CYP6Y2     EDFHHFPDRG VYFNEKDDPL S-------AH LFA-IEGQRW KDLRA----K

CYP6Y1     KDFHHFPNRG VYFNERDDPL S-------AH MFA-IEGQKW RTLRA----K

CYP6M1     KDFQYFHDRG TYYNEKHDPL T-------AH LFN-LEGQKW RNLRN----K

CYP6N1v2   KDFPYFHDRN LYHNDRDDPL S-------RH LVA-MEGSKW KNLRA----K

CYP6M2     KDFQYFHDRG TFYNERDDPL S-------AH LFN-LEGQKW RSLRN----K

CYP6M3     KDFQYFHDRG TYYNEKHDPL T-------AH LFN-IEGQKW KNLRN----K

CYP6M4     KDFQYFHDRG TYYDEKHDPL S-------AH LFN-LEGYKW KSLRN----K

CYP6AA1    KDFSSFHDRG LYVNERDDPL S-------GH LFA-LDGERW RYLRN----K

CYP6AA2    KDFHLFHDRG MYVNERDDPL S-------GH LFS-IGGERW RYLRN----K

CYP6P3     KDFNVFHDHG VFTNAKDDPL T-------GH LFA-LEGQPW RLMRQ----K

CYP6P5     KDFNVFHDRG VYSNPRDDPF T-------GN LFG-LEGTPW RLLRQ----K

CYP6P4_    KDFSVFHDRG VFNDAKADPL S-------AH LFA-LEGHEW RVLRQ----K

CYP6P1_    KDFAVFHDRG MYSNPRADPL S-------GN LFA-LEGHEW RALRQ----K

CYP6P2_    KDFHIFHDRG LFSDPEIDPL S-------GT LFA-LQGKAW KILRQ----K

CYP6AD1    NDFAQFQNRG LYASATVNPL S------SET LFS-VAGERW HRMRQ----Q

CYP9J3     KDFDYFVDHM TTGMEQTEDN NSNHLLLGNS LVS-LRGQKW RDMRA----T

CYP9J4     KDFDYFTDHT PFLPNESDIG -QSDNMFLNS LFM-LRGQKW RDMRA----T

CYP9L3     KDFDHFINHR PLIKADSSMP -NSSVMFTKV LFN-LNDQRW RNVRT----T

CYP9L2     KDFDHFVNHR AILPGDGSSS RNSSIMFTKV LFN-LNGQRW RNVRN----T

CYP9L1     KDFDHFINHR PLMKADNSSN --STAMFSKI LFN-LTGQRW RNVRT----T

CYP9J5     KDFEYFMNHR PVFGNNDDPH --NEALFGKT LIA-ITDQKW RDMRA----T

CYP9K1_    KDFDHFVNHR IQLDENHDPL ------FGRA LFA-MRDTRW RNMRT----I

CYP9M1     KDFDHFTDHV TQLSLEHDPL ------LARS LFF-TNGARW RHHRS----G

CYP9M2     KDFDHFTDHV TDFRIETDPI ------LARS LFF-TNGAHW RQHRS----G

CYP329A1   PNMSHFESHG YFLDEEKDRF ------LGCQ LHL VNGAEK TTKMAS---F

 

CYP325H1   LNASFSP-AA LKSFVPTLNA KADQFTRELA GKVSG----- ------ECFD

CYP325E1   LNPTFNT-RI LNSFIPIFTD CVAKMIANME KHAGDEK--- -------PIN

CYP325K1   LNSTFNA-RI LESFVPIFND CTQRLVGRLD RYARSGD--- -------RCN

CYP325D2   MSPAFST-SK VTNALPLFVM CAENLMSKLE AMVANDS--- -------TVS

CYP325C2   LNPTFNT-RI LNSFIPVFVQ CARQMVQHME QSVGDVG--- ------RSIS

CYP325D1   MSPAFST-SK VTNALPLFVM CAENMMSKLE AMVANDS--- -------TVS

CYP325C1   LNPTFNT-RI LNSFIPVFVQ CARQMVQHME QSVGDLG--- ------RSIS

CYP325C3   LNPTFNT-RI LNSFIPVFVQ CSRQMVQHME QSVGDVG--- ------RSIS

CYP325A3   LNPAFNQ-RI LISFISIFNR CSEVMVARMA KEADRR---- ------QPFD

CYP325A2   LNPAFNQ-RI LISFISIFNR CSEVMVARMA KEADRR---- ------QPFD

CYP325J1   IQPSFNQ-SI LRGFIPLFVQ KTDAMMRGLG EMAEKG---- ------QPFD

CYP325B1   LNTSFNK-RI LDSFLPLFDK CARKMVNAIK QEADLS---- -------RVD

CYP325A1   LNPAFNQ-RI LISFISIFNR CSEVMVSRMA KEADRR---- ------QPFD

CYP325G1   LSPCFNA-KI LASFVAIFNA KSTILVEQLM GYVKRG---- ------ALFN

CYP325F1   LNRSFSP-MM LSSFVDIFNK KDLVLVENLR KFVGA----- ------GVFN

CYP325F2   LNRSFSP-TM LSSFVDIFND KDFIMVENLR KFVGN----- ------GEVD

CYP4H15_   ITPTFHF-KI LEDFLVIMNH QTDVLIEKLK QNANS----- ------TDFD

CYP4H25_50 ITPTFHF-KI LEDFLVIMNH QTDVLIEKLK QNANS----- ------TDFD

CYP4H26_   INPGFNY-RM LQGFLPTMDA QAAVLVAKLA PHAGG----- ------PAID

CYP4H27v1  ITPAFHF-KI LEDFLVIMNH QSDVLIEKLK TSANG----- ------TDCN

CYP4H30v2  ITPAFHF-KI LEDFLVIMNH QSDVLIEKLK TSANG----- ------TDCN

CYP4H19_   ITPTFHF-KI LESFVTVFNR EAELLIEKLG QNADAG---- ------REFD

CYP4H24_50 ITPTFHF-KI LESFVTVFNQ EAEILIEKLS QNADTG---- ------REFD

CYP4H14    ITPTFHF-KI LEQFVRVFNT ETDTMVQLLR KHVGG----- ------KEFD

CYP4H16    ITPSFHF-KI LDQFMDVFNQ EADTLVSKLE RHVDQ----- ------QEFD

CYP4H18    ITPAFHF-KI LDQFIDVFNE EADVLISKLQ KHVGK----- ------GEFD

CYP4H17    ITPAFHF-KI LDQFMDVFNH EADVLVSKLE KRVNQ----- ------GEFD

CYP4C26_   LTPAFHF-KI LSDFVTIFQN QADVLIDKLA EHTVQG---- ------EPFN

CYP4C37    LTPTFHF-RI LADFVEVFNK QATVLVEKLA KELDNE---- ------AGFD

CYP4C25_   LTPAFHF-KI LDDFVDIFQE QSAVLKRLEA -ELGNE---- ------QGFN

CYP4C28    LTPTFHF-KI LANFVEVMNK QSYVLVRQLE KQLNNT---- ------EGFD

CYP4K2     ITPGFHF-KI LENFVPVFNR QAEAFCAKLE TLTGRSA--- ------DAVN

CYP4AR1    LTGAFHF-KI LDTYVPVFEE QADVLVRKLL DAGG------ ------ATVD

CYP4D15    ITPTFHF-KI LEEFMDIFDQ QGNTFVDILH LFAKSG---- ------ETFD

CYP4D17_   ITPTFHF-KI LEQFVEIFDR QSSTFIKVLE PFAASG---- ------KSFD

CYP4D16_   ITPTFHF-KI LEQFVEIFDQ QSSTFVQVLA AHAKSG---- ------DTFD

CYP4D22    LTPAFHF-KI LDQFIEVFHK QSSILADRLR PEAN-G---- ------QLVN

CYP4AA1    IQPSFNI-AI LEKFIDTFTD SASFLIDKLP KE-E------ ------TVLN

CYP4C35    ITPTFHF-NI LDGFCEVFAE NGAVLVERLQ RHANTG---- ------QPVN

CYP4C36    ITPTFHF-NI LDGFCEVFAE HGALLVEKLA TARAATS--- ----ASQPIN

CYP4C27    ITPTFHF-NI LDGFCDVFAE NSEEMVEYLR PHADTG---- ------KPVN

CYP4G16_   IAPTFHL-NV LKSFIDLFNE NSRLVVKKMQ KENG------ ------KVFD

CYP4G17_   IAPAFHQ-NV LKTFIDVFND NSLAVVKRMS KEVG------ ------HVFD

CYP4J9     LTPAFHF-NI LPSFLLTFQE ECRRLVAQIG QYAD------ ----KGAPVA

CYP4J5     LTPTFHF-NI LNGFHRTFCE ESEKLAAKID SKWDGCEG-- ----AAVEIE

CYP4J10    LTPAFHF-NI LPKFLTIFQE ESEQLVRRLD RLAD------ ----GVQDVV

CYP304B1   YLRDYGFGRR FAQHEAEVNS ELLVLIDLLR YGPKHGHERA IVRD-DGYAK

CYP304C1   TLHEYGFGRR SDAVEQDLVA GLAELIALLK DGPVHEHERA VVDASTGSAL

CYP307A1   HCSPSDASSY YQKMSDVGVM EMHRFMDQLD EVVCPG---- ------KDFK

CYP307B1   HTFPRNYSGR FDELNTIVVD EIG----QML GSVQHG---- ------TTVA

CYP306A1   WLRKLGMVKY GCARLNLERR INSGLIEMLQ DIDNMVDKAP ------QGLN

CYP15B1    TMKQLGMGRN --DFVRVIER EVQELVENFH RRAVKG---- ------ETFP

CYP305A4   HLRQVGYGRQ --AMHEQIQT ELTELLDVLD TRAEQP---- --------LW

CYP305A2   HLRQVGYGRQ --PMQVQIQN ELNELIDVIR ERHQQP---- --------IW

CYP305A3v1 HLRQVGYGRQ --AMHEQIQT ELTELLDVLD TRAEQP---- --------LW

CYP303A1   HLKEFGFARK --GMTEIIQN EAAHIRKDFE EQIAKGQG-- -----KATVQ

CYP301A1   VQKPVLQLST VRRYVSPLEQ VTEEFIDRCQ QLLDDRK--- -----ELPDD

CYP49A1    VQQVMLQPST AKKYIAPLDE ISSDFMDRIQ EMRDENN--- -----ELPGD

CYP12F4    VNPIMMQPKV IRQYVDKVDT VAREFMAIVH GLRDEKQ--- -----ELPAD

CYP12F3    CNPVLLNPKT VKVYVEQMDA VSLEFMEIMA NLRDEKN--- -----ELPAD

CYP12F2    VNPVMMQPKT IKLYVDQVDE IAREFMTLVA GMRDEKN--- -----EVPKD

CYP12F1    VNPVMMQPKI IRLYVDQVDA VAREFMTIVA ELRDAKC--- -----EVPAD

CYP314A1   LTTGITSRRV LQAFIPSVNE ICDDFVDLVR RQRADDG--- ------TIRN

CYP315A1_  NKPMLKDFHW MEEPIRGTCE ATVGHMQQTC DSAA------ ------AFEG

CYP302A1   LQKGLSSPQN VRNFLPATDK ITKEFVTRLR AQMEPGKS-- -----ILIED

CYP6AK1    LSPSVTS-AK LKRMQPLIEQ VGADMMASLD ALPVLRPN-- -----VRETE

CYP6Z3     LTPTFTS-GQ LRQMMPTFLD VSEKLLAELE PLAAEG---- ------RVVD

CYP6Z4     LTPTFTS-GQ LRNMLPTLLD VGNKLIDRMN KVADEK---- ------AIVD

CYP6Z2     LTPTFTS-GQ LRNMLPTLLD VGNKLIDRMN KVADEK---- ------AIVD

CYP6Z1     LTPTFTS-GQ LRHMLPTFLA VGSKLEQYLE RLANEK---- ------QIVD

CYP6AF1    LSPAFTT-GR IRAMFPILRQ VADNFAHFLR TEVDGK---- ------AELD

CYP6AF2    LSPAFTT-GR IRAMFPILRQ VADNFAHFLR TEVDGK---- ------AELD

CYP6AH1    MTSVFTM-NR IRATFPLVQQ VAQDFVQFIE RTRKMD---- ------PHFE

CYP6AJ1    LTPSFTG-AK IKQLFPVMES VADAFVTFIG RHVAQ----- -------ELE

CYP6AG2    ITPGFTN-NR IKAMAHLMDE VCEHMTDYLR TQAKSSDG-- -----VATLD

CYP6AG1    VTPAFTT-SR MKALFPFVED VSNRMKQYIA QHTTKG---- -------PIE

CYP6S2     LTPTFTS-GK LKAMFHTIVD VANRLDQHLG ERCVRM---- ------QRID

CYP6S1     LAPTFTS-GK LKAMFHTIVD VGNRLDQHLA EKCQQV---- ------KRID

CYP6R1     SSPIFST-GR LRAFLPDMVQ MIDQFQAYLD AKLAAEG--- ------EMIE

CYP6N2     LIPTFSS-GK MKMMCPTIVS VGGQFRECLE RCIAHSD--- ------GEVE

CYP6Y2     ITPTFTS-GR MKAAFPLVLG IAEQFCGFLR EQYTSD---- ------DVVE

CYP6Y1     LSPTFTS-GR IKMTLPLITQ VCERFCEHLN ESLQSS---- ------DEIE

CYP6M1     MTPTFTS-GK MKMMFPTVVA AGQQLRDFME ENVQKH---- ------GEME

CYP6N1v2   LTPTFTS-GK MKLMFSTVTA VAEEFDRCMS DEVKIN---- ------PVVE

CYP6M2     LSPTFTS-GK MKMMFPTIVT AGKQFKDFME ETVLRE---- ------NEFE

CYP6M3     LSPTFTS-GK MKMMFSTIVA AGKQFKDFME ETVHEQ---- ------VDFE

CYP6M4     ITPTFTS-GK MKMMFPTVAA AGKQFKDYLE DAIGEQ---- ------EEFE

CYP6AA1    LSPTFTS-GK IKLMFSTICE IGDEFLATVN RFVERD---- ------EPLD

CYP6AA2    LSPTFTS-GK IKSMFFTIRE IGDELLACFD KYIDCG---- ------DPID

CYP6P3     LTPTFTS-GR MKQMFGTIWD VGIELEKCME QSYNQP---- -------EVE

CYP6P5     LTPTFTS-GR MKQMFGTIWA VALELEKYME ENYNQP---- -------EVE

CYP6P4_    LTPTFTS-GR MKQMFGTIQQ VAGEFLKYMN EHCHR----- -------EIE

CYP6P1_    LTPTFTS-GR MKQMFGTMLQ VATELHRHLL EQIDR----- -------ELE

CYP6P2_    LTPTFTS-GK MKQMFATVLE VAERLGQHVA THTG------ -------QME

CYP6AD1    LRPALGS-SS VRTMFATTAR IAQTLVVYIG AQSRRR---- -------DLE

CYP9J3     LSPAFTG-SK MRLMFALIAD CGKSMVEHFR EEDKKARAAG G---TGYQLE

CYP9J4     LSPAFTG-SK MRQMFELMSD SCQGMVEHLL KEAREDES-- -----KQAHE

CYP9L3     LSPTFTG-SK MRQMFAMIVE CSENMVQALA TAN------- -----GQECE

CYP9L2     LSPAFTG-SK MRQMFTMIVE CSENMIKELA TFT------- -----GQEFE

CYP9L1     LSPTFTG-SK MRQMFAMILE CSDNMVQALA HPT------- -----GRECE

CYP9J5     LSPAFTG-SK MRQMFELIVE CSSNMAQHYK EQIRSNGAG- -----SREHE

CYP9K1_    LSPAFTG-SK MRLMFGLITS YCDGAVRTIR SELGADG--- -----TAELE

CYP9M1     LSPAFTG-SK IRNMFVLLSK SAGDAMKRLV VFARGK---- -----PFAME

CYP9M2     LSPAFTG-SK MRSMFGLLSK SAGDAMGRLL VFAAGK---- -----PFTME

CYP329A1   LSPIFRT-PK VPCSMDVTTR RCCAALTDFI ASRVEL---- -------ELE

 

