FASTA FILE
OF ALL AEDES P450S (164 seqs, = 11 in the 2 clan, 84 in the 3 clan ,
59
in the 4 clan, 10 in the mito clan )
REVISED 6/25/2006
D. Nelson
CYP2 clan
(11 seqs)
>CYP15B1 1.48_3
MWQNLVVLIIFVILFCLRDMRKPGYFPP
(1)
GPNWFPLIGSGFEVFRLVKHFKFYHLMWAELMRRYGPIVGLRLGRDRVVIVSGLDA
IREVYSKDQFDGRPDGFFFRIRSFDKRLGVVFTDGAHWDIQRRFSVRTLKALGMGRTGMV
NSLEREAEEMIHHLRKLSRTQKVISMHNAFDVSVLNSIWTLIAGKR
(2)
FDLDDKKLEWIMETIHKSFRVIDMSGGVLNQFPPIRYVLPDKSGFAPLLNLLRPLWTFLQ
(0)
GTIKSIRSKLDQPDNPDCFIASYLRELNIAERHSSFTNEQLLCLCLDL
FQAGSETTSNTLGYGIAHMLHHPEIVQKIHNELDSVIGRYRLPLLADRPYLPYTEAVLCE
IQRISNIAPLAIAHRTVAPVQLGTYVIPKNTITLISLYSLHMDKAYWGDPEVFRPERFLN
ETGDKLVAHEYFVPFGS
(1)
GKRRCLGESLAKSSLFLFFTAFMHAFLVEPAEPGKLPELDGIDGITLSPCPYYVQLKERLI*
>CYP18A1 1.133_1
MFLDTYLLGVVRQEFFDASKARST
2678
LLVFCCTLSCVVFLQWLFRLVCQIKKLPPGPWGVPIFGYLTFIGHEKHTQYMKLARKYG 2502
2501
SLFSAKLGAQLTVVISDYKIIREAFKTEDFTGRPHSPLLKTLGGF (1?)
GIINSEGQLWKDQRRFLH
719
718 EKLRHFGMTVLGNKKHLMESRIM (0)
534
TEVAELLASLNEVGSQSTDLSKYLSVSVSNVICNIIMSVRFSLEDPKFKRFNWLIEEGMRLF 359
358 GEIHTIDYIPQIQYLPGNINAKNKIAKNRQEMFDFYREVIDEHKRSFNAENIRDIVDAYL
179
178 DEIQKAQAEGRDQELFDGKDH 116
EIQMMQVIADLFSAGMETIKTTLLWLNVFMLRHPDAMKRVQDELDQVVGRNRLPKIEDVP 406
YLPITETTILEVMRISSIVPLATTHSPKS (2) 319
2116
DVVINGYTIPAGSYVVPLINSVHMDPTLWDKPEEFNPSRFLDAEGKVHKPDFFIPFGVGR 1937
1936
RRCLGDVLARMELFLFFASIMHTFTIELPEDEPMPSLKGIIGVTISPQAFRVKLIPRPLN 1757
1756
ADLDRLRNVGSC* 1718
>CYP303A1ae
MYWYYLACFIVVFIIFLYLDCIKPANFPPGPKWYPIIGSAIEIARARQKTGMLCKAIKLIASKYDHKGVIGF
KVGKDKTVMAISGDSLREMMSNEDLDGRPTGIFYETRTWGLRRGVLLTDEEFWQEQRRFI
VRHLKEFGFARKGMAEIIGNEAEYVKNDFHALVKAGNGKALVQMQSAFSVYILNTLWLMM
AGIRYTRENKDLKYLQSLLHELFANIDMMGALFSHFPFIRFFAPRLSGYKQFVEIHNLMH
KFIGAEVENHKKSFNDTDEPRDLMDVYLKILQSNRDIPESFSQEQLLAVCLDMFIAGSET
TTKTLGFAFLHLVRQRETQLKVQKELDEVVGRNRLPTLEDRVN
(2)
LPYCEAVVLEALRMFMANTFGIPHRALRDTKLCGYDIPK
(0)
DTMLVGMFRGMMLNDWESPTSFKPERFLKGGKIVIPPNFHPFGVGRHRCMGEMMGKAN
110
LFLFITTLFQSFDFLVPEGYPIPSDEPIDGATPSVRQYTALIVPR*
>CYP304B2xx/yy 1.1104_2
22307
MFVTPTIFLWLVTIGLIAYRCHRFLFDRPKNFPDGPPKFPLLGGYAVMLLINFYHLHRAANKLCEYYRTKILGIYLGNFP
TVIVNDFATVKEVLNRVEFDGRPDLFIARMREKNFLLRGIFFTQGPDWKEQRRFILRYLRDYGFGRRFDELEAETNAEIL
TLVEMLRYGPRHEHETEFMTKDGCAMVPNVFFACFANAFLYVLTGERINRDEAGALFE
(2) 22960
35137 TGKYAMMFQRTGDDYGTIYSLL
PWMRHLFPNRTRYRTIREGSLGVNRFIESIIQKRLETHEEGHVRCFLDLYFTEMKKTVPRTEDNRFTFQ
(1) 35409
35466 HDQLVLGIVDF
FFPAISGATTQIALLLERLLWHPEVVQKMQAEIDDVVGHGRLPTLDDRINLPYTEATLREAMRIDTLVPSGVAHMAMKDT