CYP325H1   VHKLLARYTL VTISSTTLGA DLSVEKREV- --LEEYTSNA IQMFT-----

CYP325E1   VLEFTSPCTL EMICRTSLGG KVLER--EG- --KQEFIEGL EIILH-----

CYP325K1   ILEYISACTL EMISRTSLGG KVLER--EG- --AEQFIANL EVALK-----

CYP325D2   LAPVLSECLL NVIFSTTLGA NVVEE--RE- --AKHILNNL DILFQ-----

CYP325C2   IFPFISKCTL EMVCGTTIGC DVMEQ--PG- --KETFIENV DRCFE-----

CYP325D1   LAPVLSECLL NVIFSTTLGA NVVEE--RE- --AKHILNNL DILFQ-----

CYP325C1   IFPCISKCTL EMVCGTTIGC DVMEQ--PG- --KETFIENV DRWFE-----

CYP325C3   IFPFISKCTL EMVCGTTIGC DVMEQ--PG- --KETFIENL DRWFE-----

CYP325A3   VLHYTAQCAL EMVFASSLKS DITDD--AQ- --LHEACEAI QNMCT-----

CYP325A2   ALHYTAQCTF EMVCASSLKS DITHD--PQ- --AREACGAI EKMCA-----

CYP325J1   VYRFTARCTL DMIFATTLGT DMHIQ-DKP- --VCSYLEVL EELFE-----

CYP325B1   VMKHCSRCTL DMVCGSTFGS NILDD--PE- --ANKFVPMI DKAFE-----

CYP325A1   ALHYTAQCTL EMVCASSLKS DITDD--PQ- --AREACGAI EKMCA-----

CYP325G1   VYEYIAKCTL DMVCATTLGT NMQLQ-NEQ- --GDEYIAAI ERASE-----

CYP325F1   SQLYISKCTI DALFENAFGR DIGTQAHDG- --HDEYLQCL DTFLS-----

CYP325F2   LHLYIAKCTI DSIFGTAFGK DLNTQGNDG- --ADEYLHCL DTFFS-----

CYP4H15_   IYEHVTYCAL DIISESAMGV KLNTQQQP-- --NSEYVMAV KEISD-----

CYP4H25_50 IYEHVTYCAL DIISESAMGV KLNTQQQP-- --NSEYVMAV KEVSD-----

CYP4H26_   VDEPLRCMAM DIICETAMGV RLGCQSNP-- --AVPFFKDC EELLD-----

CYP4H27v1  IYNHVTYCAL DIIAESAMSV KLNTQQHP-- --NSEYVLAV KEMTD-----

CYP4H30v2  IYNHVTYCAL DIIAESAMSV KLNTQQHP-- --NSEYVLAV KEMTD-----

CYP4H19_   IYEPISLYAL DSICETSMGV EINAQHNP-- --ENQYVRDV KRMSE-----

CYP4H24_50 IYEPISLYAL DSICTTSMGV EINAQRHP-- --ENQYVRDV KRMSE-----

CYP4H14    IYDYVTLMAL DSICETSMGT TVDAQHNP-- --DNQYVQNV KRMAV-----

CYP4H16    IYDHITLYAL DSICATSMGV HINAQKDP-- --NNEYTQGV KKVSE-----

CYP4H18    IYDYVTLYAL DSICATSMGV RIHAQDDP-- --NNEYAQAV KQMSV-----

CYP4H17    IYDYITLYAL DSICATSMGV QINAQENP-- --NNEYARGV KQMSE-----

CYP4C26_   IVPYVTLCAL DIFCETAMGC PVYAQKNS-- --NSEYVRAH KQIGK-----

CYP4C37    CVRYITLCSL DIICETAMGC PVYAQRQS-- --DSEYVRAH EKIGE-----

CYP4C25_   CFPYVTLCAL DVVCETAMGR QVNAQCNS-- --DSDYVKAV YQIGS-----

CYP4C28    CTIYATLTSL DIICETAMGY PIHALEKS-- --DSEYVKAH EKISE-----

CYP4K2     VFPELKLLTL GIICETAMGV GMDGEGQST- -QQAYYTQIV EELSS-----

CYP4AR1    IFALVKLYTL DVILETSMGV RCRAQLE--- --DSDYVRAV SDLTH-----

CYP4D15    VFPLVTLCAL DVICESAMGT KVNAQMNS-- --ESEYVKAV KEITN-----

CYP4D17_   IFPQVTLCAL DVICESAMGT KVNAQINS-- --TSDYVLAV KEITN-----

CYP4D16_   IFRPVTLCAL DVICETAMGT KVNAQLNT-- --ESEYVQAV KDITN-----

CYP4D22    IYPFVTLAAL DIICETAMGT SINAQTDA-- --DSAYVKAI TELSL-----

CYP4AA1    VTEYVNNCVL DILNEAVLGV PVKSVDKK-- ---EMEQSPF RQGVK-----

CYP4C35    IYPYVTKAAL DVICETAMGV QVHAQTAGE- --DNAYVNAV YELSS-----

CYP4C36    VYPFMTKAAL DIICETAMGV KVNAQTSGM- --DNPYVAAV YDLSS-----

CYP4C27    VYPFIAKAAL DIICETAMGV KVNAQSEGE- --ENDYVKAV CELSR-----

CYP4G16_   CHDYMSECTV EILLETAMGV SKKTQDQS-- --GYDYAMAV MKMCD-----

CYP4G17_   CHDYMSEVTV DILLETAMGS TRTGENKE-- --GFEYAMAV MKMCD-----

CYP4J9     LQPLATKFTL NTICETAMGI KLDSMTMAN- ----EYRSKI EAIGT-----

CYP4J5     LQSAMSQLTL NTICETSMGV KLDALDGAK- ----EYREGI YRVGE-----

CYP4J10    LQPIVTSFAL HTICETAMGV KLDAYREAD- ----EYKQKV YEVGE-----

CYP304B1   CPNVLFSCFA NAFLQIVSGE RLSREETG-- ---VLYDTGA NAMVFQR---

CYP304C1   CPQVFFALFS NVMLRMLTAT RLEREDQA-- ---VLYDVGH CSLAFHR---

CYP307A1   VKPLIMQACA NMFSEYMCSV RFDYNDQGFM SIVRNFDEIF WE--------

CYP307B1   IKPLVLSICA NAFSQYFGSH RFEVEDPRFQ QLVRNFDQIF YE--------

CYP306A1   PSPIIHHVLG NLLNDLVFGI KYEKNNVT-- ---WKYLQHL QEEGV-----

CYP15B1    MSGSMDVALL NVLWVLLAGQ RFELENER-- --LGWLADTV HRTFH-----

CYP305A4   PGSILALSVI NVLWTIVTGS RVAREDDR-- --LQRLLELL QERSK-----

CYP305A2   PGSILSISVI NVLWTFVTGT RIPREDDR-- --LQRLLRLL QDRSK-----

CYP305A3v1 PGSILALSVI NVLWTIVTGS RVAREDDR-- --LQRLLELL QERSK-----

CYP303A1   MQGAFSVYVL NTLWLMMAGV RYSKDNDD-- --LRYLQALL HELFT-----

CYP301A1   FDNEIHKWSL ECIGLVALDT RLGCLEPNLD -PKSEPQQII NAAK------

CYP49A1    FLHELYKWAL ESIGRVALDT RLGCVSKDG- --NDESKRII NSIN------

CYP12F4    FNEWLNRWAF ETMGVLVLDS RLGVLDKD-- -QTPEVTHFI DLTK------

CYP12F3    FNEWLSRWAL ETTGVLALDT RLGVLHST-- -DSGEGQRLV DVVN------

CYP12F2    FDQWLNRWAL ETMGVLALDT RFGVLKDE-- -QTEEAKKIL GLVR------

CYP12F1    FNQWLNRWAL ETMGVLALDT RLGVLRPE-- -QTTGAKAII SLVQ------

CYP314A1   FQDIANSVGL EIICCLVLGR RMGYLTTNR- -QNAKFMRLA EAVK------

CYP315A1_  IEAFLYQWSV EVVLSVMLGS AFTECQQS-- ---AEFRRLV QQFS------

CYP302A1   FMPLVSRLNL ELICLLAFDV RLDSFSEE-- --QMDPGSLS SRLMES----

CYP6AK1    FKELCARFTT DVIASTFFGM QANCLKDE-- --QSEFRYYG RKIF------

CYP6Z3     MRDISSRYVL DVIATVFFGF ETHCLRDP-- --NDPFVEPL RDLN------

CYP6Z4     MRDIASRFVL DTIASVFFGF EANCIHNS-- --EDPFLSTL QRLT------

CYP6Z2     MRDIASRFVL DTIASVFFGF EANCIHNS-- --EDPFLSTL RRAN------

CYP6Z1     MRDIVSRYVL DVVASVFFGF EANCLHDP-- --DDAFRVAL RDLN------

CYP6AF1    MKDCCARMMI DNIGGCAFGI ECNSFHEP-- --DSAFRRTG ELVF------

CYP6AF2    MKDCCARMMI DNIGGCAFGI ECNSFHEP-- --DSAFRRTG ELVF------

CYP6AH1    GKDICAKYTI NVVASVAFGI DAESFTNP-- --NAEFPRMG NALF------

CYP6AJ1    AKEIAARFTT QNVVACTFSI DGDCFGEQ-- --ESEFRRMG RRVF------

CYP6AG2    AKEVMAKYTT DVVASCIFAI DAQSFVKE-- --NPEIRLMG KRIM------

CYP6AG1    TRELCAKYTT DVVSSCIFAA DAQSFTKE-- --KAEIREMG RKLL------

CYP6S2     IKELLARFMT DVIGSCAFGI ECNTLENP-- --NSQFRLMG KRMI------

CYP6S1     VRQLMACFLT DVIGSCAFGI DCNSLENP-- --NSQFRVMG KRMI------

CYP6R1     LKGVLERHNT DIAMRFLLGR EGNNLLAP-- --EGGLHEAV MRGG------

CYP6N2     MKELLARFTT DVIGTCAFGI ECNSLNDP-- --NAEFLRMG RKVF------

CYP6Y2     VRDLMARFTT DVIGSYAFGL ELNSFRDP-- --QNEFRRIG RKHF------

CYP6Y1     VHDLLSRYTI DVIGACAFGI ECNSFREP-- --DNEFRRYG KIAF------

CYP6M1     LKDVMARYTT DVIGTCAFGI ECNSMRDP-- --DAEFRAMG KLFM------

CYP6N1v2   MKDLLARFTT DVIGSVAFGL ECNSLKDP-- --DAKFRVMG RKVF------

CYP6M2     LKDLLARFTT DVIGMCAFGI ECNSMRNP-- --DAEFRAMG RKIF------

CYP6M3     LKDVLARFTT DVIGMCAFGI ECNSMRNP-- --DAEFRVMG RKIF------

CYP6M4     LKELLARYTT DVIGTCAFGI ECNSMRNP-- --NAEFRVMG KKIF------

CYP6AA1    VKLLSQCFTC DVVGSCAFGL QCNSLKNG-- --GSKLLEIG DKVF------

CYP6AA2    IKLLCQCFTC DVVGSCAFGL QCNSLKNG-- --GSKLLEIG DKVF------

CYP6P3     MKDILGRFTT DVIGTCAFGI ECNTLKTT-- --DSEFRKYG NKAF------

CYP6P5     MKDVLGRFTT DVIGTCAFGI ECNTLKTP-- --DSDFRKYG NKAF------

CYP6P4_    MKDVLARFTT DVIGTCAFGI ECNTLKNP-- --DSDFRKYG NKVF------

CYP6P1_    MKAVLARFTT DVIGTCAFGI ECNTLRNP-- --DSDFLKYG RRVF------

CYP6P2_    MKDVLARYTT DVIGTCAFGI ECNTLRNP-- --DSDFLKYG NKVF------

CYP6AD1    WTDLMARYAT DVIGSCAFGI DCRTIRDP-- --GSEFRAMG HRAF------

CYP9J3     MKDVMTRFAN DVIGTAAFGI KVDSFRDP-- --TNVFISMA RSVT------

CYP9J4     MKDIFSRFAN DVIASIAFGI RVNSFADR-- --ENDFYTRG KKLL------

CYP9L3     VKDLFVRFTN DIIASCAFGV RINSFRDK-- --ENVFFRYG KDLT------

CYP9L2     VKNLFIRFTN DVIASCAFGV RINSFRDK-- --ENVFYRYG KDIT------

CYP9L1     VKDLFIRFTN DVIASCAFGV HVNSFRDK-- --DNVFFRYG KDLS------

CYP9J5     MKDVFTRYAN DVIATCAFGI KVDSLKHA-- --ENDFFVNG KKMM------

CYP9K1_    MKELFRRFGN DIVATCAFGI EINSFRDR-- --ANAFFTLG KELT------

CYP9M1     LRDLYSKLGN DAMTSISFGV DVDSLTDP-- --DNEFFLKG KRLA------

CYP9M2     LRDLYSRLGN DVMTSISFGV EVDSLTDR-- --DNEFFLKG KRLA------

CYP329A1   LKAIFVKHTL NLFAGIAFGK ELNTFEEE-- --TDRFCAVA SGMAYG----

 

CYP325H1   NCFERIYKAW LHPD--CVYR MTA-AFREEE VRFKSFKQMS

CYP325E1   NVGLRMFNAN LYPD--IVYR NTR-FYKAEM DARKICYAFT

CYP325K1   TIGVRIFNIF LHID--FIYQ FTA-LYRKEM RAINICQQFT

CYP325D2   MISARAINAL HHID--WVYK HTN-NCKIES ASRAACYSVV

CYP325C2   LVAKRMLNIH HYIE--LVYR-FSR-DCIEES ELRTSCYRFF

CYP325D1   MISARAINAL HHID--WVYK HTN-NCKIES ASRAACYSVV

CYP325C1   LIAKRMVSIH HYIE--LLYR FSR-DFIEES ETRTSCFRFF

CYP325C3   LVAKRMVSIH HYIE--LLYR FSR-DFTEES EHRLACFRFF

CYP325A3   IMSSRMFNVL LYSD--LLFT LTH-KYHELQ KMKVKVERVV

CYP325A2   IMSSRLFNVL LYSD--LLFT LTQ-RYREMQ KVRATLGRVV

CYP325J1   IVTIRAVNLF LHPQ--WLYR WTS-VYRKET KALEEFCRPS

CYP325B1   IIARRVVTVS KYPE--FIYK-LTS-DYKEEM YLRSTFYEYV

CYP325A1   IMSSRLFNVL LYSD--LLFT LTQ-RYREMQ KVRVNLEHVV

CYP325G1   LLNHRLYKVW LHPE--WIYR LTS-GYKVQQ QCYATAYKMS

CYP325F1   LVFKRVLHVE RYIE--CIYR LTK-DYATES SCVNIIRNMS

CYP325F2   LVFKRILHLE RYSE--SIYR LTK-DYEHET NCVNIIRNMS

CYP4H15_   IILKRLFSFL REYK--WAFQ FTK-SHRRQE ELVKIVHDFA

CYP4H25_50 IILKRLFSFL REYK--WAFQ FTK-AHRRQE ELVKIIHSFA

CYP4H26_   LIYKRIFNPL LTYD--LVYA CTR-AGRRAN ATIRALHQFT

CYP4H27v1  IILKRLFSLF REYK--WAFQ FTK-AHRRQR ELVKVIHDFA

CYP4H30v2  IILKRLFSLL REYK--WAFQ FTK-AHRRQR ELVKVIHDFA

CYP4H19_   LVLLRIFHVL SAFP--RTFW YTMPNAWEQR KLIGRLHAFT

CYP4H24_50 LILLRIFHVL SSFP--RTYW YTMPNAWEQR KLIRRLHAFT

CYP4H14    LVLLRTISIV GPYP--TLYN LFHPNAWEQR RVIKQLHAFT

CYP4H16    YVFRRIFSVL NQFP--ALFV LYS-YAREQG RIIKRLHDFT

CYP4H18    FFLRRVFSLL RQFP--SLFF LYP-FAREQG RVIKKLHHFT

CYP4H17    FIFRRVFSVL RQFP--ALFF LYP-FAREQG RVIKKLHDFT

CYP4C26_   VIRNRLQKIW LHPD--FVFK RTK-EFQKHQ ECLKVLHNFS

CYP4C37    IMLNRLQKLW LHPD--IIFR CTR-QYREQQ KCLDILHRFS

CYP4C25_   IVQNRQQKIW LQPD--FIFK LTQ-DYKNHQ KCLAILHEFS

CYP4C28    IILERLQKFW LRSD--FIFR FTK-AYTEHE HCLKILHDFA

CYP4K2     ILYWRMFNVF VNID--AVFR LTR-TSRRFD ELVKKSWQFT

CYP4AR1    ITFWRMYNAM GFSD--WTFR LTK-HYQTYR KSLQINREFT

CYP4D15    LIQLRIYDFV IRYE--FFFR LSA-NRRRQR KALAILHGYT

CYP4D17_   LIQLRFYDFL IRYD--IFFR LSA-NARKQR KVLQVLHSYT

CYP4D16_   LVQIRLFNFL IRYE--IFYR FSA-NRRKQL EALKVLHGYT

CYP4D22    VLTGRFVKVW QRVD--FLFN LSP-DKRRQD RIIKVLHDFT

CYP4AA1    VAPYRITHPW LLFN--SIYK LTD-AATAEL NQKKQLDDFS

CYP4C35    LFLERLVRPW LHPE--WTFR RSA-LGRRQA QLLAILHGYT

CYP4C36    LIQYRLLRPW LHTD--FVWN RTA-EGKRYH EVLAIVHGYA

CYP4C27    LFVERMVRPW LHLD--FIWL RSR-FAARYK NALDTVHNYS

CYP4G16_   ILHLRHRKMW LYPD--LFFN LTQ-YAKKQV KLLNTIHSLT

CYP4G17_   ILHKRQLKIH LRLD--PLFN LTG-VKKEQE RLLQIIHGLT

CYP4J9     MLLQRLMNPW LFED--FTYK LSG-LQGRFE KLLQPVHAFT

CYP4J5     MLLNRAVRPW LYVD--WIYW LLG-YSRQLQ RLLKPLHLFT

CYP4J10    MLVHRTMSPW LYSD--RVYR LLG-YDGPLA KSLKPIHHFT

CYP304B1   EGDDYGTILS YFPTLRYIFP FSRKFQRIRQ ASMNVNGFI-

CYP304C1   QGDDYGLALS YIPWIRHVLP GPSRYRLLRE VNQKANGVI-

CYP307A1   --INQGYAVD FLPWL---AP FYHKHMSKLT RWSAEI----

CYP307B1   --VNQGYAAD FLPFL---LP LHRQNLRRMD RLAEEI----

CYP306A1   KHIGVSMAVN FLPFLRY-LP STRRTINFLL SGKHQTHAIY

CYP15B1    VIDVSGGTLN RFPWLRYVCP ESS-GYGPML RLLKPLWGFL

CYP305A4   VFDMAGGTLN QLPWLRFIAP EWS-GYNLVR RFNKQLTEFF

CYP305A2   AFDMSGGVLC QLPWLRFIAP EWS-GYNLLR RFNLELNEFF

CYP305A3v1 VFDMAGGTLN QLPWLRFIAP EWS-GYNLVR RFNKQLTEFF

CYP303A1   NIDMMGALFS HFPYLRFVAP RLS-GYRQFV EIHECMHKFI

CYP301A1   YALRNVATLE LKAP--YWRY FPTPVWYKYV SNMDYFVKVC

CYP49A1    TFFWTVAEVE LRMP--IWRI YETTAYKNYI GALDTFRELC

CYP12F4    EAVTLFYQLD ILPS--IWRK LKTPAFYRLM RALDELYHLI

CYP12F3    EIFCLTYQLD VLPS--VWKY ISTPKFNRLM KLFDKLTNLI

CYP12F2    NIFELTYKLD VEMS--LWKY ISTPAYRKMM SVFDDLTALI

CYP12F1    KIFDLMYRLE FEPEYVLWKY FQTPSLKLLM QELDNLTNLV

CYP314A1   --ESFVYIGE SYFGLKLWKY VPTRLYSNFV RCEEIIYETI

CYP315A1_  --AVVYDIFR CSSE--LMNI PPAIADRLNV QPWQQFEKVV

CYP302A1   AETTNSCILP TDQGFQLWRY FETPAYRRLR KAQEFMEKTA

CYP6AK1    D-YGPGRGLT MASF--FFLP ELV-PYLRLK LFPRDTEAFL

CYP6Z3     NPNSFVNNIR SAGV--FVCP GLL-KLTGLS SLPPGMRQFA

CYP6Z4     KSRKFMDNFR TSGV--FICP GLL-KLTRIT SLPPELISFV

CYP6Z2     RGRNFIDNFR SSGV--FICP GLL-KLTRMT SLQPELIKFV

CYP6Z1     NPDSFINNIR TAGV--FLCP GLL-KFTGIN SLSPPMKKFT

CYP6AF1    DKPRHS-QVV SSLL--RLYP ALG-HLLGLK VNHDEVVEFF

CYP6AF2    DKPRHS-QVV SSLL--RLYP ALG-HLLGLK VNHDEVVEFF

CYP6AH1    A-PTWLTAIR SQLA--LFAP GLA-KLLRVP FVPGYVDRWF

CYP6AJ1    E-TSPMATVK TMMA--VFLP TVA-KYIPVP FLLKDVDEWI

CYP6AG2    N-FNFVVQLA LLVT--TFFP SVK-KFYKFT FIPKDTEQFF

CYP6AG1    E-PNFQIVMM FLLI--GLIP-ALK-KLIKIS FVSKEIEQFF

CYP6S2     NLPKLK-SLK VFFA--MMFR KQA-QALGIR YNDKDVADFF

CYP6S1     NLPKLK-ALK VFFA--MMFR KQA-RALGIR FNDEDVSDFF

CYP6R1     FLLPS--VWK LFLM--TSYR AVA-RKLRLK VCSRELRETV

CYP6N2     EVPRGR-ILK FFFM--ATFK DFS-RRIHIK GTAEDVSQFF

CYP6Y2     DTPRNH-PLK VFIM--KTFR GLA-NRLGLK LLHDDVAAFF

CYP6Y1     DKLRHS-PLV VYLM--KAFR AHA-NALGMK QLHDDVSGFF

CYP6M1     ERQPS--QFV NMMV--QFSP KLS-RLLGIR FIDKEVSTFF

CYP6N1v2   QASPYR-ALK IFLA--AQFP EIA-RALHVK LTQPDVSDFF

CYP6M2     EISPG--TFK TMMM--NGMP ELA-KMLRMT QTDKDVSDFF

CYP6M3     SKPRG--KVK SLVI--NSMP RLA-KLIGLR TLDPEVSDFF

CYP6M4     GRSRS--NLQ LLLM--NAFP SVA-KLVGIK LILPEVSDFF

CYP6AA1    KPPAWR-NML AFAL--ISFK KLA-KRLRLP VLPGEVTSFF

CYP6AA2    RASPMR-MVY SMAI--GIFP RLS-RALRLP ALPGDVSAFF

CYP6P3     ELNTMI-MMK TFLA--SSYP TLV-RNLHMK ITYNDVERFF

CYP6P5     ELDPIT-LTK FFFA--TSYP QLA-RKLHVR TTQQDVEDFF

CYP6P4_    EQDTLL-MLK FMFA--TTFK GLA-KRIGMK LTDEGVERFF

CYP6P1_    EHRMLA-MVK MTFA--MLFR AQA-VKLGVK VTDDDLEAFF

CYP6P2_    EQKVST-MIK IILV--LMGR KIS-SKFTLK ITDADVETFF

CYP6AD1    RCSLRR-MWK LRFG--YACR RVA-DAMRLC VSEPSVEQFF

CYP9J3     NQESLVKVLK MIGY--TFAP KLM-TRLNID FLTPEEDQFF

CYP9J4     DFSSFWPTIR FMLF--MMVP RVM-LKLDIE LMDKEMCRHF

CYP9L3     DFGRLKVFLK MMGY--QMFP KLM-ARLEID IFDRKHIQFF

CYP9L2     NFGRLKVFLK MMGY--QLIP KLM-AWLEID IFDREHVQFF

CYP9L1     NFSRLKVALK IMGY--QVFP KLM-AQLQMD IFDSTHVQFF

CYP9J5     AFNRPIVMLR MMGF--RLLP KLM-NFFNLD LFDREQRVFF

CYP9K1_    N-LDGVQGLK FLAF--SSFP RVM-RALRLR LFSAKMTSFF

CYP9M1     Q-IDGLPGLK LLMT--TILP GLF-KFLRLG VLYKDVNEFY

CYP9M2     Q-IDGLPGLK FLMA--TTIP RVF-HFFRLS GMYKDVNEFY

CYP329A1   TNPVQVIKTM AFYLMPGFMR TVGVQFTDRE EMDYLVKQYH

 

CYP325H1   RKIITMRQAL LSETKQTKTE YQQ------- ---------- ----------

CYP325E1   DKVIREKRAK FEEKLRNAVD CNNNSTTADE NGNVVF---- ----------

CYP325K1   SKIIQAKREE IGRLCDENSN Q--------- ---------- ----------

CYP325D2   DKVLASRRSA LEN------- ---------- ---------- ----------

CYP325C2   ETVIEKAKAR INS------- ---------- ---------- ----------

CYP325D1   DKVLASRRSA LEN------- ---------- ---------- ----------

CYP325C1   ETVIEKAKAR INS------- ---------- ---------- ----------

CYP325C3   ETVIEKAKAR INS------- ---------- ---------- ----------

CYP325A3   NPILYGRREK LSKQRLENAH S--------- ---------- ----------

CYP325A2   NPILYDRREK ISKQRLENAH S--------- ---------- ----------

CYP325J1   -------KMI LARKATENSH RF-------- ---------- ----------

CYP325B1   YSIINRKRAS LTDENTDKRN EA-------- ---------- ----------

CYP325A1   NPILYGKRER LSKQRLDNAH S--------- ---------- ----------

CYP325G1   RRVLALKGAE LAEIRNRSTV PVAK------ ---------- ----------

CYP325F1   LDLMKEVKEN AHQAQQQPVE EAY------- ---------- ----------

CYP325F2   LDLMKELKEN YKNSKATVKE DAY------- ---------- ----------

CYP4H15_   HNVISERKKQ -LQDEREQQL T--------- -QEK------ ----------

CYP4H25_50 YQVISERKKQ -LEDERERKR T--------- -QEK------ ----------

CYP4H26_   RSVIRERVK- --QMQAVLPN S--------- -QQP------ ----------

CYP4H27v1  YKVISDRKKQ LYSDAQEQQR A--------- -QKQ------ ----------

CYP4H30v2  HKVISDRKK- -QSDAQELQR A--------- -QKH------ ----------

CYP4H19_   DSVIQSRRRQ LLAAVEQGTV GNQET----- ---------- ----------

CYP4H24_50 DTVIHKRREQ LLERSSQ-VS NEQEC----- ---------- ----------

CYP4H14    DNVIRSRREQ LAKEKAQN-V A--------- -FD------- ----------

CYP4H16    NTVIDTRRKQ LARENKP--- ---------- ---------- ----------

CYP4H18    NTVIESRRAQ LEQEQRLGKQ E--------- -FD------- ----------

CYP4H17    NSVINTRRSQ LQAEQAVGKV E--------- -FN------- ----------

CYP4C26_   DRVVRERKEE LRKRKEQLDQ NNNN------ ---------- ----------

CYP4C37    YRMITERRSI IQTGSVVKQA NTED------ ---------- ----------

CYP4C25_   NRVIHERKEE IRRQKQQLGD KNNNNSNNNN GGGGAAGTDQ ----------

CYP4C28    YSMIQKRREM YRQRKQSMLS E--------- -TGS------ ----------

CYP4K2     LGMIERRRKM NELEAPVEVR K--------- ---------- ----------

CYP4AR1    TSVIKQRRAE LLAAGTSDTT R--------- ---------- ----------

CYP4D15    DSVIRTRRQE LNERGAGHN- ---------- --DV------ ----------

CYP4D17_   DSVIKGRRQQ LASIQQSGE- ---------- -QEE------ ----------

CYP4D16_   DSVIKIRREE LNRAAGSGKN T--------- -VVD------ ----------

CYP4D22    TKIIQSRRRE LMEQGGGGGG T--------- -VED------ ----------

CYP4AA1    RKMIRRRREI LKTLSP---- ---------- ---------- ----------

CYP4C35    RKVIQERRRT LDQQHAGERN ---------- -QPE------ ----------

CYP4C36    HKVIRERREE RKQLRTQGKD ---------- -GMA------ ----------

CYP4C27    REVIRDRKAA LESAKKSAG- ---------- -AET------ ----------

CYP4G16_   KKVIRNKKAA FDTGTRGSLA TTSINTVNIE KSKSDSTKTN TVEGLSFGQS

CYP4G17_   RKVVREKKQL YERQMAEGKM PSPSLTEIIG KEEKPGEGQL GGSPAFISQG

CYP4J9     RSIIQQRREL FHQNWLKKLL N--------- ---------- ----------

CYP4J5     ASIIAQRRDL FAQGKLNDLS SS-------- -QDE------ ----------

CYP4J10    RSIIRQRKET FQAAQLTADS ---------- ---------- ----------

CYP304B1   ETIIDK---- YLRTFDEN-- ---------- ---------- ----------

CYP304C1   RSLVEQ---- -CQTYSED-- ---------- ---------- ----------

CYP307A1   RDFILERIVN EREQLGDD-- ---------- ---------- ----------

CYP307B1   RTIILDTIIG DRYERWGEG- ---------- ---------- ----------

CYP306A1   DALISHQRSK LRSCDTFIE- ---------- ---------- ----------

CYP15B1    KETIETIRKN PHCP------ ---------- ---------- ----------

CYP305A4   YPTIEEHKGD FTED------ ---------- ---------- ----------

CYP305A2   APTIAAHHAN FSED------ ---------- ---------- ----------

CYP305A3v1 YPTIEEHKGD FTED------ ---------- ---------- ----------

CYP303A1   GAEVERHQKN FNPD------ ---------- ---------- ----------

CYP301A1   MKYIKNATQR MKLNEGR--- ---------- ---------- ----------

CYP49A1    MRHINIAMEK MNSSTEQ--- ---------- ---------- ----------

CYP12F4    ATRIDEAVIR MEKNPS---- ---------- ---------- ----------

CYP12F3    LDQIERAIVS FEKNP----- ---------- ---------- ----------

CYP12F2    MAKIDEAKQR LEKQP----- ---------- ---------- ----------

CYP12F1    MGKIDEAVRR IEKAP----- ---------- ---------- ----------

CYP314A1   AEIVYEALEE EQLN------ ---------- ---------- ----------

CYP315A1_  PETIRLATAI IEFG------ ---------- ---------- ----------

CYP302A1   VELVSQKLLY FNEDQQRLAS G--------- ---------- ----------

CYP6AK1    KAIIEQEIAR REQTG----- ---------- ---------- ----------

CYP6Z3     TEVVTHQIEH RERHPQ---- ---------- ---------- ----------

CYP6Z4     MEIITHQIDH REKNQ----- ---------- ---------- ----------

CYP6Z2     MEIITHQIDH REKNQ----- ---------- ---------- ----------

CYP6Z1     TEVISSHLHQ RETGQ----- ---------- ---------- ----------

CYP6AF1    TGMMRRTVAM RESSNTAT-- ---------- ---------- ----------

CYP6AF2    TGMMRRTVAM RESSNTAT-- ---------- ---------- ----------

CYP6AH1    RCMVRETIRQ REG------- ---------- ---------- ----------

CYP6AJ1    RSLVANLIIQ RSASEK---- ---------- ---------- ----------

CYP6AG2    IRIMQDAIRY RKENK----- ---------- ---------- ----------

CYP6AG1    TDLMEKAVAY REQNN----- ---------- ---------- ----------

CYP6S2     MNVVRDTIRY RAENG----- ---------- ---------- ----------

CYP6S1     MNVVRDTIRY REEHG----- ---------- ---------- ----------

CYP6R1     ERAVEEAINS KLHEHR---- ---------- ---------- ----------

CYP6N2     FKVVRETIEY REQNN----- ---------- ---------- ----------

CYP6Y2     QSVIRETIHH REGHG----- ---------- ---------- ----------

CYP6Y1     MRVVKDTVEY REREQ----- ---------- ---------- ----------

CYP6M1     LKVVRDTIDY RVKNG----- ---------- ---------- ----------

CYP6N1v2   MGVVKDTIDF RRNNN----- ---------- ---------- ----------

CYP6M2     MNAVRDTINY RVKNN----- ---------- ---------- ----------

CYP6M3     MNAVRDTIKY RVENN----- ---------- ---------- ----------

CYP6M4     MNAVRDTIKY RVENN----- ---------- ---------- ----------

CYP6AA1    MPLVTETVAD RERNS----- ---------- ---------- ----------

CYP6AA2    RPLVQSTVEH RERNA----- ---------- ---------- ----------

CYP6P3     LDIVKETVDY REANN----- ---------- ---------- ----------

CYP6P5     MKIVRETVDY RETNN----- ---------- ---------- ----------

CYP6P4_    LQVVRETVEY REMNN----- ---------- ---------- ----------

CYP6P1_    MNLVHDTVEH RERNG----- ---------- ---------- ----------

CYP6P2_    MNLVRETVEY RERNN----- ---------- ---------- ----------

CYP6AD1    LQLCQSTVLH RESYQ----- ---------- ---------- ----------

CYP9J3     RNTILETMRT RQEKG----- ---------- ---------- ----------

CYP9J4     HAMILDNMKV REEKG----- ---------- ---------- ----------

CYP9L3     TELFRQSVRE REQHG----- ---------- ---------- ----------

CYP9L2     IDLFRQSVQE REQHG----- ---------- ---------- ----------

CYP9L1     TEMFRQSVQE REEHG----- ---------- ---------- ----------

CYP9J5     TEIIKDTVRT RDANG----- ---------- ---------- ----------

CYP9K1_    RHVVMDTITQ REQRG----- ---------- ---------- ----------

CYP9M1     LEAVSTNIRY RERNL----- ---------- ---------- ----------

CYP9M2     TDAVARNIQL RETNR----- ---------- ---------- ----------

CYP329A1   TGASAPNLHS VAR------- ---------- ---------- ----------

 