TLRGYDIPKDTILVLGLDSIHMQKDIWGDPERFRPERFLNYRGELSLSKDVSVPFGAGKRLCAGETFARNTMFLIVSALV
QNFNIRQRLGDKLPDMGKRSTGIIISPADYWVKFEPR* 36092
>CYP304B3yy/xx 1.1104_3
46553 MLLNPSAILWTVAAGLLIYRCFRFMFDRPPNFPSGPPRFPLLGSYLVLLMVNYRHLHRAAVRLGQFYRTKILGIYLGDFP
SIVVNDLAIAKEVLARSEFDGRSDLFLARMRERNFQRRGIFFTDGPHWKEQRRFVLRHLRDYGFGRRFDELEAETRSELM
TLLDVLRYGPKFEHERLFAKDGCVKCPDAFYGLLGNVYFQVICGERFQRKDMAQLYE
(2) 47203
61403 TGRHAINFQQKGDDYGTILSYLP
WLKDYFPEATNYRILREVNNRLNDLIEAMVQKYLASYDENHMRCFLDRYIYEMKQSKPLEGDAFTFQ
(1) 61672
61872 YDQLVMILWDMLL
PTLSGSAIQLSMLLERLLLNPRVATKVQQELDGVVGHGRLPTLDDRVNLPYAEATLREALRIDTLVPSGISHVALEDTKL
CGYDIPKGCFVMLSLDVINNQREFWGDPENFRPERFLDESGKLSLKKDISVPFGGGKRLCVGETFSRNTLFLMFTALMQN
FNIKPRPGDPLPDLGQRITGVVTSMEPFWLRFEAR* 62501
>CYP304C1 1.1104_1 ae1
MVLISELIIAALLGLLIYRFYRYLFERPSENFPPGPPRL
PLLGGYPFMLALNYKHLHKAAARLSQLYKSKLIGLYLGPLPAVIVNDYDTVKEVLTRPEF
DGRPDLFMARLRDQHFQRR
(1)
GIFFTDSESWREQRRFFLRTLHHFGFGRRSPEAEADIQAGLEDVISLLRDGPKYEHEKAL
VDSAGFALCPTVFFAVFSNVLLRMIVGVRLAREDQAVMFE
VGKNAIAFHRNGDDYGMLLSYIPWIRHLFPKTTKYDLLRKVNQQANAVILSLAQKCES
SYDENDIRCLVDAYIQEMRATGSKGESTGKDEFGFQ
(1)
YDQLVIGAADFLVPPFSAIPAKICLILERLIQYPEVQTKMYRELNEVVGLNRLPTLDDRA
DLPYCDAVIREGLRIDALVPSGIPHMAVTDTQLNGYQIPKGTVIVNSLEFIHHQPEIFRD
PDSFMPERFLTPDGKLALDQDKTLPFGAGKRVCGGEQFARNALFLGVTSLVQNFTFQ
LPAGRACPDLDGRITGVIQTTPDFRLKFVSRR*
>CYP305A6 1.48_2 (305ae1)
1435 MITLVLSSVVIVSFIFWLWQDLQRPPNFPP (1) 1346
GPKWLPFFGNTLLIRNLARISGGQHLAFEALSKQYKSPVIGLKLGREHVVVALQ
YPAVHEALTKEAFDGRPDNFFIRLRTMGTR
(2?)
LGITFTDGPFWTEHNSFVVR
HLRQAGYGRQPMQLQIQNELNELIGIIRDLDSEPVWPGSILPTSVINVLWTFTTGSRIPR
DDQRLTRLLKLLQDRSKAFDMSGG
ILSQLPWLRHIAPEWTGYNLINRFNQEIHEFFKATIEKHHQDYTEEKCSDDLIYAFIK
EMKERKDDPCSTFTDVQLSMIILDIFIAGSQTTSTTIDIALMILAMNTEIQRKIYAEIDD
NFHPDEIPDQNCRTNLQYTEAFLLEVMRLYQIAPIGGPRRALSDCTLGGYRIPRNTTILM
GLHTVQMDPDHWGDPENFRPERFIGPDGKIINTERLIPFGLGRRRCLGDSLARSCMFTFL
VGILQKFSLRLPDSLEGPSLKLTPGITLSPKPYKVVFEPRLK*
>CYP305A5 1.48_1
AAGE01051792 70% to CYP305A2
MIVLVLTSVLIIAFSYWLLQELRRPPNYPPGPQWLPFIGNTPFVRKLARASGGQHLAFEALSKQYNSPVIGLKLGREYVV
VALQYPAVREVHSKEEFDGRPDNFFLRLRTMGTRLGVTCTDGPFWAEHRNFVVRHLRQAGYGRQPMQLQIQNELNELIGI
IRDMDGEPVWPGSILPTSVINVLWTFTTGSRIPRDDQRLARLLKLLQDRSKAFDMSGGVLSQLPWLRHIAPEWTGYNLLK
RFNQELHEFFMIIVERHHQEYHEEKCSDDLIYAFIKEMKDRKDDPSSTFTDLQLTMIILDIFIAGSQTTSITIDLAFMML
TMHTDIQKKIHAEIDENLHQDEMPQQNDRTSLPYTEAFLLEVQRFFHIVPVSGPRRALSDCTLGGYQIPKNTTILMGLRT
VHMDPEHWGDPECFRPERFLSPDGKIITTERLIPFGLGRRRCLGESLARACMFTFLVGILQKFSLRQPANCSEKPSPKLL
PGITLSPKPYKVIFEPR.