CYP325H1   -------DSD PEENQELPKA KIFIERLEEI AHDPANG--- ----------

CYP325E1   -------ADE EDDMLSYKKP QIFVDQLLTI PNDGK----- ----------

CYP325K1   -------KLE PEQEHHYRKP QIFIDQLMKM PLTDPSAR-- ----------

CYP325D2   ---------- -EFYEANDSP AMLDRLLSVN EDG------- ----------

CYP325C2   -------TTI EHECEDYKKP LIFADQLLAA QHNGN----- ----------

CYP325D1   ---------- -EFYEANDSP AMLDRLLSVN EDG------- ----------

CYP325C1   -------TAF EDECEDYKKP LIFADQLLAA QHNGN----- ----------

CYP325C3   -------TAI EDECEDYKKP LIFADQLLAA QHNGN----- ----------

CYP325A3   ---------- -EDEEHYRKP MVFLDQLLHM QRGGRD---- ----------

CYP325A2   ---------- -EDEEHYRKP MVFLDQLLHT QRGGRD---- ----------

CYP325J1   ---------- ---------- -SLIEQLQNS AM-------- ----------

CYP325B1   ---------- -DDDIEYRKP QIFVEHLVKG KRAGE----- ----------

CYP325A1   ---------- -EDEEHYRKP MVFLDQLLHT QRGGRD---- ----------

CYP325G1   -------VEA PATTDEYRKP QIYIDQLFRL AKETGV---- ----------

CYP325F1   -------GGK PALN------ --FAHSLSSL AKHNPS---- ----------

CYP325F2   -------ERK PALN------ --FAENLFEL AENNPS---- ----------

CYP4H15_   ---------L EEEDVYGKRR MTLLDLLLNV TIDGK----- ----------

CYP4H25_50 ---------L EEEDVYGKRR MTLLDLLLNV TIDGK----- ----------

CYP4H26_   ---------A PEESQEQQHR STFLDLLLQT RLAGDK---- ----------

CYP4H27v1  ---------L AEEAVYGKRR MTLLDLLLNV TMDGK----- ----------

CYP4H30v2  ---------L AEEDVYGKRR MTLLDLLLNV TMDGK----- ----------

CYP4H19_   ---------H ADDLYGAKQR SSFLDLLLNV TVGGK----- ----------

CYP4H24_50 ---------L DEEHLYTKRR ETFLDLLLNV RVDGN----- ----------

CYP4H14    ---------L NEENLYSKRK LTFLDLLLNV TVEGK----- ----------

CYP4H16    ---------- VQVDDYSKHR DTFLDQLLKV RVNGQ----- ----------

CYP4H18    ---------V NEEDLYSKRR NTFLDQLLKV SIDGK----- ----------

CYP4H17    ---------A DEDELYSKRR DTFLDQLLKV TIDGK----- ----------

CYP4C26_   -GNGESDYSV LEDGIYRKKQ LAFLDLLLEG SG-------- ----------

CYP4C37    ----GLDANN NNCEGTGRKQ LAFLDLLIEA SDGGR----- ----------

CYP4C25_   DGNNNKDDYL SHEELGRKKR LAFLDLLIEA SQDGA----- ----------

CYP4C28    ----ADNAPH SEEAHGQRKQ LAFLDLLLEL SEDGQ----- ----------

CYP4K2     ---------- -EEETFGKQK RALLDTLLEA RIDGR----- ----------

CYP4AR1    ---------- -----PEKGR LSLLDILLRS DITGR----- ----------

CYP4D15    ---------P EEDVLGRKKR MAFLDMLLQS TVDGR----- ----------

CYP4D17_   ---------A SDQDLGIKKR MAFLDMLLQS TIDGR----- ----------

CYP4D16_   ---------E NENELGIKKK MAFLDMLLQS KIDGR----- ----------

CYP4D22    ---------D DMADLGTKRR MAFLDVLLQA TIDGR----- ----------

CYP4AA1    ---------- -------SDR RCLLDFMIEI SNENP----- ----------

CYP4C35    ---------A EGDGLGRRKR LAFLDLLLQS ATTGTGSP-- ----------

CYP4C36    ---------Q DGE---RKRR LAFLDMLLES NEQNN----- ----------

CYP4C27    ---------S DGEAFGVRMR MAFLDLLLEG NQAHN----- ----------

CYP4G16_   SNLKDDLDV- EENDVGEKKR LAFLDLLLES AENGA----- ----------

CYP4G17_   SMLRDDLDDN DENDIGEKRR LAFLDLMIET ANNGA----- ----------

CYP4J9     -------VHI FCRYTNLKQR YAMLDTLLAA EAKEQ----- ----------

CYP4J5     ------DHSL YSTTPGGKKR YAMLDTLLTA EMQGQ----- ----------

CYP4J10    -------TTE ENMYFGSKQR YAMLDTLLAA EAKQQ----- ----------

CYP304B1   ---------- -------HV- RCFLDLYFRE MVKCTP-QE- ----------

CYP304C1   ---------- -------DQ- RCFIDAYIRE LRRTG----- ----------

CYP307A1   ---------- -------DTE RDFADALLKS LRLD------ ----------

CYP307B1   ---------- -------SEP RDYVDSLIEH VKAG------ ----------

CYP306A1   ---------- -------EQE ECILTYFLKE AAKRQEAGRP ----------

CYP15B1    ---------- -------SRR DSLISAFLVE MSRTER---- ----------

CYP305A4   ---------- -------RAV DDLIYAYIKE MRDREGTSN- ----------

CYP305A2   ---------- -------KAN DDLIYGYIKE MRDRQ--DD- ----------

CYP305A3v1 ---------- -------RAV DDLIYAYIKE MRDREGTSN- ----------

CYP303A1   ---------- -------DEP RDLMDVYLHT LQNNNA---- ----------

CYP301A1   ---------- -----ALDGE PSLLERVIKS END------- ----------

CYP49A1    ---------- -----KSEEC ISLVERILQK TNN------- ----------

CYP12F4    ---------- -----ADQDT LSILEKLLKV D--------- ----------

CYP12F3    ---------- -----TTDSN HSALKKLLSI N--------- ----------

CYP12F2    ---------- -----SNSAN QSVLEKLLKI N--------- ----------

CYP12F1    ---------- -----KMEGT QSVLEKLLKT N--------- ----------

CYP314A1   ---------- -------CPD NDVKHIFISI LQTEG----- ----------

CYP315A1_  ---------- -------IAN AQTRDGLLDL MMQK------ ----------

CYP302A1   ---------- ------EHGS KSLMEEYLRN PN-------- ----------

CYP6AK1    ---------- -------ESR GDFIDSMIAL KNNNATLGVN ----------

CYP6Z3     ---------- -------QRR KDFIQLLIDL RREAN--GQ- ----------

CYP6Z4     ---------- -------ITR KDFVQLLIDL RREAENGSE- ----------

CYP6Z2     ---------- -------ITR KDFVQLLIDL RREADKGSE- ----------

CYP6Z1     ---------- -------VTR KDFIQMLTDL RRKAGSSGE- ----------

CYP6AF1    ---------- -------PKR NDLIDMMLQL RAAS---NG- ----------

CYP6AF2    ---------- -------PKR NDLIDMMLQL RAAS---NG- ----------

CYP6AH1    ---------- -------AKR QDLFQVMYDS LSENGTVEAN ----------

CYP6AJ1    ---------- -------TVQ EDLLQSFLKN REKSSTYRID S---------

CYP6AG2    ---------- -------INR TDFLDHLLQL QDRKQITDID ----------

CYP6AG1    ---------- -------VKR VDYLDHLMAL RAKKQLSSLD ----------

CYP6S2     ---------- -------VRR DDFMQLLIDM MQENGAGAG- ----------

CYP6S1     ---------- -------ERR DDFMQLLIDM MKQDGGAEE- ----------

CYP6R1     ---------- -------PEA SRRVDLIDQL VKAPGFDGK- ----------

CYP6N2     ---------- -------IVR NDFMNLLMQL KNSGQLDG-- ----------

CYP6Y2     ---------- -------VRR NDFLDLLIRL KNTGSLEGS- ----------

CYP6Y1     ---------- -------IVR NDFMDLLLKL KNTGRLEAD- ----------

CYP6M1     ---------- -------IQR NDFMDLMIRM LQN--TEN-- ----------

CYP6N1v2   ---------- -------VQR NDFMTLLMKV MKEQIENGEA ----------

CYP6M2     ---------- -------VQR NDFVDLLIKM MSKDGEKS-- ----------

CYP6M3     ---------- -------VQR NDFMDILIRM RSDKETKS-- ----------

CYP6M4     ---------- -------VQR NDFMDILIRM RSDKETKS-- ----------

CYP6AA1    ---------- -------IER PDFLNLLIQL KNKGTVEDET T---------

CYP6AA2    ---------- -------VER PDFLNLLIQL KNKGTVEDEA T---------

CYP6P3     ---------- -------VKR NDFMNLMLQI KNKGKLDDSD D---------

CYP6P5     ---------- -------VQR NDFMNLLLQI KNKGKLDDHG ----------

CYP6P4_    ---------- -------VQR NDFMNLLLQI KNTGSLDGGD ----------

CYP6P1_    ---------- -------VQR NDFLNLLLQI KNKGCLEEQE Q---------

CYP6P2_    ---------- -------VKR NDFLNLLLQI KNTGKLWEGE E---------

CYP6AD1    ---------- -------VVK RDFLQQLLEM KANG------ ----------

CYP9J3     ---------- -------IFR PDMIELLMQA KKGSLKHQQA EEPRTDSETG

CYP9J4     ---------- -------IVR NDMINILMQV KRGALSHR-E ---DEPDVKD

CYP9L3     ---------- -------LVR PDMIHLLTQA GKGKLRYQ-- ---PTDRAEV

CYP9L2     ---------- -------IVR PDMIHLLMQA NNGKLRYQ-- ---PTDHEEV

CYP9L1     ---------- -------IVR PDLIHLLIQA RKGQLRYQ-- ---PQESEET

CYP9J5     ---------- -------IVR PDMVHLLMQA RKGALKHQRD ---TEEREEV

CYP9K1_    ---------- -------IVR HDMINLLMQA RKQELRFD-- ---ENENIET

CYP9M1     ---------- -------IKR PDFIHLLLQA RRNELNSEQ- --TEDDALES

CYP9M2     ---------- -------ITR PDFIHLLLQA RKNTLEAEK- --HEDEALQD

CYP329A1   ---------- ---------- --YLRQANGK MKPSE----- ----------

 

CYP325H1   ---------- ---------- --IDEDGFQQ HIDTMMFGGN ----DTSAQA

CYP325E1   ---------- ---------- -PFTHEEITD HIYTMIAAGN ----ETSATQ

CYP325K1   ---------- ---------- -HFSDEEISD HIYTMIVAGN ----ETSATQ

CYP325D2   ---------- ---------- -PLSDTEIVQ NIYSIVGAGN ----DTTAHS

CYP325C2   ---------- ---------- -PFTDIEVTH NIYSMIAAGN ----DTTALQ

CYP325D1   ---------- ---------- -PLSDTEIVQ NIYSIVGAGN ----DTTAHS

CYP325C1   ---------- ---------- -PFTDIEVKH NIYSMIAAGN ----DTTALQ

CYP325C3   ---------- ---------- -PFTDIEVTH NIYAMIAAGN ----DTTALQ

CYP325A3   ---------- ---------- --LEIQEIEN HLNNIIAAGS ----DTTASQ

CYP325A2   ---------- ---------- --LEIQEIEN HLNTIIGAGS ----ETTANQ

CYP325J1   ---------- ---------- --LDSAAMEQ ELNTIIFAGN ----ETSAMT

CYP325B1   ---------- ---------- -PFPDLEILH HAVTIIVGGN ----DTSALA

CYP325A1   ---------- ---------- --LEMQEIEN HLYTIIGAGS ----ETTANQ

CYP325G1   ---------- ---------- --FDERAIRD EIDTIILGGN ----ETSALT

CYP325F1   ---------- ---------- --LTEDHIKD HIDTMIMAGH ----DTTATT

CYP325F2   ---------- ---------- --LPEDHIKD HIDTMIVAGH ----DTTATT

CYP4H15_   ---------- ---------- -PLSDSDIRE EVDTFMFAGH ----DTTTSC

CYP4H25_50 ---------- ---------- -PLSDSDIRE EVDTFMFAGH ----DTTTSC

CYP4H26_   ---------- ---------- -LLSDDDIRG EVNTFMFAGH ----ETVTSC

CYP4H27v1  ---------- ---------- -PLSDSEIRE EVDTFMFTGH ----DSTTSS

CYP4H30v2  ---------- ---------- -PLSESEIRE EVDTFMFTGH ----DTTTSC

CYP4H19_   ---------- ---------- -PLSDADIRE EVDTFMFEGH ----DTTTSG

CYP4H24_50 ---------- ---------- -SLSDLDIRE EVDTFMFEGH ----DTTTSG

CYP4H14    ---------- ---------- -PLSNLDIRE EVDTFMFEGH ----DTTTSG

CYP4H16    ---------- ---------- -PLSTADIRE EVDTFMFEGH ----DTTTSG

CYP4H18    ---------- ---------- -PLSTADIRE EVDTFMFEGH ----DTTTSG

CYP4H17    ---------- ---------- -PLSTADIRE EVDTFMFEGH ----DTTTSG

CYP4C26_   ---------- ---------- --LSDLAIRE EVDTFIIGGH ----DTTAAA

CYP4C37    ---------- ---------- -ILSDTDIRE EVDTFILGGH ----DTTATS

CYP4C25_   ---------- ---------- -VLSHEDIRE EVDTFMFEGH ----DTTSAA

CYP4C28    ---------- ---------- -LLSDADIRE EVDTFILGGH ----DTTATA

CYP4K2     ---------- ---------- -PLTDEEIRE EVDTFTFAGH ----DTTASA

CYP4AR1    ---------- ---------- -TFSDEEVYS QVNNFMFAGH ----DTTSSA

CYP4D15    ---------- ---------- -PLTDLEIRE EVDTFMFEGH ----DTTTSA

CYP4D17_   ---------- ---------- -PLTDLEIRE EVDTFMFEGH ----DTTTSA

CYP4D16_   ---------- ---------- -PLTDLEIRE EVDTFMFEGH ----DTTTSA

CYP4D22    ---------- ---------- -PLTDREIQE EVDTFMFEGH ----DTTTIA

CYP4AA1    ---------- ---------- -EFTEDDIID EACTFMLAGQ ----DSVGAA

CYP4C35    ---------- ---------- -LLTDEDVRE EVDTFMFEGH ----DTTTAG

CYP4C36    ---------- ---------- -LLTDNDVRE EVDTFMFEGH ----DTTTAG

CYP4C27    ---------- ---------- -IMTDEDVRE EVDTFMFEGH ----DTTTAG

CYP4G16_   ---------- ---------- -LISDEEIKN QVDTIMFEGH ----DTTAAG

CYP4G17_   ---------- ---------- -NISDEEIKE EVDTIMFEGH ----DTTAAG

CYP4J9     ---------- ---------- --IDEDGIRE EVDTFTFEGH ----DTTSAA

CYP4J5     ---------- ---------- --IEPDGIRE EVDTFTFEGH ----DTTGSA

CYP4J10    ---------- ---------- --IDEEGIRE EVDTFMFEGH ----DTTAAA

CYP304B1   ---------- --------PN FTFQHDQLLL GLVDFFFPAI ----SGATTQ

CYP304C1   ---------- --------SK ATSGNDQLII GCADFLVPAF ----SAIPAK

CYP307A1   ---------- ---------- -PSVTRDTIM YMLEDFLGGH ----SAIGNL

CYP307B1   ---------- ---------R GPALEWETAL FALEDIVGGH ----SAVGNF

CYP306A1   ---------- --------DA AFCDDIQLRH LMADLFGAGV ----DTTFTT

CYP15B1    ---------- ---------H ESFTESQLVS LCLDLFQASV ----ETMSSV

CYP305A4   ---------- --------NG SNFTEVQLTM IILDIFIAGG ----QTTSAT

CYP305A2   ---------- --------PQ STFTDLQLTM IILDIFIAGG ----QTTSTT

CYP305A3v1 ---------- --------NG SNFTEVQLTM IILDIFIAGG ----QTTSAT

CYP303A1   ---------- --------PS DSFSREQLLA VCLDMFIAGS ----ETTTKT

CYP301A1   ---------- ---------- ----EKLAVV MALDLILVGI ----DTISMA

CYP49A1    ---------- ---------- ----PKIAAV LALDLIMVGV ----DTTSVA

CYP12F4    ---------- ---------- ----RNAAFT MSMDSLFAGV ----DTTSSG

CYP12F3    ---------- ---------- ----KHVAVI MALDMIFAGI ----DTTSAG

CYP12F2    ---------- ---------- ----KHVAVI MSLDMLIAGI ----DTTSSG

CYP12F1    ---------- ---------- ----KQLAVV MAFDMIMAGI ----DTTSSS

CYP314A1   ---------- ---------- --LDTKEKIS GIIDLITSAI ----ETLSNT

CYP315A1_  ---------- ---------- --LDKPLMMR IFIDFIIAAG ----DTTAFA

CYP302A1   ---------- ---------- --LELNDIIG MASDLLLAGV ----HTTSYT

CYP6AK1    ---------- --------EK IPLKGDILVA QAATFYMASF ----ETTSSV

CYP6Z3     ---------- ---------- DALTIAQCAA NVFLFYVAGA ----DTSTGV

CYP6Z4     ---------- ---------- KALSIEQCAA NVFLFYIAGA ----ETSTAT

CYP6Z2     ---------- ---------- EALTIEQCAA NVFLFYIAGA ----ETSTAT

CYP6Z1     ---------- ---------- ETLTDAQCAA NVFLFYGAGA ----DTSTGT

CYP6AF1    ---------- ---------- SALSMDELMA QAFGFFLAGY ----ETSSSN

CYP6AF2    ---------- ---------- SALSMDELMA QAFGFFLAGY ----ETSSSN

CYP6AH1    ---------- ---------- ----ENHLVG HSVTFLSEGF ----ETSSSM

CYP6AJ1    ---------- --------PF KNATQTEITA HALTIFLEGF ----ETSSVV

CYP6AG2    ---------- ---------- -------IAG HGVSFFADGF ----ETSSIV

CYP6AG1    ---------- ---------- -------MAA HGVTFFIDGF ----ETSSLA

CYP6S2     ---------- ---------- ESLTFEEIAA QAFVFFFGGF ----ETSTTT

CYP6S1     ---------- ---------- DPLKFEEVAA QAFVFFFAGF ----ETSATT

CYP6R1     ---------- ---------- SSLTLSEIAA QVFL-FVAAY ----ETNAIT

CYP6N2     ---------- -----SGEEV GKLSLNEIVA QAFVFFLGGF ----ETSSTT

CYP6Y2     ---------- ------HEIV GRLSGDEIAA QAFIFFTAGF ----ETSSSA

CYP6Y1     ---------- ------GEEI GRLTFEEIAA QAFIFFTAGY ----DTSSTA

CYP6M1     ---------- --------PE EALTFNEVAA QAFVFFFAGF ----ETSSTL

CYP6N1v2   ---------- -----GGDPK DQLTMDDIAA QAFVFFLAGF ----ETSSTA

CYP6M2     ---------- --------DD DSLTFNEIAA QAFVFFLAGF ----ETSSTL

CYP6M3     ---------- --------DD GTLTFNEIAA QAFVFFLAGF ----ETSSTL

CYP6M4     ---------- --------DD GTLTFHEIAA QAFVFFVAGF ----ETSSSL

CYP6AA1    ---------- -------EGL QKLTLDEVAA QAFVFFFAGF ----ETSSTT

CYP6AA2    ---------- -------EEL QKLTLDEVAA QAFVFFFAGF ----ETSSTT

CYP6P3     ---------- --GSLGKGE- VGMTQNELAA QAFVFFLAGF ----ETSSTT

CYP6P5     ---------- --TVVGKGE- VGLTHNELAA QVLIFFLAGF ----ETSSTT

CYP6P4_    ---------- ---VPIKGA- AGLTMNELAA QVFVFFLAGF ----ETSSTT

CYP6P1_    ---------- --EGSASADR TGMTMNELAA QVFIFFVAGF ----ETSSTV

CYP6P2_    ---------- --DHIGKGE- VGMTMNELAA QVFIFFLAGF ----ETSSTT

CYP6AD1    ---------- ---------- -ALDMRQVAG QCYSFFIAGF ----ETSASL

CYP9J3     EGFATVEESH VG--RRA-HD RVWTDTELIA QAFIFFFAGF ----ETISWT

CYP9J4     AGFATVHESA VG--KKA-IT REWTEKELVA QCFLFFLAGF ----DTVSTA

CYP9L3     EGFATVRESN EEKIMPE-NM VKLSESEMVA QCLIFFLAGF ----DTIATL

CYP9L2     EGFATAKESN DEKVVPE-DM VKLSENEMVA QCLIFFLAGF ----DIIASV

CYP9L1     DGFATAKESN EQKILPE-DM VKLSENEMIA QCLLFFLAGF ----DTIATS

CYP9J5     KGFATVEESE VGQTQAS-KG MQMTELEMIA QCLIFFLAGF ----DTVSTC

CYP9K1_    NGGGSQKRS- ---------- VDWTDDDLTA QCTVFFFGGY ----DTVSTL

CYP9M1     AGFSTAETHT VEQRGATGET LQWHDVDITA AAASFFFGGI ----ETTTTV

CYP9M2     AGFSTVKEHT LEQKMGE-GK MNWADIDIAG AAASFFFGGI ----ETTTTL

CYP329A1   ---------- ---------- -QLTDEQLSA QCAMFFTKGF ----EPTLNL

 

CYP325H1   LSNTLLTLGM Y-PDWQEKVY QEIMDVVPHG ---------- PVSYEDLT-K

CYP325E1   AAHACLLLAM H-PEIQDRAA AEICELLAD- DV-------- EYTHETLK-Q

CYP325K1   LAHTCLLLAM H-PHIQTKAY EEVAGLVFSP DQ-------- EITIELMK-D

CYP325D2   LGHTCLFLAM H-PAVQRKLY QELRDVFYSA DE-------- PITEEKLK-Q

CYP325C2   VTHTCLFLAM H-PAIQERVY REVMDVFPDP DQ-------- DIEVEDLK-K

CYP325D1   LGHTCLFLAM H-PAVQRRLY QELRDVFYTA DE-------- PITEEKLK-Q

CYP325C1   VTHTCLFLAM H-PAIQERVY REVMDVFPDP DQ-------- DIEMEDLK-Q

CYP325C3   VTHTCLFLAM H-PAIQERVY REVMDVFPYP DQ-------- DIEVEDLK-K

CYP325A3   VAFILLMLAM H-PKVQDRVH EEIVSIYGSA AP-------- DFSYETIS-A

CYP325A2   VAFILLMLAM H-PEVQERVY EEIVSIYGSA AS-------- DLSYETIS-A

CYP325J1   VANTILLLAM H-PHVQEKLV DEIRLQCGAE GEQ------- SIGYETLN-R

CYP325B1   LCNHLTLLAM H-PKVQEKAR EEIMAVFPTG VEL------- ETTPEALS-Q

CYP325A1   VAFILLMIAM H-PEVQDRVH EEIVSIYGRA AP-------- DFSYETIS-A

CYP325G1   LSHVVLMLAI H-QDVQRRVY EEMVTVVGSS FG-------- EVENDHLA-Q

CYP325F1   IANLLLMLAM H-PEVQEMVY QEVMSVCPDK SK-------- PVTMEDAN-N

CYP325F2   MSNLLLMLAM H-PEVQEMVY QEVMSVCPDK SK-------- PVTMEDVN-N

CYP4H15_   ISFAAYYLSR D-ATVQQRVY DEILAIVGP- DAKTQEL--- --TYGTLQ-E

CYP4H25_50 ISFAAYYLSR D-ATVQQRVY DEILAIVGP- DAKTQEL--- --TYGTLQ-E

CYP4H26_   LSFTLYYLSR Y-PDVQQRLY EEIATMA--- --KAPVL--- --TYGTLM-E

CYP4H27v1  ISFTAYHLSR D-ASIQQRVY DEILAIVGP- DAKTVEL--- --TYGTLQ-K

CYP4H30v2  ISFAAYHLSR D-ASIQQRVY DEILAIVGP- DAKTVEL--- --TYGTLQ-K

CYP4H19_   IAFTFYQLAK H-PEIQEKLH QELQDVLGV- DYRHVPL--- --TYNTLQ-N

CYP4H24_50 IAFTFYQLAK H-PEIQEKLY REIQDVLGG- EYRHVPL--- --TYNTLQ-N

CYP4H14    ISFTIYELAR N-PDVQERVY EEIVSILGK- DHKTAEL--- --TYQNLQ-E

CYP4H16    ISFTILQLAK H-QDVQQKLY EEIDTVLGE- SAKTIVL--- --TNALLQ-E

CYP4H18    ISFTILHLAK H-QDVQQRLY EEIDRMLGE- EKTNVPL--- --TNALLQ-D

CYP4H17    ISFTILQLAK H-QEIQQKLY EEIDGMLGA- EAKSTVL--- --TSALLQ-D

CYP4C26_   MAWILYLLGA A-PDIQERVI QEIDAVMGT- -DRDRRP--- --TMAELN-E

CYP4C37    ISWTLFLLGT D-PTVQERVV QEIECVMGD- -GGERWP--- --TMRELN-E

CYP4C25_   ISWILLLLGT E-PTIQDRIV EEIDQIMGG- -DRERFP--- --TMQELN-E

CYP4C28    LAWMLYLLGT D-QTVQERVF LEIDGIMGG- -DRERHP--- --TMAELS-E

CYP4K2     MTFILYNVAK H-PEIQERVY QEIVNEIGAD FCELSLRAIC LHTLSALN-N

CYP4AR1    ITFILYACAK H-PEVQQRVY EEIVAELPDG E--------- PVTQQRVN-N

CYP4D15    ISFMLHSLAQ N-PDVQEKAF NEVRNIVGD- DRKQ------ PVTMAMLN-D

CYP4D17_   ISFLLHSLAQ N-PTIQEKVF DEVRNVVGD- DRTR------ PVTMAMLN-D

CYP4D16_   ISFLLQNLAK H-PAIQQKVF DEVRNVVGD- DRTR------ PVTIAMLN-D

CYP4D22    ISFTLLLLAR H-PEVQERVY REVVAIVGN- DPAT------ PATHRNLQ-D

CYP4AA1    VAFTLFLLAR H-QDQQAKCY EEIERHIGTD CSK------- PPSAEGIR-E

CYP4C35    MSWALFLLAL H-PEVQERVH QEIDSIFG-- -GSDRPA--- --TMQDLT-A

CYP4C36    MCWALFLLAL H-PDIQHQVH QEIDSIFG-- -GSDRAP--- --TMRDLN-E

CYP4C27    ISWVLFLLAL H-PDVQERVC EEIESIFPP- -GDDRPA--- --TMQDLN-E

CYP4G16_   SSFFLSMMGV H-QQIQDKVI QELDEIFG-- -ESDRPA--- --TFQDTL-E

CYP4G17_   SSFVLCLLGI H-QHVQEQVY AELRQIFG-- -DSKRKA--- --TFGDTL-E

CYP4J9     VIFTLLLLAH S-PDVQQRLY EELQEVAQSR TDADD----- EFTQRDYT-E

CYP4J5     LVFILLTLSW E-LEIQTRLH QELSQLATQN DLTDG----- HLSPNDLN-S

CYP4J10    IMFTLILLAI E-QDVQERCY GELQEVLDRS SSD------- PRSVQDYQ-N

CYP304B1   MALLFERLLH N-PPVIERMQ REIDEVVGH- GR-------- LPTLDDRT-Q

CYP304C1   LGLMLERLVA H-PAVAEKMY TEIDQSVGQ- AR-------- LPGLDDRT-H

CYP307A1   VMLALGYIAK H-PEVGHRIQ REIDRITER- GKR------- NVTLYDTE-S

CYP307B1   LVKAFGYIVQ H-PEVQQRIQ AEADGVLERH GRQ------- VIELTDRA-E

CYP306A1   IRWALLYIAL Y-PTVQKRLR EELRQRLVV- NE-------- PPSLKDVE-A

CYP15B1    LGFAFLYMLH H-PDVMRKVQ QELDTVI-GP DR-------- LPTANDRP-L

CYP305A4   LDLALMMMIV H-PEVQEKVH REIDSQL-EP NA-------- IPHYDDRL-K

CYP305A2   LDLALMMMLV R-PDIQARVR QEIDTTLRS- DE-------- LPQQTDRS-Q

CYP305A3v1 LDLALMMMIV H-PEVQEKVH REIDSQL-EP NA-------- IPHYDDRL-K

CYP303A1   LDFSFLYIVR N-PKVMRRIQ EEIDDVI-GR NR-------- LPTLEDRA-S

CYP301A1   VCSILYQLAT R-PAEQQKLY EELKRLMPDP KT-------- PLTIQLLD-Q

CYP49A1    ATSTIYQLSQ N-PDKQEILF NEIKRSMPSP DT-------- KFTISMLE-T

CYP12F4    STGILYCLAK N-PDKQEKLR AELRKIMPNK DS-------- PLTPDSMK-N

CYP12F3    SVAILYCLAK N-PDKQAKLR AELCTIMPTK DT-------- RLTASMMS-N

CYP12F2    STGVLYCLAK N-PEKQAKLR EELRTILPKK DS-------- PLTAENMH-N

CYP12F1    TFGILYCLAK N-PAKQALLR KELRSILPHH DS-------- PLTPENMR-N

CYP314A1   LSFLLHNLSQ T-VEYQREIA HEFAHCVQH- ---------- -ITNEDLV-S

CYP315A1_  TVWALYLLAS N-ANLQQSVR QDVLDS---- ---------- -----NTL-E

CYP302A1   TAFALYHLGL HGATAQDRLY REAKKILPDP R--------- ---ENRIA-E

CYP6AK1    LSFALYELTK N-PHVQERLR EEIRDIIVKY GR-------- EIPYEAYANE

CYP6Z3     ISFTLHELTH N-GEAMAKAR QEIDHVLERH GG-------- VISYESLQ-E

CYP6Z4     ISFTLHELSH N-PEAMAKLQ QEIDEMMERY NG-------- EITYENIK-E

CYP6Z2     ISFTLHELSH N-PEAMAKLQ QEIDEMMERY NG-------- EITYENIK-E

CYP6Z1     ITFTLHELTH N-AEAMAKLQ QEVDEMMERH HG-------- EITYDNIN-G

CYP6AF1    VTFCLYELAL N-EHCQERAR ACVREALRKH G--------- GLTYEALG-E

CYP6AF2    VTFCLYELAL N-EHCQERAR ACVREALRKH G--------- GLTYEALG-E

CYP6AH1    MSYLLYELAS N-PSIQDRVV KELRTVLEES DG-------- QLTEAALH-K

CYP6AJ1    LGFALYRLAK S-PEVQQNLY NEVKKRIDAN GG-------- QLDFDALQ-Q

CYP6AG2    LTYCLYDLAK Y-PTIQQELR DEIAKAKQVG GG-------- TMSYEQLG-E

CYP6AG1    MCFTLYELAR N-PDCQETLR SELMAARNED G--------- SIDYDALL-E

CYP6S2     LTFALHLLAQ H-PKAQRKAR KCVRSTLAKH GN-------- EMTYEAIK-D

CYP6S1     LTFVLHLLAK H-PEVQLEGR ECVRDVLAKH DN-------- KLSYDAVM-E

CYP6R1     TFYCLYELAQ R-PELQQRAR ACVCEALEKH G--------- GITYEAIA-Q

CYP6N2     MSYCLYELAL N-EAIQQRAR ECVVEAVKTH G--------- GLSYEALM-D

CYP6Y2     MTYTLYELAL N-QEAQRKAR ECVLETLAKH DG-------- VVSYESSK-N

CYP6Y1     MSYTLYELAL N-PEVQERAR ECVKQTLQKY DG-------- KLSYEAVS-E

CYP6M1     LTWTLYELAL N-PEVQEKGR QCVQEVLAKH NG-------- EMTYDAIH-D

CYP6N1v2   MSFCLYELAL N-QELQDKAR QNIAEVLKNY D--------- TISYEAVH-E

CYP6M2     LTWTLYELAL N-PEVQEKGR ECVREILQKH NG-------- EMSYDAVV-E

CYP6M3     LTFTLYELAL N-QEVQDKGR RCVKEVLAKH NG-------- ELTYDAVM-E

CYP6M4     MAFTLYELAL D-QDMQDKAR KCVTDVLERH NG-------- ELTYEAAM-E

CYP6AA1    LSFALFELAN N-PDIQERVR AEMLEKLQLH DG-------- KITYDALK-E

CYP6AA2    LSFALFELAN N-PNIQERVR AEVLEKLQLH DG-------- RITYDALK-E

CYP6P3     QSFCLYELAK N-PDIQERLR EEINRAIAEN GG-------- EVTYDVVM-N

CYP6P5     QSFCLYELAK N-PDIQDRLR EEINRAIEEN GG-------- EVTYDVAM-N

CYP6P4_    MNFCLYELAK N-PDIQDRLR EEIERAVEEN GG-------- EVTYDMVM-N

CYP6P1_    MNFCLYELAK N-PHIQERLR DELNRSIDAN GG-------- ELTYDMVM-G

CYP6P2_    MNFCLYELAK H-PDIQERLR REIERAVEEN GG-------- ELTYDVVM-G

CYP6AD1    LSFCLYELAK H-GAVQDRLR GSIVAALDET DG-------- QLSYDMVM-A

CYP9J3     ISFALYELAV N-EDIQARLY EEVRDAEQSL EEG------K TLTYEQLQ-S

CYP9J4     LGFLMYELMR N-REVQERLY EEIAEIDQRL DGK------- PLTYDAVQ-G

CYP9L3     MSFIVYEITL A-PEIQQRLY EEIQQVSESL GGG------- SVTYDALQ-G

CYP9L2     MTFLLYEVAL D-PEIQQRLY EEIQQVSESL DGK------- SITYDALQ-N

CYP9L1     MTFVLYEVTL A-PEIQQRLY EEIQQVSETL DGK------- ALTYDALQ-G

CYP9J5     LTFLAYELTV N-RDVQDKLY EEILQTDKAL SGG------- PLTYDAVQ-G

CYP9K1_    SAFMAHELAV N-PDVQERLR DEIDRVRSTI GSA------D KLNYETLQ-S

CYP9M1     LCFTSYELAV N-PPIQERLR AEIDSARDEL IDG------A TPTYEILQ-K

CYP9M2     LCFTSYELAV N-PDIQERLR AEIDEQRESL ADG------R TPTYEVLQ-K

CYP329A1   LSFAVYELAQ N-PDVQRKLY EEMHHNGLTT GSATG----- VPPFESIR-T

 