>CYP306A1 1.133_2
MYLILGIVLILTYVLWTLLDRRGKPPGPFGLPILGYLPFIDSIKPYETLTNLAKRYGPVYSLRMGQVDAVVLTAPDLIRD
TLKREETTGRAPLFITHGIMGGHGIICAEGNLWRDQRRLSTEWLRKMGMTKFGPTRATLEARILIGVNELLEDLRRESEK
VFAFDPAPLLHHILGNLMNDIVFGLQYERDDATWRYLQHLQEEGVKHIGVSMAVNFLPFLRHLPSSKRIIEFLLNGKAKT
HKIYDSIIEKQRSRMEGGGSEVSDPGRHDDCILSNFLQETRRRETGARPELAFCSDVQLRHLLADLFGAGVDTTFTTLRW
LILFLALNKDAQERLRQEMASQLRGEPCLNDVDSLPYLKACVAEAQRLRTVVPLGIPHGAVSEITIAGYKVSKNTMIIPL
LWSVHMDPSLWPNPDRFDPDRFLDESGQYSAPAHFMPFQTGKRMCLGDELARMILLLYTGRLFWHFELDVFNGEGLDLTG
VCGITLTPPPFEIIFKERV*
>CYP307A1 1.427_1
MAYTLILVALMSLLSVVCYLKVLYEWHRKVRVQTVKSSRYAKKLQKLEESQPQEVEEAPVEFPQAPGPYPWPVLGSAAII
GQYPAPFMGFSALAKKYGDVYSIRIGQGQCLVVSSLELIREVLNQNGRYFGGRPDFLRYHQLFGGDRNNSLALCDWSSLQ
QKRRNLARKHCSPSDASSYYQKMSDVGVAEMHYFMDQLTDVVTPGQDFKVKPLIMQACANMFSKYMCSVRFEYDDAGFQK
MVHSFDEIFYEINQGYAVDFMPWLAPFYFRHMSKLSSWSNYIRGFILERIVNEREQNLGEDEPERDFTDALLKSLREDPS
VSRDTIMYMLEDFIGGHSAIGNLVMLALGYVAKNPEIGARIQQEIDHVTDKGLRNVTLYDTESMPYTVATIFEVLRYSSS
PIVPHVATENTCIGGYGVQTGTVVFINNYDLNTSEKYWDHPERFDPSRSNESQKQILRVKKNIPHFLPFSIGKRTCIGQN
LVRGFSFIMLANILQKYDVHTNDPAQIKMKPACVAVPPDTYPLAFTQRSQ.
>CYP307B1 1.224_1
MEKFTIFLFSSNTIYLLVACFLVTLIMLLLEVRQKISVKSDLVKLVKSFLFGQWLSVFTQNNKNRNLNDTEVKVLRRAPG
PKSYPIIGNLKDLDGYEVPYQAFSVLAKKYGPVVNLKLGVVDAVVINGIEHIKEVLINKAQYFDSRPNFRRYQLLFSGNK
ENSLAFCDWSEVQKARRDMLVPHTFPRNFSGRFNELNGVINDEIRLVIGESNVNRVIEIKPIIMNICANVFSQYFASHRF
ELEDPKFQKLVKNFDQIFYEVNQGYAADFLPFLLPLHHRNLKRMDQLAEEIREIMLETIINDRYDNWVEGNTENDYVDSL
INHVKSKIGPDMEWETALFALEDIIGGHSAVANFLVKTFGYIIQHPEVQQNIQSEVDRVLETEGKHTVDLSDRNHMPYTE
AVIMEALRLIASPIVPHVANQDSQIGGYDVPKDTLIFLNNYDLSMSENLWENPNDFVPERFLQNGRLVKPDFFIPFGAGR
RSCMGYKMTQLISFSIIANLLRSYTITPLSGHSYFVPVGSLAMPEKSYEFQINLRH.
CYP3 CLAN (CYP6 [47 seqs] and CYP9 [36 seqs] and CYP329B1)
>CYP6F2 1.1219_1
CYP6AL2 AAGE01012031 CYP6AL2v1 6T1.2
MTLLSIGVALLCVAAFAFLNYVFGYWKRRGIRQLTPHFPFGNFTDLFFGKASFPKVCENLYERSKQWRLLGGY
VLLRPILLVNDPQLAKDIMVKDFQHFHDRGPHVDEENDPLSGHLFSLAGEKWKHLRAKLT
PTFTSGRLKGMFQTLVDTGEVLQEYIQKYAEGEDVVEIREILARYNTDNIASVAFGIKID
SINNPNEPFRHIGRKVFEPNFRNNMRGLITFMVPKLNKYLKIKSVDDDVEKFILKVVQETLEYREKNGIVRRDMM
QLLLQLRNTGTVSVDERWDVETSDKFKKLTLKEVAAQAHVFFLAGFETSSTTMSFCLYEL
AKHPEIQRRVQAEIDSVTALHDGKLTYDSINDMRYLECCIDETLRKYPPVPVLNRECTQD
YKVPGMDFTIEKGTAIVLQIAGMQHDPQYYPDPMQFKPERFQDPEVKSKPYAPFGDGPRV
CIGMRMGKIQTKVGLCLLLSKFDFELFGHDEPELVMDPNNFVLTPVDGINLKVSCRE*
>CYP6F3 1.1219_2
AAGE01073711
MTPLSIGVALLCVAAFAFLNYVFSYWNRRGVQQLTPYFPFGNFSDLFLGKASFPRVCETLYERTKKWRLLGVYILLRPVL
LVNDPQLAKDIMVKDFQHFHDRGTHVDEENDPLSGHLFSLAGEKWKHLRAKLTPTFTSGRLKGMFQTLVDTGEVLQDYIH
TCAKNEEVVEIREILARYNTDNIASVAFGIKIDSINNPNEPFRQIGRKFFESNFRNNMRLMITFMVPKLNKYFKIKSVDA
EVEQFILGMAKETLEYREKNGVVRKDMMQLLIQLRNTGTVSVDERWDVETSTNSKKLTIGEVAAQAHVFFLAGFETSSST
MSFCLYELAKNPEVQRKVQSEIDSVTALHDGKLTYDSINEMRYLECCIDETLRKYPPVPVLNRECTKDYKVPDSDITIEK
GTAVILQISAMHHDPQYYPDPLRFVPERFLDPDMKGKPYAPFGDGPRICIGLRMGKIQTKVGLCLLLSKFNFELYGHKES
ELVMSPNNFLNTPVNGINLKVSCRE.
>CYP6M5 1.371_12 CYP6M5
CYP6M5v2 6I1.1
MEVITITLLTILILLLIYVLHLLRRQIHFFKDRNVPYKPASFERLDKTIHPAMHFLRWYKQFKGQYPLSGVFMFIKPIVI
PLDLELIKRILVKDFQYFQNRGIYYNERDDPLSAHLFSLEGAKWRNLRAKISPTFTSGKMKMMYPTMVAAGKQFSEYLEE
KVGDGNELEMRDLLARFTTDMIGTCAFGIECNSMKEPNSKFREMGRKHFEAPRNVLKDAFKMTAPGLARFLRVTEILPDV
SEFFMDVVKSTVEYRMKNNVRRNDFMDLLIAMLDDKTEGSESLTISEIAAQAYVFFIAGFETSSTTMTWALHELSRNPDI
QEEGRKCVQEVLEKYNGVMSYEAIMEMTYIDQIINETLRLYPPVPMHFRVVSKDYHVPETDTILPAGTFTMIPVYAIHHD
EDIFPEPEKFDPTRFTPEEVNKRHAFAWTPFGEGPRVCIGLRFGMMQARIGLALMLKNLRFSPGPKTCTEMEFQPQNFIL
SPKEGLWLNVEKI*
>CYP6M6 1.371_11 CYP6M6
AAGE01004894 CYP6M6 6T1-1
MDVFLLIAAFVLLVAYGLHLLRKQVNFWADRNVPHNPVNFRQTVDQTVHMARRFQGYYHQFK
GQYPFAGMYLFTKPVALAIDLELLKCIFVKDFQYFHDRGTYYNEKDDPLSAHLFNLEGN
KWRNLRSKISPTFTSGKMKMMYPTMIAAGKQFSEYMDEKVGVEQELELKDLLARFTTDVI
GMCAFGIECNSMKDPNAEFREKGRMHFETPRNRKKDMMCSIAPKLARMMGLKQIIPDLSD
FFLGVVRETIDYRVKNGVRRNDFMDLLIGMLTGENVELGP
LTFNEVAAQAFVFFVAGFETSSTTMTWALYELSVNQDIQEKGRKCVRDVLEKYNGEL
SYETIMEMSYIDHILHETLRKYPPVPVHFRIVTKDYKVPNTETVLPAGTSVMIPVYAVHHDPEIFPDPK
RFDPDRFTTEEINKRHPYAWTPFGEGPRICIGMRFGMMQARIGLALLLNNFRFSSG
KKSTVPLDFTAKSFILSPDEGLWLKVEKL*
>CYP6M9 1.371_13
AAGE01032555 CYP6M5v2 6I1.1
MEVITITLLTILVLLIAYASHLLRRQIRFFKDRNVPHIPASFELLDKTIHPAKHFLRWYKQFKGQYPLTGVIMFIKPIAI
PLDLDLIKRILVKDFQYFQNRGIYYNERDDPLSAHLFSLEGAKWRSLRAKISPTFTSGKMKMMYPTMVAAGKQFSEYLEE
KVEDGNELEMRDLLARFTTDMIGTCAFGIECNSMKEPNSKFREMGRKHFEAPRNALKDAFKMTAPGLARFLRVTEILPDV
SEFFMDVVKSTVEYRMKNNVRRNDFMDLLIAMLDDKTEGSESLTINEIAAQAYVFFIAGFETSSTTMTWALHELSRNPDI
QEEGRKCVQEVLEKYNGVMSYEAIMEMTYIDQIINETLRLYPPVPMHFRVVSKDYHVPETDTILPAGTFTMIPVYAIHHD
EDIFPEPEKFDPTRFTPEEVNKRHAFAWTPFGEGPRVCIGLRFGMMQARIGLALMLKNLRFSPGPKTCTEMEFQPQNFIL
SPKEGLWLNVEKI.
>CYP6M10 1.371_14
AY433475 AAGE01031181
MEPITIILVTILVLLLTYGFHLIRRQLRFFKDHNVPHIAGNFVLIDKTQHPANHFLRWYKQSKGQYPLTGVFMFIKPIAI
PLDLELIKRILVKDFQYFQNRGMYYNERDDPLSAHLFSLEGAKWRSLRAKISPTFTSGKMKMMYPTMMAAGKQFSEHLEE
KMSEENELEMRDLLARFTTDMIGTCAFGIECNSMKEPNSKFREMGRKHFESPRSGLKDLLKITAPGLARFFGVTEILPDV
AEFFMDVVKSTVEYRMKNNVRRNDFMDLLIAMLDDETEGSESLTISEIAAQAYVFFIAGFETSSTTMTWALHELSRNPEI
QEEGRKCVQEVLEKYNGVMSYEAIMEMTYIDYIINETLRLYPPVPLHFRVVTKDYPVPGTDTVLPAGTFTMIPVYAIHHD
EDIFPEPEKFDPTRFTPEEVSKRHAYAWTPFGEGPRICIGLRFGMMQARIGLALLLNNLRFSPGPKSCTKMEFQPENLIL
TPKQGLWLKVEKV.