CYP325H1   LTLLEMFLKE TMRLLPITG- LIARTPMKEV QAQ-------

CYP325E1   MEYLERVIKE SQRLCPVAA- VYGRKTIGTI QLD-------

CYP325K1   LHYLECVLKE AMRLMPVAP- IVGRQSRAEI VLD-------

CYP325D2   LSYMECVIKE SLRLAPPGA- TVAREAQEDL TVE-------

CYP325C2   LTYMERVIKE SLRLAPSGP- NIARQTMKDI EIA-------

CYP325D1   LSYMECVIKE SLRLAPPGA- TVAREAQEDL TVE-------

CYP325C1   LTYMERVIKE SLRLAPSGP- YIARQTMKDI EIA-------

CYP325C3   LSYMERVIKE SLRLAPSGP- NIARQTMKDI EIA-------

CYP325A3   QTYLDQVIKE TMRMYPVGP- IIGRQTIETV KLG-------

CYP325A2   QTYLEQVIKE TMRVYPVAP- LIGRETIETV KLG-------

CYP325J1   LTYMELVLKE SLRLLPIAA- VVGRRTTAEV DLG-------

CYP325B1   LPYLERCILE ALRLCPSGP- LLGRVCSEDI EVD-------

CYP325A1   QTYLEQVIKE TMRVYPVAP- LIGRETIETV KLG-------

CYP325G1   LTYMEMVMKE TMRLFPVGP- IIARQCTDDL KIS-------

CYP325F1   LAYTEMVCKE TMRLFPVAP- VIGRKCAADV KLD-------

CYP325F2   LVYTEMVCKE TMRLFPVGP- LIGRKCVADV KLD-------

CYP4H15_   LKYLEMVIKE TLRMNPSVP- IIGRRSAGDM LID-------

CYP4H25_50 LKYLDMVIKE TLRINPSVP- IIGRRSAGDM LID-------

CYP4H26_   LKYTELVIRE TLRLNPSVP- MIGRMAAGDM EID-------

CYP4H27v1  LKYLEMVIKE TLRINPPVP- VIGRRSVGDM VID-------

CYP4H30v2  LKYLEMVIKE TLRVNPPVP- VIGRRSAGDM VID-------

CYP4H19_   FPYLDMVVKE SLRLLPPVS- FIGRRLVEDI QMN-------

CYP4H24_50 FPYLDMVVKE SLRLLPPVS- FIGRRLADDI EMN-------

CYP4H14    FKYLDLVVKE GLRMYPPVG- IIGRALVEDL ELN-------

CYP4H16    LKYLDLVIKE SLRLVPPVP- FVGRKLLEDM EMN-------

CYP4H18    FKYLDMVIKE SLRLVPPVP- IIGRKLLEDM EIN-------

CYP4H17    MKYLDLVVKE SLRLVPPVP- FIGRKLLEDM EMN-------

CYP4C26_   MRYLECCIKE GLRLYPSIP- VIGRRLTEDV RVD-------

CYP4C37    MRYLEACIKE GLRLYPSIP- IIGRRLTEDV RLA-------

CYP4C25_   MKYLEACIKE GLRLYPSVP- LIARRLTEDV DID-------

CYP4C28    MRYLECCIKE SLRLFPSIP- ILSRTLTTGV DIE-------

CYP4K2     LHYMELVIKE SLRLFPPVP- VIARIATEDT ELL-------

CYP4AR1    LKYLEQVIKE SLRMFPPVP- YYSRHIDHDT TQG-------

CYP4D15    MHYLDLVIKE TLRLYPSVP- LFGRKMLQNT EIN-------

CYP4D17_   MHYLDLVIKE TLRLYPSVP- MIGRKMQQTA EIN-------

CYP4D16_   MHYLDLVIKE TLRLYPSVP- MFGRKMMEDA EIN-------

CYP4D22    MKYLELVIKE SLRLYPPVP- IIARRFTENV ELG-------

CYP4AA1    LRHLEACIKE SLRLYPSVP- LMARKIGEDV RVG-------

CYP4C35    MRLLERCLKE TLRLYPSVA- FFGRTTSKDV TLG-------

CYP4C36    MKLLERCLKE TLRLYPSVS- FFGRTLSEDI QFG-------

CYP4C27    LKLLERCIKE ALRLYPSVS- FFGRTLSEDV QLG-------

CYP4G16_   MKYLERCLME TLRMYPPVP- IIARSLKQDL KLAS------

CYP4G17_   MKYLERVIFE TLRMFPPVP- MIARKINEDV QLAS------

CYP4J9     LRYMDMVLKE SLRLYPPVP- FISRNISEDT MFG-------

CYP4J5     AKFFDRVIKE CLRLWPPVA- FISRSVTEEI HLP-------

CYP4J10    LPYLDRVIKE SLRLYPPVA- FISRTTSGEL VVD-------

CYP304B1   LAYTEATLRE AMRIDTLVPS GIAHRVQEDT TLRG------

CYP304C1   LPYCEAVVRE ALRIDTLVPS GIPHVATADT ELAG------

CYP307A1   MPYTVATIFE VLRYSSSP-- IVPHVATEDT CIAG------

CYP307B1   MQYTEAVIME ALRLIASP-- IVPHVANQDS QIGG------

CYP306A1   LPYLRATIAE VQRIRTVVPL GIPHGTTKEI KIGD------

CYP15B1    LPYTEAVILE VERIATVVPG GLVHRAMEEV ELCG------

CYP305A4   LPYVEAFLLE VQRFFSIVPV NGPRRAVVDC TLGR------

CYP305A2   LPYTDAFLLE VQRFFHIVPV SGPRRTLADC SLGG------

CYP305A3v1 LPYVEAFLLE VQRYFSIVPV NGPRRAVADC TLGG------

CYP303A1   MPYSEATTLE GLRLFMSNTF GIPHRALKDT TLCG------

CYP301A1   AHYLKAFIKE VLRVYSTVI- GNGRTLQEDT VICG------

CYP49A1    MPYLRACIKE TLRMYPVVI- GNGRSLQTDA VIGG------

CYP12F4    MPYLRACIKE SLRMYPPTS- GNGRCTGKDL VLQG------

CYP12F3    LPYLRACIKE GMRMFPPAA- GNFRATGRDI VLQG------

CYP12F2    LPYLRACIKE GLRMYQPVA- GNMRAAGRDL VLQG------

CYP12F1    LPYLRACIKE GLRLYQPTP- ANVRNVGHNI VLQG------

CYP314A1   ARFTKACIQE SYRISPTTP- CLARILEEDF QLSG------

CYP315A1_  CGAVKGVVRE TLRLYPIAP- FIGRFVEHES VFGA------

CYP302A1   ASYCRAVLKE TLRLNPISI- GVGRILNRDH VLGG------

CYP6AK1    MPYLGMVISE TNRLYPVLAF IERQCTLPEG STGYKLEP--

CYP6Z3     LAYLDLCVKE TLRKYPGLP- ILNRVCTEDY PVPGAA----

CYP6Z4     MKYLDLCVKE TLRKYPGLP- ILNRECTIDY KVPDS-----

CYP6Z2     MKYLDLCVKE TLRKYPGLP- ILNRECTIDY KVPDS-----

CYP6Z1     MKYLDLCVKE TLRIYPALA- VLNRECTIDY KVPDS-----

CYP6AF1    MEYLDRCINE TLRKYPPLP- LLPRLTSKAY RIPGS-----

CYP6AF2    MEYLDRCINE TLRKYPPLP- LLPRLTSKAY RIPGS-----

CYP6AH1    LVYMEAAMME TLRMHTPVF- TLPRICTQDY ELPPQFPTDT

CYP6AJ1    LEYLDWVMLE TLRMHPPAA- TMHKVCTKKY IMRKGFRDEQ

CYP6AG2    MALLEQIICE SMRIHPLMA- VMAKRCTTDT TLVGPK----

CYP6AG1    LPYLDQVLYE ALRIWPPAA- FLSKVCTVPT ELEVTD----

CYP6S2     MYYLECVIHE TLRLYPPVA- SIHRMTSQPY QLPN------

CYP6S1     MEYLGWIVNE TLRLYPPVA- TLHRITTQPY QLPN------

CYP6R1     MPYLDQCINE TLRKHPLAI- NLIRVVTEDY PVPDST----

CYP6N2     MPYIDQCINE SLRKYPPGA- NLIRQVSQDY RVPGT-----

CYP6Y2     MLYLDQCIYE TLRKYPPVA- ILERIVTKPY RIPDT-----

CYP6Y1     MSYLEQCISE TLRKHPPVA- ILERNADKDY RLPDS-----

CYP6M1     MKYLDQILKE SLRKYPPVP- LHFRMTAQNY RVPDT-----

CYP6N1v2   MKYIEMCINE SLRKYPPAT- TLTRRVEKDY RVAGT-----

CYP6M2     MKYLDQILNE SLRKYPPVP- VHFRVASKDY HVPGT-----

CYP6M3     MNYLDQILKE SLRKYPPVP- VHFRETSKEY QVPGT-----

CYP6M4     MDYLDCVLKE CLRKHPPVS- VHFRITAKDY IVPGT-----

CYP6AA1    MTYLDQVINE TLRMYPPVP- QLIRVTTQPY KVEGA-----

CYP6AA2    MTYLDQVINE TLRLYTPVP- QLFRVTNESY HLPSL-----

CYP6P3     IKYLDNVIDE TLRKYPPVE- SLTRVPSVDY LIPGT-----

CYP6P5     IQYLDNVINE TLRKYPPVE- TLTRKPSSDY VIPGT-----

CYP6P4_    VQYLDNVINE TLRKYPPIE- SLSRVPMRDY TVPGT-----

CYP6P1_    HEYLGQVVNE TLRKYPPLE- TTLRVAGQDY TIPGT-----

CYP6P2_    TEYLNWVVDE TLRKYPPLE- TVTRAPEHDY TVPGT-----

CYP6AD1    LGYLDQVVKE TLRMYPPVD- FLFRVASNDY PIDG------

CYP9J3     LPYLDMVVSE TLRRWPIAT- VLNRECVRNY QYDDGQ----

CYP9J4     MRYMDMVVSE SLRLWPPAP- MVDRYCNRDY TFDDGE----

CYP9L3     MRYLDMVVSE TLRKWPPAP- STDRLCNQDF RITDERD---

CYP9L2     MRYLDMVVSE TLRKWPSQP- ATDRLCNQDY KVTDVTP---

CYP9L1     MRYLDMVVSE TLRKWSPSP- GTDRMCNQDY TIPG------

CYP9J5     MQYMDMVVSE GLRMWAPAP- ATDRLCVRDY VVDDGD----

CYP9K1_    MRYLDMVANE TLRKWTPAP- FLDRTCTKPY MLEDYD----

CYP9M1     MKYLDMVVSE TLRRWAPFG- LTNRRCTKDY TFTNTD----

CYP9M2     MKYLDMVVSE ALRRWTPLG- LTNRKCTKNY TFTNTD----

CYP329A1   LPYLEAIVLE TLRKWPSHP- LLVRECTKPF TIPATENGD-

 