>CYP6M11 1.371_15
AAGE01105997
MEPLDVAITVVMVALAVYMYLDKKHSYWADRKVPFVKPKFFYGNAKEISQTMQVGQVFQQFYHELKGRSPFGGIYMFTAPVAVVTDLELLKCIFVKDFQYFHDRGTFYSEKGDPLSAHMFNLEGNKWKMLRNKLSPTFTSGKMKMMFPTIVAAGKQFHDFMDEKVKQESEFELKDLLARFTTDVIGMCAFGIECNSIKDPDAQFRVMGRKLFTTGRSKPKSFLMNTMPKVAKLLRLRIFPADVSDFFMKVVRETIDYRMANNVHRNDFMDLLIQMRNPDENKSSEGLLSFNEIAAQAFVFYLAGFETSSTLLTWTLYELAVNQDIQEKGRQHVKEVLKKHDGEMTYESITSMKYLDQILNEALRKYPPVPVHFRETSKDYTVPDSNIVIEGGTRLFVPVYAIHHDPEIFPNPEQFNPDRFTPEEEQKRHPYAWTPFGEGPRICIGLRFGMMQARIGLAYLLNSFKFSIGEKCKVPLEFDVKSFILAPKGGLWLKVEKI.
>CYP6N6 1.371_4
AAGE01504815 100% to CYP6Nae1 88% to CYP6N3v1 Aedes albopictus CYP6N6v1 6T1.4
MWIYLTVLALTLAVLWVRKRYAYWKERGIPYVEPSFPAGNIR
GMGRKEHFSTQMQRCYKELKGKGPVGGVFFFINPVPLALDLDFIKTVLVKDFQYFHDRSI
YYNEKDDPLSAHLVALEGAKWKNLRTKLTPTFTSGKMKTMFPTIIGVADEFQKMMKNEVV
GNTEIEMKDILARFTTDVIGTCAFGIECNSLQDPNAQ
FRRMGRKIFSVAKGRLLKLITAQQFRSLARMLGITLIDK
DVSDFFIGAVRDTIKYREENKIERNDFMSLLMKLKNDESSQDTNSGDVE
TLTVEQIAAQAFVFFLAGFETSSTAMSNSLYELAQNSDLQNKARKSVMDAIKKYGSLTYE
AMQDMQYIDQCINESLRKYPPASNLTRTVSTDYKLPDSNVVLQQGSTLIVPVYALHHDA
EYYPDPEKYDPDRFTPEEVAKRNPYCFLPFGEGPRNCIGMRFGMLQARVGLAYLLRDFSF
TLSNKTPVPLKISPHSPILTSEGGLWLNVRKL*
>CYP6N9 1.371_1
AAGE01173027
MIALLLIGAVTLVFLFVKQRFNYWKVRGVPYVRPTFPLGNLWGIGTKKHLSEGLEDLYVQLKGKAQLGGIYFFINPVVLVTDLDLIKTILIKDFNFFHDRSIYYNEKDDPLTAHLFTMEGIKWKNMRVKLTPTFTSGKMKLMFPIVRDCANELEKCISKEIVDGKEIEVKDILARYTTDVIGNCAFGLECNSLHNPNAEFREMGRKVFQLQGLGFLKLLLTQQFSTLSRALGATVLQPDVAKFFLKTVSDNVDYREKNKIERNDFIDLMIKLKNGQTLEHDKSDQRVEKLSIEQVAAQSFVFFFAGFETSSTLMSFCLYELAQNQDLQDKARKDILDTLNKHGSLSYEAVHEMKYLENCISETLRKHPPASNIFRTATQDYTVPGTSLTIEKGTSVMIPTLAIHRDPEYYPDPMKFDPDRFTADQVAARHPFAFLPFGEGPRVCIGMRFGLMQARVGLATLLKNFRFTVGERLETPAQLDPSSAILLIKGGLWLKVDKI.
>CYP6N10P 1.371_2p
AAGE01078584 pseudogene 100%
MLLYLLLTVVTLAYLWIGRRYSYWKQRSVPYVEPRFPFGNLQGLNKRHFGLLAQDVYSKL
KGSGSKFGGMFFFVNPVAVILDLDFAKDVFVKDFQYFHDRGVYSNEKVDPITSHLVAMEGIKWKNLRAKLTPTFTSGKMKMMFPTITAVADEFRKCMVNEVDKGGEIEMKEFLARFTT
DVIGSCAFGLECNSLADPEAEFRKMGKKALTMSPMGFLR
RILSVTFRDLAKFLGVRISDPDVATFFMNVVRSTIEYRERNKVQRNDFMDLLIKLKNVEPIDENTNQLGPLTFNEIVAQAFVFFLAGFETSSTTMCFCLYELAKNQELQDKARRNIDEVLAKYGTMTYEAVH
EMRYMENCINESLRKYPPLPNILRNVNKPY
>CYP6N11 1.371_3
AAGE01020246 Charle’s version 100%
MLLFLLLSVVTAAYLWVIWRYSYWKRRSVPYVEPSFPFGNLQGLNKRHFGLLTQDVYSKL
KGTGCKFGGMFFFVNPMVVILNLDFAKDVFVKDFQYFHDRGEYSNEKADPIMAHLVTMEG
TKWKNLRTKLTPVFTSGKMKMMFPIITAVAEEFRKCMAKEADKGEDIEMKELLARFTTDV
IGNCAFGLECNSLMDPEAEFRKMGRKAMAMSSADFLRRKLCNSFRGLAKLLGVRLSDPDV
SDFFMNAVRSTIEYRERNKVQRNDLMDLLIKLKNAELIDEKSDRLGPLTFNEIAAQAFVF
FLAGFESSSTAMSFCLYELAKNQELQDKARRNINEVLVKHGTLTYEALYEMTYIENCINE
SLRKYPPVTNIVRNVSKPYRVPGMNVTLEEDCRVLLPVYAIHHDPSLYPNPDQFDPERFN
PENSAARHPMAFVPFGEGPRICIGLRFGSMQARIGLTYLLKNFRFTLSEKMHDPLKMMSN
TIILASEGGLWMRIEKL.
>CYP6N12 1.371_5
AAGE01273771 100% to CYP6Nae2, 85%
to CYP6N3v1 Aedes albopictus
MLIYLTVLALTLAVLWIRKRYSYWMDRGILYVEPS
FPAGNLRGMGRKEHLSSQMQRCYKELKGKGPVGGMFFFINPVALAMDLDLIKSVLVKDFQ
YFHDRSVYYNEKDDPLSAHLFTMEGAKWKNLRAKLTPTFTSGKMKMMYPTIIGVADEFQK
LMKSEVSS
NAEIEMKEILARFTTDVIGTCAFGLECNSLHDPDAKFRAMGRKIFSFANGRF
LKAVIAQQFRSLARSLHIALVDKEVSDFFLGAVRDTIKYREENKIERNDFMSLLMKLKDD
GNTGNTETLTVEEIAAQAFVFFLAGFETSSTAMSYCLYELAQNSDLQNKARKSVMDSIKK
HGSLTYEAMQDMQYIDQCINESLRKYPPASTLTRSVSKDYKLPNSNVVLQQGSTLIVPVYA
LHHDAEYYPDPEKYNPDRFTPEEVAKRNPYCFLPFGEGPRICIGMRFGMMQARVGLAYLL
RDFSFTLSSKTPVPLKISPRSPVLTSEGGLWLKVQKL*
>CYP6N13 1.371_7 476419050 52% to CYP6N3, 63% to 6N2
102508
MWIFLLLSIAVLLILQVRRKYSYWKRHGVPFIQPRFPFGSITPVGDRVHSSQLMARFYNQ 102687
102688
LKGTYPFAGMYFFTNPVVLALDLDFIKNVLVRDFQYFHDRGLYHNEKDDPLTCHLFNIEG 102867
102868
TKWTNLRRKLLPTFSSGKMKMMCPTILAIADRFRTAIENSISDQNEIEMRDFLARFTTDV 103047
103048 IGTCAFGIDCNSLENPDAEFLKMGNKIFEVPTSRIIAYFFVSTFQELSKKLHIKAVPEDV 103227
103228
SRFFYKVVRETMAYRQSSGVQRNDFMNLLMQLKEKGELEGSDEKLGTLTLDEVVAQAYVF 103407
103408
FLGGYETSSTNMCFCLYELALNGEIQEKARECVQKAVAKHGGLNYEALMDMPYLEQCIY (1) 103584
EALRKYPPIANLFRSVTQDYNVPNSNVMLPKGMNVWIPIYAIH 103767
103768
HDPEFFPEPELFDPERFTQEECEKRKPFTYMPFGEGPRTCIATRFGMMETKTGLATLLMN 103947
103948
FKFTKSARLEVPPKFSTKHVMLTPVGGLWVKVEKIEQ* 104061
>CYP6N14 1.371_8 AAGE01021887
112574
MWLNLLVMVFALSVILVRRRYSYWKRIGVPFIQPRFPLGSIGSIGTRIHSSQLLAQFYQQ 112753
112754
LKGSHPFAGIFYFLQPVALALDLEFVKNVMVRDFQYFHDRGLYYNEKDDPLSSHLFNIEG 112933
112934
TKWTTLRRKLVPTFSSGKLKMMCPTVVSVADRFKMCIEKSIAKEEAIEMRELLARFTTDV 113113
113114
IGSCAFGIECNSLENPDDKFRKMGEKVFDVSPFAILAFFFLSTFKDLARKCRISITDSEV 113293
113294 AAFFSTIVQKTITYREKNNVQRNDFMNLLMQMMKKNKEDESEENSVTLTLDEVVAQSYVF 113473
113474
FLGGFETSRTTMSYCLYELSLNQEVQNRARKCIQSAVAKHDGLNYEALMDMPYLEQCIN (1) 113650
113709
ESLRKYPPISNALRSTTKDYAVPGTEVILKKGTDVIVPIYAIHHDPEYYPDPELFDPD 113882
113883 RFSADQCAKRKPFTFMPFGEGPRMCVASRFGMMETKIGLAAMLMSFRFSKCEKSIVPLKI 114062
114063
SPNHLMLTPAGGLWLKVEQLESDETEMGFSKLISDERVNRLGYSM*
>CYP6N15 1.371_9
AAGE01004071 100% to CYP6Nae4
MWNLSTSSNPHTIVPAHPKEILLLATSSVPFIPARFPVGSFDGVGVRNHPSQLLAKFYR
QMKGLHPFVGVYYFLQPVVVVLDLDFAKTILIRDFQYFHDRGLYYNEKDDPISGNLLHLE
GSRWTNQRKKLIPTFSSGKLRMMCPTILKVADNLKVSFERYVAERDEIEIKDILARFSTD
VIASCAFGLDCSSLLEADDEFRRMGTKVFDISGWKLLKLFFVFAFGNVARRCHMKLIDED