CYP325H1   ---------- -DVTLPVGCF VLIPFLKMHR DKTIWGPDAE TFNPDN

CYP325E1   ---------- -EYVIPKGFI LLLNVFALHR QKEFWGPNAD KFDPDH

CYP325K1   ---------- -GHRIPQGSV FLFHFYALHR RKDVWGPTAD EFEPGR

CYP325D2   ---------- -GQLIPRGTT VVVSLFALHR RKDFWGADAE RFDPDR

CYP325C2   ---------- -GVHIPRDSL IVMSIFSMHR RKDIWGPDAD LFDPDR

CYP325D1   ---------- -GQLIPRGTT VVVSLFALHR RKDFWGADAE RFDPDR

CYP325C1   ---------- -GLHTPRDSL IVMSIFSMHR REDIWGPDAD VFDPDR

CYP325C3   ---------- -GVHIPRDSL IVMSIFSMHR RKDVWGPDAD VFDPDR

CYP325A3   ---------- -DVIVPPGVT LLINILTVHR NKELWGDRAH VFDPDR

CYP325A2   ---------- -DVIVPSGVT LLINILTLHR NKELWGERAH VFDPDR

CYP325J1   ---------- -QYRLPADID IVIDIFDIHR NPAYWGSDAD RFRPER

CYP325B1   ---------- -GNVIPRGTN FLFSIFALHR RTDVWGPDAE GFDPDR

CYP325A1   ---------- -DVIVPSGVT LLINILTLHR NKELWGERAH VFDPDR

CYP325G1   ---------- -TTTIPSGVT VVLGIYNVQR SEQHWGLAAN AFDPDN

CYP325F1   ---------- DKHTIPAGCC VALGIYQIHR DPMIWGPEPG KFNPDH

CYP325F2   ---------- DKHTIPAGCC VALGIYQIHR DPTIWGPEPG KFNPDH

CYP4H15_   ---------- -GVTIPKGMD FGILIYALHN DPELYPEPA- RFDPER

CYP4H25_50 ---------- -GVTIPKGMD FGILIYALHN DPELYPEPA- RFDPER

CYP4H26_   ---------- -GVTIPTGTE VMLNIYVMQN DPQYYPDAD- QFRPER

CYP4H27v1  ---------- -GVTIPKGLD FFIMIYLLHN DPELYPEPT- RFDPER

CYP4H30v2  ---------- -GVTIPKGLD FFIMIYLLHH DPELYPEPT- RFDPER

CYP4H19_   ---------- -GVTIPAGTD FTIPIYVIHR NPAVFPDPE- RFDPER

CYP4H24_50 ---------- -GVTIPAGTD FTIPIYVIHR NPVVYPDPE- RFDPER

CYP4H14    ---------- -GTTVPAGQN VLVPIYVIHR NPEIYPNPN- QFDPSR

CYP4H16    ---------- -GTVVPAGTT ISLNIFCLHR NPEVFPEPE- KFIPER

CYP4H18    ---------- -GAIIPAGTS ISIKIFNIHR NRTVFPEPE- RFDPER

CYP4H17    ---------- -GTTIPAGTT ISLNIFNVHR NPKVFPEPE- KFIPER

CYP4C26_   ---------- -NYTIPAGTT AMIVVYELHR DTSVFSNPD- KFNPDN

CYP4C37    ---------- -DHVLPAGTN AVIVVYQLHR DPAVFPNPD- RFNPDH

CYP4C25_   ---------- -GYVLPAGTT AMIVVYQLHR NPEVFPNPD- KFNPDH

CYP4C28    ---------- -GHHIPSGTN AVIMLYQLHR DPQYFPNPE- KFYPDR

CYP4K2     ---------- -AERITRGTS VAIDIYTMHH SDDYFPDAE- RFDPDR

CYP4AR1    ---------- -GVRLEKGST IVFGTYMLHH NPEYFPEPD- QFRPER

CYP4D15    ---------- -GKIFPAGSN VIVLPFFMGR DPDCFANPE- KFDPER

CYP4D17_   ---------- -GKIIPAGAN LIIMPFFLGR EARYFPEPE- KFDPER

CYP4D16_   ---------- -GKVFPAGSN TIILPFFLGR NPEFFPNPE- KFDPER

CYP4D22    ---------- -GKIVPEGSN FNIGIMHMHR DPTLFPDPE- RFDPER

CYP4AA1    ---------- -KYNLPTGTE IMILPYATHR LEHIYPDPE- RFDPER

CYP4C35    ---------- -GYHVPAGTI VGIHAYNVHR DERFFPDAE- TFDPDR

CYP4C36    ---------- -HYHVPAGTV VGVHAYHVHR DERFFPDAE- KFDPDR

CYP4C27    ---------- -GHQVPAQTI VGIHAYHVHR DERFYPDPE- KFDPDR

CYP4G16_   ---------- SDIVVPAGAT ITVATFKLHR LESIYPNPD- VFNPDN

CYP4G17_   ---------- KNYTIPAGTT VVIGTYKIHR REDLYPHPE- TFNPDN

CYP4J9     ---------- -DRLVPKDTL FNVHIFDLHR DPAVFPDPE- RFDPDR

CYP4J5     ---------- DGRIIPQGCI ANLHIFDLHR DPAQFPDPE- RFDPDR

CYP4J10    ---------- -GTTFPHNTM SHIHIYDLHR DPVQFPDPE- RFDPDR

CYP304B1   ---------- --YDLPKDTL VLIGLDAIHN QREYWGDPE- RFRPER

CYP304C1   ---------- --FQIPKGTL IINGLDYINH QEDVFPEPH- TFRPER

CYP307A1   ---------- --YGVTKGTV VFINNYELNT SERYWSEPK- RFNPSR

CYP307B1   ---------- --YTVAKDTL IFLNNYDLSM SPALWDEPE- RFRPER

CYP306A1   ---------- --FKIPSNTM IMPVVWAVHM NPILFNAPN- TFKPER

CYP15B1    ---------- --YRIPKDAI VMPLLYSLQM DADYWIDPD- VFRPER

CYP305A4   ---------- --YRVPKDTT VLMGLRNVHM DPEHWGDPE- VFRPER

CYP305A2   ---------- --YRVPKDTT VLIGLRTVHM DRDYWGDPE- VFRPER

CYP305A3v1 ---------- --YRVPKDTT VLMGLRNVHM DPKHWGDPE- VFRPER

CYP303A1   ---------- --YHIPKDTM LVGMFRGMML DENLWENPT- QFNPER

CYP301A1   ---------- --YRIPKGVQ CVFPNLVLGT MEEYVSDAQ- RFKPER

CYP49A1    ---------- --YHIPKGTH VIFPHLVVSN LQQYFPEPD- RFVPER

CYP12F4    ---------- --YRVPKGIL VGMGQLVLQR EEGYFTRPS- EFMPER

CYP12F3    ---------- --YRVPSDTD IAMGAQVLLR DEKYFHRPT- EFIPER

CYP12F2    ---------- --YQIPKGTD IAMGTAVLQR SEKYFRRAS- EYLPER

CYP12F1    ---------- --YRIPKGTE VVMGTLALQR DATYFPQPD- AFLPER

CYP314A1   ---------- --YHLQAGTL VLCHTRVACL SEDNFQQAD- RFLPDR

CYP315A1_  ---------- --YALPKDTL VLLSLYSAGR DERFFAEPE- AFNPYR

CYP302A1   ---------- --YQVPRGTV IVTQNMISCR QEAYFRDPQ- LFLPER

CYP6AK1    ---------L HDYVIPNGMP IMIPIYAIHR DPKYFPNPT- VFDPER

CYP6Z3     ---------- -DVVIRAGTQ VIIPLLGISM DEKYFPEPE- VYMPQR

CYP6Z4     ---------- -DVVIRKGTQ VIIPLLSISM NEKYFPDPE- LYSPER

CYP6Z2     ---------- -DVVIRKGTQ VIIPLLSISM NEKYFPDPE- LYSPER

CYP6Z1     ---------- -DTVIRKGTQ MIIPLLGISM NEKYFPEPE- LYSPER

CYP6AF1    ---------- -DVILPAKMR IHLPVYAIQR DERYYPDPD- RFDPDR

CYP6AF2    ---------- -DVILPAKMR IHLPVYAIQR DERYYPDPD- RFDPDR

CYP6AH1    ---------- KRITLRRGTS VIIPVYAIHY DPDIYPMPY- KFDPDR

CYP6AJ1    -------GHD MSIYVREGTP ILIPVLAIHM DPKYYPEPH- QFDPER

CYP6AG2    ---------D RKIFVKKGTT VVLPYYSICF DAEHFADPY- KYDPKR

CYP6AG1    ---------G HKVLIERGLP VMLPVWAVHR DKEYYEEPE- RFNPDR

CYP6S2     ---------- -GEVIPEGVG VIISNLAFQH DPTLFPDPL- AFKPER

CYP6S1     ---------- -GTILPEGVG VILPNLAFHY DPDYFPDPY- DFKPER

CYP6R1     ---------- -GIVLPKGLN IIVPVYAIHY DPQHYPEPE- RFDPDR

CYP6N2     ---------- -DVTFPKGMN VMIPVYAIHH DADNYPDPE- RYDPDR

CYP6Y2     ---------- -SVTLHPGMK IMIPAYAIHH DPDIYPEPA- TYDPDR

CYP6Y1     ---------- -GLLLRRGQK IMIPIYAMHH DPAHFPEPE- QYRPER

CYP6M1     ---------- -DSVIEAGTM LFIPIFSIQR DASLFPEPE- KFDPER

CYP6N1v2   ---------- -DQVLEKGIM VAVPVYALHH DPEHFPNPE- QFDPER

CYP6M2     ---------- -KSVLEAGTA VMIPVHAIHH DPEVFPNPE- QFDPER

CYP6M3     ---------- -KTVLEAGTS VMVPVHAIHR DPEHFPDPE- RFDPDR

CYP6M4     ---------- -NSVLEAGTS VMIPVLGIHH DPEHFPEPE- RFDPER

CYP6AA1    ---------- -NVSLEPDTM LMIPIYAIHH DASIYPDPE- RFDPDR

CYP6AA2    ---------- -NVTLEKGTM VLIPVHSYHH DPALFPEPY- RFDPDR

CYP6P3     ---------- -KHVIPKRTL VQIPAYAIQR DPDHYPDPE- RFNPDR

CYP6P5     ---------- -RHIVPKDTV VQIPIYAIQR DPDHYPDPE- RFDPDR

CYP6P4_    ---------- -KHVIPKDTF IQIPVYALHR DPEFYPEPD- QFNPDR

CYP6P1_    ---------- -RHVIPRHVG VQIPVYAIHH DPAHYPEPE- CFDPDR

CYP6P2_    ---------- -AHVIPKGTM IQIPIYALHH DAQYYPDPE- RFDPER

CYP6AD1    ---------- -FGTIPQGTL LVVPVHALHR DPAYYPQPD- VYNPDR

CYP9J3     ---------G TRFTIEKGTL VFIPVVGIHF DPKYFPEPE- RFDPER

CYP9J4     ---------G LRFKIEKGVT VMVPVAGLHS DPKYFPDPK- RFDPER

CYP9L3     ---------N VEIIIPKGVT VNIPIAGLHH DPRFYPDPD- RFDPER

CYP9L2     ---------N VDIIIPKGCI VSIPIAGLHY DPAIYPDPT- RFDPER

CYP9L1     ---------D PDIVIPKGAT VFIPIAGLHY DPRFYPDPD- RFDPER

CYP9J5     ---------R LKFTIDKGTV VFIPIAGLHH DPQYYPNPS- KFDPER

CYP9K1_    ---------G RRVQLQPGDG LWIPAAAIMR DPQLFPEPD- RFWPER

CYP9M1     ---------G TRVTIEKGLN VSIPLKSFHL DEKFFPDPL- RFDPER

CYP9M2     ---------G SRVTIERGQN ISIPLKYFHL DEKFYPDPL- RFDPER

CYP329A1   ---------R AAIPLKVGDK LYVSVWALHR SGDYYPEPE- RFSPER

 

CYP325H1   FLPERCAQR- ---------- HPYAFIPFSQ GPRNCIGMKY GWLSMKILLC

CYP325E1   FLPERVKAR- ---------- HPYAYLPFSG GPRGCIGSRY AMMSLKIILS

CYP325K1   FLAD--GGR- ---------- HPYAHLPFSG GPRGCIGYRY AMMSLKTLLA

CYP325D2   FLSERCKNR- ---------- MGCAFMPFNT GSRNCIGSRY AMQIMKIILC

CYP325C2   FLPERSEGR- ---------- STNVFIPFSA GSRNCIGGRY AMLSMKVMLS

CYP325D1   FLPERCKNR- ---------- MGCAFMPFNT GSRNCIGSRY AMQIMKIILC

CYP325C1   FLPERSEGR- ---------- SANVFIPFSA GSRNCIGGRY AMLSMKVMLS

CYP325C3   FLPERSEGR- ---------- SANVFIPFSA GARNCIGGRY AMLSMKVTLS

CYP325A3   FDPAQYDAK- --------KQ HPFSYIPFGG GPRNCIGYRY GMLAMKIMVT

CYP325A2   FDPAQYDAK- --------KQ HPFSYIPFGG GPRNCIGYRY GMFAMKIMVT

CYP325J1   FEGLRHD-------------- -PFALLPFSA GSRNCVGLRY AWISMKIMLL

CYP325B1   FLPERSQGR- ---------- HPHAYAPFSM GSRDCIGKRY AIQGMKLVLV

CYP325A1   FDPALYDAK- --------KQ HPFSYIPFGG GPRNCIGYRY GMFAMKIMVT

CYP325G1   FLPERTAHR- ---------- HPYCFLPFSA GPRNCIGYRY GLMSMKVMLC

CYP325F1   FLPERVAER- ---------- HPYAYLPFSG GPRNCIGIRY AWLSMKIMIA

CYP325F2   FLPERVAER- ---------- HPYAYLPFSG GPRNCIGIRY AWLSMKILIA

CYP4H15_   FSEEASEK-- ---------R QPYSYIPFSV GARNCIGQRY AMLEVKTMLV

CYP4H25_50 FSEEASEK-- ---------R QPYSYIPFSV GARNCIGQRY AMLEIKTMLV

CYP4H26_   FLQEP----- ---------- PPYSYLPFST GVRSCIGQRF AMLEMKTVLV

CYP4H27v1  FSEEASVK-- ---------R PPYSYMPFSA GSRNCIGQRY AMLEVKTVLV

CYP4H30v2  FGEEASAK-- ---------R PPFSYMPFSA GSRNCIGQRY AMLEVKTVLV

CYP4H19_   FSDANQHP-- ---------P GPYDYIPFSA GSRNCIGQRY ALLEMKVTVI

CYP4H24_50 FSDGNTQR-- ---------R GPYDYIPFSI GSRNCIGQRY ALLEMKVAIV

CYP4H14    FAEDAESK-- ---------R GPFDYLPFSI GARNCIGQRY ALMEMKVTLI

CYP4H16    FSDANEIP-- ---------R GPYDYIPFSA GSRNCIGQKY ALLEMKVTIV

CYP4H18    FSEANEIK-- ---------R GPYDYIPFSA GSRNCIGQRY ALLEMKVTIV

CYP4H17    FSDANEIK-- ---------R GPYDYIPFSA GFRNCIGQKY ALLEMKVTLV

CYP4C26_   FLPENCHG-- ---------R HPYAYIPFSA GPRNCIGQKF AILEEKSVIS

CYP4C37    FMVDASSSQ- -------EPR HPFAYIPFSA GPRNCIGQKF GALEAKAVLV

CYP4C25_   FLPENCRG-- ---------R HPYAYIPFSA GPRNCIGQKF AVLEEKSIIS

CYP4C28    FLPENSTN-- ---------R HPYSYIPFSA GPRNCIGQKF GALEEKAVIS

CYP4K2     FEGARDAQT- ---------F NPYTYIPFSA GSRNCIGQKF AQYELKSTLV

CYP4AR1    FADG--ETK- ---------R NPFAYIPFSA GSRNCIGQKF ALNELKTALV

CYP4D15    FNVERSAEK- ---------T NPYQYIPFSA GPRNCIGQKF AVTELKSLVS

CYP4D17_   FNVERSAEK- ---------T NPYQYIPFSA GPRNCIGQKF AVAELKSLVS

CYP4D16_   FNVETSAEK- ---------T NPYQYVPFSA GPRNCIGQKF AVAEIKSLVS

CYP4D22    FAPDRTMEQ- ---------S SPYAYVPFSA GPRNCIGQKF AMLELKSTVS

CYP4AA1    FGDGAPHQ-- ---------- NPYAFLPFSA GPRNCIGYKF AYIEMKTVIA

CYP4C35    FLPERTAEN- ---------R HPYAYIPFSA GPRNCIGQKF ALLEEKCLVS

CYP4C36    FLPERTEN-- ---------R HPYAYIPFSA GPRNCIGQKF ALLEEKSVVS

CYP4C27    FLPENTEN-- ---------R HPYAYIPFSA GPRNCIGQKF ALLEEKSIVS

CYP4G16_   FLPEKQAN-- ---------R HYYAFVPFSA GPRSCVGRKY AMLKLKIILS

CYP4G17_   FLPERTQN-- ---------R HYYSYIPFSA GPRSCVGRKY AMLKLKVLLS

CYP4J9     FLPECVAE-- ---------R SPYAYVPFSA GPRNCIGQRF AILELKTVLA

CYP4J5     FLPECVSQ-- ---------R SPYAYIPFSA GPRNCIGQKY ALLEVKTAVA

CYP4J10    FLPEVAEK-- ---------R NPYAYVPFSA GPRNCIGQKF AQLEMKTVLV

CYP304B1   FLDEHG---- ------RLAL AKDLSVPFGA GKRLCAGETF ARNIMFLTLA

CYP304C1   FLSDDGQQQ- ------QLAL EHDRSVPFGA GKRVCAGESF ARNALFLTLT

CYP307A1   ENERTLQIER -------VRK NIPHFLPFSI GKRTCIGQNL VRGFSFIIIA

CYP307B1   FLQQGR---- -------LVK -PDFFIPFGA GRRSCMGYRM TQLLSFSIIA

CYP306A1   FLDLEGRFS- ---------- IPNYFLPFQV GKRMCLGEEL ARNILHLYIA

CYP15B1    FLSVQGD--- -------RVM QHDLFIPFGA GRRRCLGESL AKPAVFLFFS

CYP305A4   FLNEQR---- -------QIV NTERLLPFGQ GKRRCLGETL ARSCLFTFFV

CYP305A2   FLESERDTAG ------KPHL HTDRLMFFGI GKRRCLGEVL ARACLFTFFV

CYP305A3v1 FLDEQR---- -------QIV NTERLLPFGQ GKRRCLGETL ARSCLFTFFV

CYP303A1   FLKDGK---- --------IH IPAQYHPFGV GKHRCMGELM AKSNLFLFLT

CYP301A1   WLKPAQG--- ----GSGDQL HPFASLPYGY GARMCLGRRF ADLEMQILLA

CYP49A1    WLKRGELKEH SGCPHAGQKI HPYVSLPFGY GRRTCIGRRF AECELQILLS

CYP12F4    WLSGEAAAG- ---CPSAKEV HPFVYLPFGF GARSCIGRRL AMMEMEILVC

CYP12F3    WLNDRDAS-- ---IPSAKEV NPFIFLPFGF GSRSCIGKRL AMMEMEVILA

CYP12F2    WLSERPAD-- ---VPSAKDS NPFIFLPFGF GARSCIGKRL AMMELEMITA

CYP12F1    WLPEGQGMG- ---IPSGKEA HPFIFLPFGF GARSCIGKRL SMMEMEIVIA

CYP314A1   WLEQRDENDN --VVNKRAEP GASVVLPFGI GRRMCPGQKV IDIELTLLVA

CYP315A1_  WQRTNAAES- ------STGR TPSASLPFAI GARSCIGQKI AQLQMHYLLS

CYP302A1   WMRETKEP-- ---------V HPHLVLPFGH GMRSCIARRL AEQSMLVLLL

CYP6AK1    FAKEN----- ------LDQI QPCTYMPFGV GPRTCLGSHF GTLQIKIALL

CYP6Z3     FD-EQA---- -------PNY DPDAYYPFGL GPRNCIGLRQ GIMLSKIGLV

CYP6Z4     FD-EAT---- -------KNY DADAYYPFGA GPRNCIGLRQ GVFVSKIGLV

CYP6Z2     FD-EAT---- -------KNY DADAYYPFGA GPRNCIGLRQ GVLVSKIGLV

CYP6Z1     FD-EAT---- -------KNY DADAYYPFGA GPRNCIGLRQ GLLLSKIALV

CYP6AF1    FAPERV---- -------AER HFSAFLPFGE GPRICIGQRL GVLQSRIGLA

CYP6AF2    FAPERV---- -------AER HFSAFLPFGE GPRICIGQRL GVLQSRIGLA

CYP6AH1    FLEENR---- -------KSR PRHAFLGFGE GPRLCLGMKF ALHQSKIGIA

CYP6AJ1    FSPARK---- -------VTH EGATFLPFGE GPRMCLGMRF AQAQVKLAMV

CYP6AG2    FAAENGGSK- -------AYR ERGVYFPFGD GPRMCLGMRF AVTQVRRAIV

CYP6AG1    FSPATGGTK- -------VYR EKGCFLPFGD GPRQCLGMRF ALMQVKRGLF

CYP6S2     FEDKTF---- -------AKT N-PSYLAFGD GPRMCIAMRF GKLQTCLGLA

CYP6S1     FAVKND---- -------FKN N-FSYLPFGE GPRMCIGMRF GLLQTRLGLA

CYP6R1     FTPEAC---- -------RQR APYTFLPFGA GPKICIGYRQ GKLQLRTMLA

CYP6N2     FAPEAC---- -------ESR KPYSFIPFGE GPRICIAARF GMLEARVGLA

CYP6Y2     FTPERM---- -------ARR DPCAYLPFGE GPRICIGLRF GMMQARIGLA

CYP6Y1     FSPDEV---- -------ARR DPYCYLPFGE GPRVCIGMRF GSIQAKLGLA

CYP6M1     FSAEEE---- -------AKR HPFAWTPFGE GPRVCIGLRF GMMQARIGLA

CYP6N1v2   FTAKQS---- -------EKR HPFAFLPFGE GPRICIGLRF GMMQARIGLV

CYP6M2     FSPEQE---- -------AKR HPYAWTPFGE GPRICVGLRF GMMQARIGLA

CYP6M3     FTAEQE---- -------AKR HPYAWTPFGE GPRICIGLRF GMMQARIGLA

CYP6M4     FTAEQE---- -------SKR HPYAWTPFGE GPRICVGPRF GLLQARIGLI

CYP6AA1    FALAAT---- -------HAR HTHAFLPFGD GPRNCIGMRF GLLEVKFGIV

CYP6AA2    FTADAM---- -------KAR HSHAFLPFGD GPRNCIGMRF GLLEVKFGLV

CYP6P3     FLPEEV---- -------KKR HPFTFIPFGE GPRICIGLRF GLMQTKVGLI

CYP6P5     FLPEEV---- -------KKR HPYVFLPFGE GPRICIGLRF GMMQTKVGLI

CYP6P4_    FLPEEV---- -------KKR HPYVFLPFGE GPRICIGLRF GVMQAKIGLI

CYP6P1_    FSAEAC---- -------RNR TPYTFLPFGE GPRVCIGMRF GMMQVKVGLV

CYP6P2_    FRPEVA---- -------NAR PAYVYMPFGE GPRICIGLRF GMMQTKVGLI

CYP6AD1    FAASSKLSG- -------ASK NRPPFMPFGL GPRHCIGDTF GLMLVKVGLV

CYP9J3     FSAANR---- -------NNI QPGTYLPFGA GPRNCIGSRF ALMEAKAALY

CYP9J4     FSEENR---- -------HKI NPGAYLPFGV GPRNCIGSRF ALMEVKSIIY

CYP9L3     FNDENK---- -------HKM PLGAYLPFGI GPRNCIASRF ALMEVKAIVY

CYP9L2     FNDENK---- -------HKI PLGAYLPFGL GPRNCIASRF ALMEVKAIVY

CYP9L1     FNDENK---- -------HKI PLGAYLPFGI GPRNCIASRF ALMEVKAIVY

CYP9J5     FSVENR---- -------DKI NPNTYLPFGI GPRNCIGSRF ALMEVKAIIY

CYP9K1_    FEPESAG--- -------APV DSSAMLAFGL GPRNCIGSRF ALMETKAVFF

CYP9M1     FADPNN---- ---------I NQDAYVPFGT GLRNCIGSRL ALMQAKCFLF

CYP9M2     FADPNN---- ---------I NQDAYVPFGA GLRNCIGSRL ALMQAKCILF

CYP329A1   FVGKDVIN-- --------AA QPSTFIPFGI G-RGCLGQEF VKLMVKATLV

 