ISQFFFKVVRETIDFRKKNHVHRKDFLNLLIQLKDNG
ELEGSNEKLGTLTLNEVVAHSFVFFLGGFETASTTMSYCL
YELSLNEEVQERARQCVKAAIHKYGDLNYDDLLDMPYLEQCINETLRKYPPSTIYRIVTQ
NYHVPDSSIVFPKGMSVMIPVYAIHHDPEFWPSPELYDPDRFAPEECVSRNPLTFIPFGE
GPRMCVAARLGVLQTKIGLATLLMNFRFSRCKNSTEPLQYSPKHFILTPVGGLKMRVEKIQ*
>CYP6N16 1.457_3
AAGE01005098 100% to CYP6Nae3
MWIYLLIAAITLSVLLVRRKYSYWKRHGVPYIKPTFPFGNIRPAGNRVHSSQLMTRYYNELKGKHQFGGIFFFTNPVALA
LDLEFIKDVLVRDFQYFHDRGMYYNERDDPISGHLFNIEGTQWTNLRKKLLPTFSSGKLKMMSPTIISVAERFQECLEKC
ITVDTEIEMKDLLARFTTDVIGTCAFGIDCNSLNDPEVEFRKMGNKMFELPTGRILKFFFISTFKNLARKARLKSVPEDV
SEFFFRVVRETIDYREKSHIQRNDFMNLLMQLREKGALEGSDEKVGTLSMNEVVAQAFVFFLGGFETSSTTMSYCLYELS
LHEDIQERARECVQSAIAKHGGFNYDAVMDMNYLELCINESLRKYPPGANLVRCATKDYQVRNSSVVFKKGMSVMVPIYA
IHHDAEYYPDPERYDPERFGVEELAKRPPFTFMPFGEGPRICIAARFGMMESKIGLAALLMNFKFSKCSKSIVPLVISNK
HVVLTPAGGLWLKVEKLEQ.
>CYP6N17 1.457_2 AAGE02018066.1
60% to 6N2
319978 MWIYLLIGIITSLVLFVRRKYLFWERQGVPFIKPKFPFGNLLVNGKRVHTSQLTTYYYNA 319799
319798
LKGKKHPIGGVFFFTTPFAVVLDRELMRNVLIQDFQHFHDRGLYYNEKDDPISCHLFNIE 319619
319618
GSYWTNLRKKLSPIFSSGKLKLMCPMVITIAERFQKCLSKSITQNQQEAEMKEWLNRFTI 319439
319438
DVIGTCAFGIECNSLTNPEEKFRKMGVKMFHVANSRIIKFFFISLFKNLAKKVHIKSVPE 319259
319258
DVSEFFFKVIRKTIAFREMNHVLRNDFINLSMQLMADGKLEGSDEDVGKITLNEVVAQSF 319079
319078
VFFLAGYETSSTVMMFCLYELSLQEDIQRRARENVITAVSRHGGLNYDALMDMGYLDQCV 318899
318898 N (1)
ETMRKYPPAGNLGRCVTKDYNIPNTNITLRKGLNVVIPVH 318719
318718 GIHHDAEYYPDPERFDPERFSAEESTKRLPFTFMPFGEGPRNCIAARFGMLMAKVGVASM 318539
318538
LMRFQFSKCSKTAVPLVISPKHASMSPEGGMWLKVKEIK* 318419
>CYP6P12v1 1.702_1
AAGE02023125.1
48326
MLPLLLAVVTILLTAAALYIRSRHRFWSDRGIPCAPNPEFLFGHVRGQVTNKHAAYVNRE 48147
48146 LYQQFKARGEGFGGYSFFAVPAVIIVDPELVKTILVRDFAVFHDRGIYNNPKDDPLSGQL 47967
47966
FLLEGLQWKILRQMLTPTFTSGRMKAMFGTIMDVAEEFRQFLVDSRKRESVIEMKEILAS 47787
47786
FTTDVIGTCAFGIECNTLKNPDSDFLKYGKKVFEQRVSTLMKFIFASLFKDLARKLRIKI 47607
47606
TDAGVEKFFLGLVRETVEFREKNNVLRNDFMNLLLQLKNKGRLVDQLDEADEVAARGLTM 47427
47426
EELAAQCFVFFIAGYETSSTTMNFCLYELAKNPDIQEKLREDIEEAVASNSGRVTYDL (0) 47253
44758
GLRYLDNVVN (1) 44729
44670
ETLRKYPPIESLNRVPTSDYTVPGTKHVLPKQTMITIPIYALHHDPDFYLDPDNFD 44503
44502
PDRFLPEAAQARHPYAFIPFGEGPRNCIGMRFGLMHTKIGLITLLRNFRFSPSPKTPDKI 44323
44322
AFDVKSFVLSPDGGNYLRYDKI*
44254
>CYP6P12v2 AAGE02030882.1
96% to AAGE02023125 allele?
8678
MLPFLLAVVALLLTAAGLYIRSRHRFWSDRGIPCAPNPEFLFGHVRGQVTNKHAAYVNRE 8499
8498
LYQQFKARGEGFGGYSFFAVPAVIIVDPELVKTILVRDFAVFHDRGIYNNPKDDPLSGQL 8319
8318
FLLEGLQWKILRQMLTPTFTSGRMKAMFGTIMDVAEEFRQFLVDSRERESVIEMKEVLAS 8139
8138
FTTDVIGTCAFGIECNTLKNPDSDFLKYGKKVFEQRMSTLFKFIFASLFKDLARKLGVKI 7959
7958
TDAGVEKFFLGLVRETVEFREKNNVMRNDFMNLLLQLKNKGRLVDQLDEADEVAARGLTM 7779
7778 EELAAQCFVFFIAGYETSSTTMNFCLYELAKNPDIQEKLREDIEEAVASNGGRVTYDLVM 7599
7598
GLRYLDNVVN (1) 7593
7510
ETLRKYPPIESLNRVPTSDYTVPGTKHVLPKQTMITIPIYALHHDPDFYLDPDNFD 7343
7342
PDRFLPEAAQARHPYAFIPFGEGPRNCIGMRFGLMQTKIGLITLLRNFRFSPSAKTPDKI 7163
7162
AFDVKSFVLSPDGGNYLRYDKI*
7094
>CYP6S3 1.371_6 AAGE01028822
Nelson’s version 100% to CYP6Sae
MILILLLLAATALFFRWINAYRARYQFWKEHNVPHLEPRFPVGNAGDILKSTIHFAHIMDNLYRELKHFGDYAGIYFFRD
PVLVVLSPEFAKTVLVKDFNYFLDRGVYSNEKDDPLSANLFFMEGHRWRKLRAKLTPTFTTGKLKAMFHTILAVGEQFDR
YLQDYTKQKDEVEVKDLLARFTTDIIGSCAFGIDCNSLENPESKFRQMGKRMINFPKLKALKIFFAMMYRKQARWLRIRF
NDEDVSDFFFAVVRDTIRYREENNFERKDFMQLLIELKNKGYMEDDGEYVEELQGGRLEKLTFEEIAAQAFVFFFAGFET
SATTMTFALHLLASNQEVQDRGRKCVYEVLERHDGKLSYEALMEMTYIDCIIQETLRIYPPVATIHRITTKPYKLPNGSV
LPEGVGVVIPNLAFQRDPEFFPEPMQFRPERFFEDEKDKRHNFCHLPFGEGPRICIGMRFGLLQTRMGIAMLLKNYRFRL
CPKSVFPLKTDPINLIYGPAGDVWLGIEKIQ.
>CYP6Y3 1.371_10
AAGE01054542 76% to 6Y1
MWLVYLVWLVAAVLLAVYLWIKKRFNFWKDRGVEYIEPEFPFGNFKTLGKVEHIAPITQR
HYDYFKQKGVPYGGVFMLTSPLLYILDTKLIKTLLVKDFNHFPNRGVYFNEKDDPLSAHMFAI
EGNKWKTLRNKLSPTFTSGRIKMTFPLVVGVCQQFCDHLGEVVQQSNEVEMHDLLSRYTI
DVIGTCAFGIDCNSFREPDNEFRKYGKIAFDKLPHSPLVVYLMKAFRSYANAFGMKQLHE
DVSSFFSKVVKDTIEYRESNNVVRNDFMDLLLKLKNTGRLEESGEEIGKISFEEIAAQAF
IFFTAGYDTSSTAMTYTLYELALNQKAQEKARKCVLDIFAANNGTLTYESVGNMGYLDQC
INETLRKHPPVAILERNADRDYKLPDSDIVIKKGRKIMIPTFAMHHDAEHFPDPERYDPDR
FSPEQVACRDPYCYLPFGEGPRICIGMRFGTIQARVGLASLLKRFRFRVCDKTQIPVRYSK
TNFILGPANGVWLRVEKL*
>CYP6Z6 1.371_16
CYP6Zae2
MFIYTFALFWLALVLVLRYIYSYWDRNGLASIKPQIPYGNLKSVAQK
TQSFGVATCELYWKSQERLAGIYLFFRPAVLIRDAHLAQRIMTTDFSYFHDRGVYCNEEI
DPFSANLFAL
PGKRWRNLRHRFTPLFTSGQLRCMMPTILDVGHKLQKFLEPAAERQEVVDIREIVSRGVL
ELIASLFFGFEADCINDPDDAFSKTLREFQLGGFMNNFRTACTFVCPELLQVTRISSLSP
QMIKFATDVVTKQIEHREKNNVSRKDFIQLLIDLRREEANNNEVALSFEQCAANVFLFYV
AGSDTSTSAITFTLHELTQNPEVMDKLQSEIDEMLVQTNGELTYTAIKELPYLDLCVKET
LRKYPGLAILNRKCTKSYAVPESSVVIQEGTQIMIPLLAYGMDEKYFPEPERYYPERFNKQSKNYDEKAYYPFGEGPRNCI
AYRMGVMVSKIGLILLLSKFKFEATQGPKIVFSAATVPLVPKGGIPVKISNR*
>CYP6Z7 1.371_17
AAGE01005406
MLFVYTLTILSIAITLVLKFVYSYWDRYGVQNIKPHIPFGNLKTVVKKTESFGVAINQLY
WQTKGQLVGIYLFFRPAILIRDAHLAQQIMTTDFNHFHDRGVYCNEEGDPFSASLFSLPG
KRWRNLRNKLTPLFTGGQLRGMMPTILAVGDKLX
KHLEPVAENREPIEIRDIVSRFV
LEIIATVFFGFEANCIKDRNDAFCRVLREAQRESMYTNFRAAAVFVCPGLLKYTGISSLE
PEVKEFVSGIVTEQIEHREKNGATRKDFIQQLIELRREDSQNQNVRMSIEQCAANVFLFY