CYP325H1   HVVRQYRIST DIKLR----- -D-IKLSLSL VMKLNTKHLI RLEQR-----

CYP325E1   QILKNYRLTT DIPYE----- -K-MDFKFKV SMHLSFEHLV RLERRV----

CYP325K1   QLLRNYELMT DLRYE----- -D-IRYQYQI SLNLAFPHAV RLRRRAV---

CYP325D2   KIVRRYELHA ELTME----- -Q-MQFRFDI ALKQEQGYLI RFERRVESD-

CYP325C2   SILRRLRLRS DLQMN----- -D-LQFRFDL TLKLESEYFV QVEKRM----

CYP325D1   KIVRRYELHT ELTME----- -Q-MQFRFDI ALKQEQGYLI RFERRVESD-

CYP325C1   SILRRLRLRS DLQMN----- -A-LQFRFGL TLKLDSEYFV QVEKRM----

CYP325C3   SILRRLRLRS DLQMN----- -D-LQFRFGL TLKLESEYLV EVEKRM----

CYP325A3   QVLRKYQLST PLTPS----- -DSLRPFFAI TLKIGTGHSI CVKRRTNVLL

CYP325A2   QVLRKYQLST PLTPT----- -DSLRLSFAV TLKVGTGHSI CVKRRAGVVL

CYP325J1   KVLRSYRVDT DLKLE----- -D-LTMKIAL TMKISNGHMV RLKRRQ----

CYP325B1   HLLRSFRFYT DLEYE----- -Q-VEYKFDI TLKLSQGYKF KIQSIDV---

CYP325A1   QVLRKYQLST PLTPT----- -DSLRLSFAV TLKVGTGHSI CVKRRANVVQ

CYP325G1   HLLAAYRFST DLTMD----- -Q-LALKLDI TLKIANKHMV RIVPR-----

CYP325F1   HLVRNYRFKT PLVME----- -D-LVLKFAI VLRITNGCLV SIEDRPSS--

CYP325F2   HLVRNYRFKT TLKME----- -D-LEIKFAI ILRIMNGCLV SIEDRSCSPV

CYP4H15_   KLVANYRFLP CEESN----- -K-LRIKTDM TLKPVNGTFV KIVPR-----

CYP4H25_50 KLVANYQLLP CDERN----- -K-LRIKTDM TLKPVDGAFI KIVPR-----

CYP4H26_   RLLSRFRFVP CGEEN----- -A-LQVKANL TLKPYHGAFV KLVDRH----

CYP4H27v1  KLLANYQLLP CEASN----- -Q-LRLKTDM TLKPVNGVFV KLVRR-----

CYP4H30v2  KLLANYQLLP CEASN----- -Q-LRLKADM TLKPVNGAFV KLVPR-----

CYP4H19_   KMLAHFRVLP GEQMP----- -Q-VRFKTDL VLRPDKGIPI KLVRRKFDSI

CYP4H24_50 RMVSFYRILP GDTMH----- -E-IRLKTDL VLRPDKSIPI KLVARP----

CYP4H14    KLIANYRILP GESLG----- -K-LRVKTDL VLRPDIGIPV KIVLRE----

CYP4H16    KLLASYRILP GESID----- -Q-VRYKADL VIRPSGGIPV KLTRRS----

CYP4H18    KLLASYRILP GESAG----- -R-IRYKTDL VIRPTEGIPV KLLKRTA---

CYP4H17    KLLASYRILP GESID----- -Q-VRYKTDL VLRPTGGIPV KLVKRR----

CYP4C26_   AILRKYRIEA VNRRE----- -D-VQLLCDL VLRPKDGLIV RLHKRE----

CYP4C37    AVLRQYRVEA VDRRE----- -N-LTLYGEL VLRSKDGLRI RITKRK----

CYP4C25_   AVLRRYRVEA VDRRE----- -N-LTLLGEL ILRPKNGLRI RIARRT----

CYP4C28    AVVRNYKIES VHRRE----- -D-LILYGDL VMRTKGGLKI RIQRRI----

CYP4K2     KLLQRFQIRL ADASY----- -V-PILKAEI VLKPAEGLPL RFIKRRV---

CYP4AR1    KILRQCKVEL PDPDF----- -V-PKMKMEL VLKPVNGMQL RFLERKTIQL

CYP4D15    KVLRNYELLP PEQVR----- -E-ETFIAEL ILRPEHGIPI RVKQRVY---

CYP4D17_   KVLRHYEILP PTGKQ----- -D-ESFIAEL ILRPEHGVFV RLKPRAY---

CYP4D16_   KLLRNYEILP PVGRY----- -D-ETFIAEL ILRPEKGIYV RLQPRVY---

CYP4D22    KVIRHFKLTA AGP------- -E-PKLTMQL TLKPRDGLYI GFVPRR----

CYP4AA1    RVLQNFHLSP APGKE----- --EVQPIFRM TLRARGGLWV KMTPRKVVS-

CYP4C35    SILRRFRIRS HRTRA----- -E-QLIVNEL ITRPKDGILL YLEEREW---

CYP4C36    SILRRFTVRS AKTRK----- -E-QLIQHEL ITRPKDGILL YFEPRS----

CYP4C27    SVLRRYRLRS VRTRD----- -E-QKIMHEL ITRPKDGILL YLESRQKKVD

CYP4G16_   TILRNFRVYS DLKEE----- -E-FKLQADI ILKREEGFQI RLEPRQRKSK

CYP4G17_   TVLRHYRVVS NLTEK----- -D-FKLQADI ILKRTDGFQI QLEPRA----

CYP4J9     AILMHFRILP VTKRE----- -E-LVFVADL ILRTKDPIMV RFERR-----

CYP4J5     YLVLRYRILP ATKRE----- -E-IRFIADL VLRSATPLKV RFERRQNA--

CYP4J10    AVLERFRLKP VTRRE----- -E-IVFMADL VLRAKTPLKV RLERR-----

CYP304B1   ALMQNFNIRQ PPNA-----R LPDLSKRNTG VIIAPEDFWL KFEPR-----

CYP304C1   TLVQQFTFSM EG-------R TPDPEQHLTG VIRTAPDFRI KFTAR-----

CYP307A1   NILQKYDVHS NDLS------ --LIKMYPAC VAVPPDTYPL AFTQRSTVAA

CYP307B1   NLLRAYTIAP IAGQ------ --DYRVPVGS LAMPEQSYVF NVTPRSCCC-

CYP306A1   NIVSHYDWIR ISPED----- AMLIDLTGNC GLTLTPPDYI IIFSKNNK--

CYP15B1    AIMHRFEIEC EGKE------ -LPSLNAVDG ITLSPVPYTL RLAERVCR--

CYP305A4   GVMKRFCLVG TDEASEDGTS MAPSLTLKPG ITLSAKPYHV VFQPRRNQKG

CYP305A2   GVMQKFELLK PEGGNRE--- MEPSIVLRPG ITLSPKPYEV VFRPR-----

CYP305A3v1 GVMKRFCLVG TDEGSEDGTS MAPSLTLKPG ITLSAKPYHV VFQPRKRT--

CYP303A1   TTLQSFDLLL PDGAP----- -IPSDIPIDG ATPSVRKYHV AIRARH----

CYP301A1   KLLRSFKLEY HHKP------ ---LKYEVTF MYAPEGALKF KMTPREE---

CYP49A1    KLFRRYQVEY NYEK------ ---LTYKVNP TYIPDKPLKF KLTERTS---

CYP12F4    RMVRKYDVGW NYGE------ ---LKYRATL VNIPANDLKF QLKEVSD---

CYP12F3    RWIRQFEFRW NYED------ ---YKFRTTV INMPGCPLKF EIRDLDD---

CYP12F2    RLVRQFELRW NYDK------ ---LHFKQAL INIPANPLQF ELRDVDH---

CYP12F1    RLVRRYEVGW NYGK------ ---LKVKMGF VTTATVPLQF ELKDVID---

CYP314A1   KIFQNFEIEY RSP------- ---LDTQFQF LLAPRTPIEI RFRDRT----

CYP315A1_  MILTKFELTL AEADQ----- QDAIKPILKM ITVPSAPVKL CLKPCSAQPE

CYP302A1   RLIRSFEIEW AGTVP----- ---MDVKTKL INQPDQPIRL RMKARTS---

CYP6AK1    KLLSQYRIER SPSTP----- EVLTYRKNAF TLNSNEGLYA ALVEDAM---

CYP6Z3     LMLSRFDFEA TVPRK----- --VRFEPANV TLTPDGGLPM KITVRGDRAK

CYP6Z4     LLLSKYNFQA TTPAK----- --VKFAVATV VVTPEDGFPM RVEHRC----

CYP6Z2     FLLSKFKFQA TTPAK----- --VKFAAATV GLTPDAGFPM RIDHRK----

CYP6Z1     MMLSRFNFSA TIPRK----- --IKFEPVSI TLAPKGGLPM RIENRAKH--

CYP6AF1    TVLANFRVRP GPRTP----- IPLVFAKDAV TLQSAGEVYL QVEPLQEHE-

CYP6AF2    TVLANFRVRP GPRTP----- IPLVFAKDAV TLQSAGEVYL QVEPLQEHE-

CYP6AH1    TLLNKYRVKV SSKQE----- LPLEFAKSSF LLNPKSGIWL NFEDRE----

CYP6AJ1    KLILNYRVTV GPN-D----- KPFAIDSRSF VYQARDGLRI VFERR-----

CYP6AG2    EVVERFSISV SSKTI----- EPFEMDPDQF MLMPKGSIWL DFKPIA----

CYP6AG1    EVITKYEVSV NSKSK----- QPIQLDPKAF IVCPLGGIWL DYKPIEA---

CYP6S2     MLLKSYTFSL EDCDVD---- RPLLIDPINL MYGPAGPVWL NVERYVEGSK

CYP6S1     MLLRNYHFTI DPSDAA---- RPLRIDPINL THGPEGQVWL NVERIA----

CYP6R1     VLLSSYEFAT CANTT----- -PGALTNAHT VIKPQGDLWL KVKKLNRVVA

CYP6N2     VLLMHFSFAR CSKTN----- VPLVISSRHA VLTPEGGLWL KVEKLKE---

CYP6Y2     LLLKHFQVLP CKETD----- VPLTYSPRAF VLTPVNGVRL RLVKYDAHGA

CYP6Y1     SLLDRFRFSA CDRTQ----- IPVQYSRTNF ILGPANGVWL RVEVLDA---

CYP6M1     YLLQGFSFAP YEKTS----- IPMKFITNSF ILGPREGLWL KVNKLESKQG

CYP6N1v2   YLLKHFRFTL ANDRMS---- VPLKISSASP ILTIDGGLWL NVERL-----

CYP6M2     YLLDGFRFAP SSKTV----- IPMELSKESF IMAPKGGLWL KVDKI-----

CYP6M3     YLLTGFRFTP SAKTI----- VPMEFDIKSF ILSPAGGLWL KVEKLNS---

CYP6M4     YLLTSFRFVR CSKTP----- VPLRYALKNQ ILSPEAGMWL KLEKLNEV--

CYP6AA1    QMVSKLRFTV SERMQ----- MPLRMSKTAS ILEAEGGIWL NATKL-----

CYP6AA2    QVLNKLRLTV NERTA----- LPLRMSKRSG FPEAEGGIWL NASRL-----

CYP6P3     TLLRKFRFSP SARTP----- ERVEYDPKMI TIAPKAGNYL KVEKL-----

CYP6P5     NLLRRFRFSP SARTP----- ERVVYDPKMF TLSPIGGNYL KVDKIA----

CYP6P4_    TLLRNFRFTP SSQTP----- AKIVFDPKSF ILSPSTGNYL KVDKI-----

CYP6P1_    SMVRAFRFLP TAQTP----- DRIVFDPKSF ILSPAGGNYL RIVQV-----

CYP6P2_    TLLRQFRFSP TEQTP----- DRIRFMPNVF VLSPDSGNYL EVEKL-----

CYP6AD1    AMVRSFRFTL DVDRTP---- ENVTFKPRSL VLAAGSGMYL NVERV-----

CYP9J3     YLLLNFRLVP CAKTQ----- IPLKLKKSST QFATEQGIWL EFQSRSS---

CYP9J4     YLLKSFTFER CEQTQ----- VPLRLKNSPV VLAAEKGIWI RFKPREVAK-

CYP9L3     HLLLHYEFKR TDRTP----- VPVQLAKGFT PLRSEKGIYL QLSPRRTN--

CYP9L2     QLLLNYEFKR SERTP----- VPLKLAKGFA STSAEKGIYL QLSPRQVE--

CYP9L1     HILLNYELKR SERTS----- VPVKLAKGFS PLKPENGMYL KFNPRMKN--

CYP9J5     YMLREFSFER TPNTQ----- VPLRLAKGFA GMRSEKGVFV EFRPRKQAAN

CYP9K1_    FLLTHFLLEA GPRTQ----- HPIRLKKSSL GPCAEKGSWI RFRLRK----

CYP9M1     YMLSNFIIQP GSKLT----- IPLVLDETSA GLNAKHGFWM NLVPR-----

CYP9M2     YMLSNFIIKP DTKLT----- IPIVIDETSA GLNAKHGFWM NLVPRSA---

CYP329A1   ALLQRFKLQP GERTP----- EPLQLIESAS SLEARDGFWI RLEPRL----

 

CYP325H1   ---------- ----

CYP325E1   ---------- ----

CYP325K1   ---------- ----

CYP325D2   ---------- ----

CYP325C2   ---------- ----

CYP325D1   ---------- ----

CYP325C1   ---------- ----

CYP325C3   ---------- ----

CYP325A3   ---------- ----

CYP325A2   ---------- ----

CYP325J1   ---------- ----

CYP325B1   ---------- ----

CYP325A1   ---------- ----

CYP325G1   ---------- ----

CYP325F1   ---------- ----

CYP325F2   ---------- ----

CYP4H15_   ---------- ----

CYP4H25_50 ---------- ----

CYP4H26_   ---------- ----

CYP4H27v1  ---------- ----

CYP4H30v2  ---------- ----

CYP4H19_   K--------- ----

CYP4H24_50 ---------- ----

CYP4H14    ---------- ----

CYP4H16    ---------- ----

CYP4H18    ---------- ----

CYP4H17    ---------- ----

CYP4C26_   ---------- ----

CYP4C37    ---------- ----

CYP4C25_   ---------- ----

CYP4C28    ---------- ----

CYP4K2     ---------- ----

CYP4AR1    ---------- ----

CYP4D15    ---------- ----

CYP4D17_   ---------- ----

CYP4D16_   ---------- ----

CYP4D22    ---------- ----

CYP4AA1    ---------- ----

CYP4C35    ---------- ----

CYP4C36    ---------- ----

CYP4C27    A--------- ----

CYP4G16_   TL-------- ----

CYP4G17_   ---------- ----

CYP4J9     ---------- ----

CYP4J5     ---------- ----

CYP4J10    ---------- ----

CYP304B1   ---------- ----

CYP304C1   ---------- ----

CYP307A1   ---------- ----

CYP307B1   ---------- ----

CYP306A1   ---------- ----

CYP15B1    ---------- ----

CYP305A4   RLQEEIKERI NYAQ

CYP305A2   ---------- ----

CYP305A3v1 ---------- ----

CYP303A1   ---------- ----

CYP301A1   ---------- ----

CYP49A1    ---------- ----

CYP12F4    ---------- ----

CYP12F3    ---------- ----

CYP12F2    ---------- ----

CYP12F1    ---------- ----

CYP314A1   ---------- ----

CYP315A1_  RQAVAQMQD- ----

CYP302A1   ---------- ----

CYP6AK1    ---------- ----

CYP6Z3     VQ-------- ----

CYP6Z4     ---------- ----

CYP6Z2     ---------- ----

CYP6Z1     ---------- ----

CYP6AF1    ---------- ----

CYP6AF2    ---------- ----

CYP6AH1    ---------- ----

CYP6AJ1    ---------- ----

CYP6AG2    ---------- ----

CYP6AG1    ---------- ----

CYP6S2     SS-------- ----

CYP6S1     ---------- ----

CYP6R1     A--------- ----

CYP6N2     ---------- ----

CYP6Y2     AEGN------ ----

CYP6Y1     ---------- ----

CYP6M1     ---------- ----

CYP6N1v2   ---------- ----

CYP6M2     ---------- ----

CYP6M3     ---------- ----

CYP6M4     ---------- ----

CYP6AA1    ---------- ----

CYP6AA2    ---------- ----

CYP6P3     ---------- ----

CYP6P5     ---------- ----

CYP6P4_    ---------- ----

CYP6P1_    ---------- ----

CYP6P2_    ---------- ----

CYP6AD1    ---------- ----

CYP9J3     ---------- ----

CYP9J4     ---------- ----

CYP9L3     ---------- ----

CYP9L2     ---------- ----

CYP9L1     ---------- ----

CYP9J5     ---------- ----

CYP9K1_    ---------- ----

CYP9M1     ---------- ----

CYP9M2     ---------- ----

CYP329A1   ---------- ----